LOCUS       NC_011134            2024171 bp    DNA     circular BCT 30-SEP-2008
DEFINITION  Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome.
ACCESSION   NC_011134
VERSION     NC_011134.1  GI:195977156
PROJECT     GenomeProject:30781
KEYWORDS    .
SOURCE      Streptococcus equi subsp. zooepidemicus MGCS10565
  ORGANISM  Streptococcus equi subsp. zooepidemicus MGCS10565
            Bacteria; Firmicutes; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2024171)
  AUTHORS   Beres,S.B., Sesso,R., Pinto,S.W., Hoe,N.P., Porcella,S.F.,
            Deleo,F.R. and Musser,J.M.
  TITLE     Genome sequence of a lancefield group C Streptococcus zooepidemicus
            strain causing epidemic nephritis: new information about an old
            disease
  JOURNAL   PLoS ONE 3 (8), E3026 (2008)
   PUBMED   18716664
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2024171)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2008) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 2024171)
  AUTHORS   Beres,S.B., Sesso,R., Pinto,S.W.L., Hoe,N.P., Porcella,S.F.,
            DeLeo,F.R. and Musser,J.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2008) Center for Molecular and Translational
            Human Infectious Disease Research, The Methodist Hospital Research
            Institute, 6565 Fannin Street, Houston, TX 77030, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP001129.
            Source DNA and bacteria available from American Type Culture
            Collection (ATCC).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2024171
                     /organism="Streptococcus equi subsp. zooepidemicus
                     MGCS10565"
                     /mol_type="genomic DNA"
                     /strain="MGCS10565; ATCC BAA1716"
                     /sub_species="zooepidemicus"
                     /culture_collection="ATCC:BAA-1716"
                     /db_xref="taxon:552526"
     gene            233..1585
                     /gene="dnaA"
                     /locus_tag="Sez_0001"
                     /db_xref="GeneID:6760380"
     CDS             233..1585
                     /gene="dnaA"
                     /locus_tag="Sez_0001"
                     /note="similar to ref|YP_601495.1| chromosomal replication
                     initiation protein [Streptococcus pyogenes MGAS10750];
                     Plays an important role in the initiation and regulation
                     of chromosomal replication. Binds to the origin of
                     replication; it binds specifically double-stranded DNA at
                     a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA
                     binds to ATP and to acidic phospholipids."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="YP_002122401.1"
                     /db_xref="GI:195977157"
                     /db_xref="GeneID:6760380"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEEDLIIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK"
     gene            1742..2878
                     /gene="dnaN"
                     /locus_tag="Sez_0002"
                     /db_xref="GeneID:6760876"
     CDS             1742..2878
                     /gene="dnaN"
                     /locus_tag="Sez_0002"
                     /note="similar to ref|YP_601496.1| DNA polymerase III
                     subunit beta [Streptococcus pyogenes MGAS10750]; DNA
                     polymerase III is a complex, multichain enzyme responsible
                     for most of the replicative synthesis in bacteria. This
                     DNA polymerase also exhibits 3' to 5' exonuclease
                     activity. The beta chain is required for initiation of
                     replication once it is clamped onto DNA, It slides freely
                     (bidirectional and ATP- independent) along duplex DNA."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III beta subunit"
                     /protein_id="YP_002122402.1"
                     /db_xref="GI:195977158"
                     /db_xref="GeneID:6760876"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKDFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            2956..3153
                     /locus_tag="Sez_0003"
                     /db_xref="GeneID:6760878"
     CDS             2956..3153
                     /locus_tag="Sez_0003"
                     /note="similar to ref|ZP_00784446.1| conserved
                     hypothetical protein [Streptococcus agalactiae COH1]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122403.1"
                     /db_xref="GI:195977159"
                     /db_xref="GeneID:6760878"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKRVLQP"
     gene            3274..3639
                     /locus_tag="Sez_0004"
                     /db_xref="GeneID:6760883"
     CDS             3274..3639
                     /locus_tag="Sez_0004"
                     /note="similar to ref|YP_001199566.1| Predicted
                     transcriptional regulator [Streptococcus suis 98HAH33];
                     Unknown, COG1396 Predicted transcriptional regulators."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122404.1"
                     /db_xref="GI:195977160"
                     /db_xref="GeneID:6760883"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATL
                     DLENLVTLAAVLEVTLDELVTGKESAIKVTKKTEKPMNVWEFLTEESKRPISKGDLLM
                     LLLVPIVLLGVYLIVIYFS"
     gene            3723..4838
                     /locus_tag="Sez_0005"
                     /db_xref="GeneID:6761764"
     CDS             3723..4838
                     /locus_tag="Sez_0005"
                     /note="similar to ref|YP_279474.1| translation-associated
                     GTPase [Streptococcus pyogenes MGAS6180]; GTP-dependent
                     nucleic acid-binding protein which may act as a
                     translation factor."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-dependent nucleic acid-binding protein EngD"
                     /protein_id="YP_002122405.1"
                     /db_xref="GI:195977161"
                     /db_xref="GeneID:6761764"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     ATPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKLEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            4995..5564
                     /gene="pth"
                     /locus_tag="Sez_0006"
                     /db_xref="GeneID:6761698"
     CDS             4995..5564
                     /gene="pth"
                     /locus_tag="Sez_0006"
                     /note="similar to ref|NP_687043.1| peptidyl-tRNA hydrolase
                     [Streptococcus agalactiae 2603V/R]; The natural substrate
                     for this enzyme may be peptidyl- tRNAs which drop off the
                     ribosome during protein synthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase Pth"
                     /protein_id="YP_002122406.1"
                     /db_xref="GI:195977162"
                     /db_xref="GeneID:6761698"
                     /translation="MVKMIVGLGNPGSKYQQTKHNVGFMAVDRLVKDLDISFTEDKAF
                     KALVGSAFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            5567..9061
                     /locus_tag="Sez_0007"
                     /db_xref="GeneID:6761703"
     CDS             5567..9061
                     /locus_tag="Sez_0007"
                     /note="similar to ref|NP_801268.1| putative
                     transcription-repair coupling factor [Streptococcus
                     pyogenes SSI-1]; Necessary for strand-specific repair. A
                     lesion in the template strand blocks the RNA polymerase
                     complex (RNAP). The RNAP-DNA-RNA complex is specifically
                     recognized by TRCF which releases RNAP and the truncated
                     transcript; the TCRF may replace RNAP at the lesion site
                     and then recruit the uvrA/B/C repair system."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="YP_002122407.1"
                     /db_xref="GI:195977163"
                     /db_xref="GeneID:6761703"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSTLLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDKIVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNATFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVHSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLETYQCQLPLVSAEAIVLRQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGIHRDYVTIQYQQSDRISLPVEQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQKAFEEDFAFVETDDQLRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIDVLSRFRSKKEQAESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTIDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            9030..10541
                     /locus_tag="Sez_0008"
                     /db_xref="GeneID:6760885"
     CDS             9030..10541
                     /locus_tag="Sez_0008"
                     /note="similar to ref|NP_814052.1| polysaccharide
                     biosynthesis family protein [Enterococcus faecalis V583];
                     Unknown, COG2244 Membrane protein involved in the export
                     of O-antigen and teichoic acid."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis family protein"
                     /protein_id="YP_002122408.1"
                     /db_xref="GI:195977164"
                     /db_xref="GeneID:6760885"
                     /translation="MRLNLEKLPHKTKQSSLLIVISSFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCCTSFLLSGILV
                     LSHKALASWMGAQQLAPSIIITAMVLLTIPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIAAALCYSVFGWTVYVTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGEVI
                     AIKDLTSLGLPTLVFLLFSVYLLVFQLVDSLLVKNILVNSGLSELTAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTALFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            10572..10844
                     /locus_tag="Sez_0009"
                     /db_xref="GeneID:6760884"
     CDS             10572..10844
                     /locus_tag="Sez_0009"
                     /note="similar to ref|ZP_00780251.1| S4 RNA-binding domain
                     protein [Streptococcus agalactiae 18RS21]; Unknown,
                     COG1188 Ribosome-associated heat shock protein implicated
                     in the recycling of the 50S subunit (S4 paralog)."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein 15"
                     /protein_id="YP_002122409.1"
                     /db_xref="GI:195977165"
                     /db_xref="GeneID:6760884"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRIKSDEEA"
     gene            10855..11202
                     /locus_tag="Sez_0010"
                     /db_xref="GeneID:6761743"
     CDS             10855..11202
                     /locus_tag="Sez_0010"
                     /note="similar to ref|YP_599604.1| Cell division protein
                     DIVIC [Streptococcus pyogenes MGAS2096]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIC"
                     /protein_id="YP_002122410.1"
                     /db_xref="GI:195977166"
                     /db_xref="GeneID:6761743"
                     /translation="MNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMFLFILPTYN
                     LVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYARAKYYLSRE
                     GEVIYPTPGLLPK"
     gene            11344..12630
                     /locus_tag="Sez_0011"
                     /db_xref="GeneID:6761733"
     CDS             11344..12630
                     /locus_tag="Sez_0011"
                     /note="similar to ref|ZP_00366568.1| COG2367:
                     Beta-lactamase class A [Streptococcus pyogenes M49 591]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase"
                     /protein_id="YP_002122411.1"
                     /db_xref="GI:195977167"
                     /db_xref="GeneID:6761733"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            12627..13910
                     /locus_tag="Sez_0012"
                     /db_xref="GeneID:6760881"
     CDS             12627..13910
                     /locus_tag="Sez_0012"
                     /note="similar to ref|YP_059329.1| tRNA(Ile)-lysidine
                     synthetase [Streptococcus pyogenes MGAS10394]; Ligates
                     lysine onto the cytidine present at position 34 of the AUA
                     codon-specific tRNA(Ile) that contains the anticodon CAU,
                     in an ATP-dependent manner. Cytidine is converted to
                     lysidine, thus changing the amino acid specificity of the
                     tRNA from methionine to isoleucine."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Ile)-lysidine synthase"
                     /protein_id="YP_002122412.1"
                     /db_xref="GI:195977168"
                     /db_xref="GeneID:6760881"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     ELQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHFRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFATGQLIRPFL
                     TVSKEELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIALSAESRLLL
                     QAFDDLTKGLAFHRLDCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFVIKKIIPKTDLNRESKMVSYGDPLDYGGYRFAFSGDLTD
                     KGHDIVIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTNEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            13915..14457
                     /gene="hpt"
                     /locus_tag="Sez_0013"
                     /db_xref="GeneID:6761742"
     CDS             13915..14457
                     /gene="hpt"
                     /locus_tag="Sez_0013"
                     /note="similar to ref|NP_606347.1| hypoxanthine-guanine
                     phosphoribosyltransferase [Streptococcus pyogenes
                     MGAS8232]; This Enzyme Acts Exclusively On Hypoxanthine;
                     It Does Not Act On Guanine (By Similarity)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine-guanine phosphoribosyltransferase
                     protein Hpt"
                     /protein_id="YP_002122413.1"
                     /db_xref="GI:195977169"
                     /db_xref="GeneID:6761742"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            14533..16452
                     /gene="ftsH"
                     /locus_tag="Sez_0014"
                     /db_xref="GeneID:6761729"
     CDS             14533..16452
                     /gene="ftsH"
                     /locus_tag="Sez_0014"
                     /note="similar to ref|YP_279483.1| cell division protein
                     [Streptococcus pyogenes MGAS6180]; Seems to act as an
                     ATP-dependent zinc metallopeptidase."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsH-like"
                     /protein_id="YP_002122414.1"
                     /db_xref="GI:195977170"
                     /db_xref="GeneID:6761729"
                     /translation="MIVIVVAGFQYYLRGTSTQSQQISYSKLIKHLKAGDIKSLSYQP
                     SGSIVEVKGKYEEPQKVSIDTGLSFLGNSAATEVTEFTALILPSDSVLKEMTSVADKN
                     GTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGGGGARGAMSFGKNKARSQA
                     KGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARIPAGVLLEGPPGTGKTLL
                     AKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRR
                     RGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRSDVLDPALLRPGRFDRKV
                     LVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVGADLENVLNEAALVAARR
                     NKAKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEAGHTIVGLVLSNARVVHK
                     VTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRVAEEIIFNAQTTGASNDF
                     EQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKSYSAQTAQMIDDEVRELL
                     NEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYETGKMPHDPENDEAEVHA
                     LSYDEIKDKMTEANE"
     gene            16542..18005
                     /locus_tag="Sez_0015"
                     /db_xref="GeneID:6760882"
     CDS             16542..18005
                     /locus_tag="Sez_0015"
                     /note="similar to ref|YP_059333.1| Amino acid permease
                     [Streptococcus pyogenes MGAS10394]; Involved in the
                     transport of the cationic amino acids (arginine, lysine
                     and ornithine)."
                     /codon_start=1
                     /transl_table=11
                     /product="cationic amino acid transporter - APC
                     superfamily"
                     /protein_id="YP_002122415.1"
                     /db_xref="GI:195977171"
                     /db_xref="GeneID:6760882"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGTANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPT
                     ALNGTFDPQKGTYIDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFIIVG
                     LFFIDTANWSPFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLHWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPKNATLVVGVLSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTVLGILVYTCYGYTHSQERGK"
     gene            18340..19674
                     /locus_tag="Sez_1962"
                     /note="16S RNA1"
                     /db_xref="GeneID:6761506"
     rRNA            18340..19674
                     /locus_tag="Sez_1962"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:6761506"
     gene            19868..19945
                     /locus_tag="Sez_1963"
                     /note="tRNA_01"
                     /db_xref="GeneID:6761132"
     tRNA            19868..19945
                     /locus_tag="Sez_1963"
                     /product="tRNA-Ala"
                     /note="anticodon TGC"
                     /db_xref="GeneID:6761132"
     gene            20203..23100
                     /locus_tag="Sez_1964"
                     /note="23S RNA1"
                     /db_xref="GeneID:6761154"
     rRNA            20203..23100
                     /locus_tag="Sez_1964"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:6761154"
     gene            23187..23302
                     /locus_tag="Sez_1965"
                     /note="5S RNA1"
                     /db_xref="GeneID:6761167"
     rRNA            23187..23302
                     /locus_tag="Sez_1965"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:6761167"
     gene            23348..23423
                     /locus_tag="Sez_1966"
                     /note="tRNA_02"
                     /db_xref="GeneID:6761114"
     tRNA            23348..23423
                     /locus_tag="Sez_1966"
                     /product="tRNA-Val"
                     /note="anticodon TAC"
                     /db_xref="GeneID:6761114"
     gene            23434..23509
                     /locus_tag="Sez_1967"
                     /note="tRNA_03"
                     /db_xref="GeneID:6761038"
     tRNA            23434..23509
                     /locus_tag="Sez_1967"
                     /product="tRNA-Asp"
                     /note="anticodon GTC"
                     /db_xref="GeneID:6761038"
     gene            23510..23585
                     /locus_tag="Sez_1968"
                     /note="tRNA_04"
                     /db_xref="GeneID:6761082"
     tRNA            23510..23585
                     /locus_tag="Sez_1968"
                     /product="tRNA-Lys"
                     /note="anticodon TTT"
                     /db_xref="GeneID:6761082"
     gene            23588..23672
                     /locus_tag="Sez_1969"
                     /note="tRNA_05"
                     /db_xref="GeneID:6761080"
     tRNA            23588..23672
                     /locus_tag="Sez_1969"
                     /product="tRNA-Leu"
                     /note="anticodon TAG"
                     /db_xref="GeneID:6761080"
     gene            23678..23753
                     /locus_tag="Sez_1970"
                     /note="tRNA_06"
                     /db_xref="GeneID:6761079"
     tRNA            23678..23753
                     /locus_tag="Sez_1970"
                     /product="tRNA-Thr"
                     /note="anticodon TGT"
                     /db_xref="GeneID:6761079"
     gene            23762..23836
                     /locus_tag="Sez_1971"
                     /note="tRNA_07"
                     /db_xref="GeneID:6761075"
     tRNA            23762..23836
                     /locus_tag="Sez_1971"
                     /product="tRNA-Gly"
                     /note="anticodon GCC"
                     /db_xref="GeneID:6761075"
     gene            23842..23929
                     /locus_tag="Sez_1972"
                     /note="tRNA_08"
                     /db_xref="GeneID:6761090"
     tRNA            23842..23929
                     /locus_tag="Sez_1972"
                     /product="tRNA-Leu"
                     /note="anticodon TAA"
                     /db_xref="GeneID:6761090"
     gene            23941..24017
                     /locus_tag="Sez_1973"
                     /note="tRNA_09"
                     /db_xref="GeneID:6761091"
     tRNA            23941..24017
                     /locus_tag="Sez_1973"
                     /product="tRNA-Arg"
                     /note="anticodon ACG"
                     /db_xref="GeneID:6761091"
     gene            24021..24097
                     /locus_tag="Sez_1974"
                     /note="tRNA_10"
                     /db_xref="GeneID:6761072"
     tRNA            24021..24097
                     /locus_tag="Sez_1974"
                     /product="tRNA-Pro"
                     /note="anticodon TGG"
                     /db_xref="GeneID:6761072"
     gene            24104..24182
                     /locus_tag="Sez_1975"
                     /note="tRNA_11"
                     /db_xref="GeneID:6761085"
     tRNA            24104..24182
                     /locus_tag="Sez_1975"
                     /product="tRNA-Met"
                     /note="anticodon CAT"
                     /db_xref="GeneID:6761085"
     gene            24198..24276
                     /locus_tag="Sez_1976"
                     /note="tRNA_12"
                     /db_xref="GeneID:6761089"
     tRNA            24198..24276
                     /locus_tag="Sez_1976"
                     /product="tRNA-Met"
                     /note="anticodon CAT"
                     /db_xref="GeneID:6761089"
     gene            24280..24372
                     /locus_tag="Sez_1977"
                     /note="tRNA_13"
                     /db_xref="GeneID:6761060"
     tRNA            24280..24372
                     /locus_tag="Sez_1977"
                     /product="tRNA-Ser"
                     /note="anticodon TGA"
                     /db_xref="GeneID:6761060"
     gene            24380..24458
                     /locus_tag="Sez_1978"
                     /note="tRNA_14"
                     /db_xref="GeneID:6761073"
     tRNA            24380..24458
                     /locus_tag="Sez_1978"
                     /product="tRNA-Met"
                     /note="anticodon CAT"
                     /db_xref="GeneID:6761073"
     gene            24478..24555
                     /locus_tag="Sez_1979"
                     /note="tRNA_15"
                     /db_xref="GeneID:6761070"
     tRNA            24478..24555
                     /locus_tag="Sez_1979"
                     /product="tRNA-Phe"
                     /note="anticodon GAA"
                     /db_xref="GeneID:6761070"
     gene            24556..24631
                     /locus_tag="Sez_1980"
                     /note="tRNA_16"
                     /db_xref="GeneID:6761069"
     tRNA            24556..24631
                     /locus_tag="Sez_1980"
                     /product="tRNA-Gly"
                     /note="anticodon TCC"
                     /db_xref="GeneID:6761069"
     gene            24656..24734
                     /locus_tag="Sez_1981"
                     /note="tRNA_17"
                     /db_xref="GeneID:6761065"
     tRNA            24656..24734
                     /locus_tag="Sez_1981"
                     /product="tRNA-Ile"
                     /note="anticodon GAT"
                     /db_xref="GeneID:6761065"
     gene            24739..24831
                     /locus_tag="Sez_1982"
                     /note="tRNA_18"
                     /db_xref="GeneID:6761045"
     tRNA            24739..24831
                     /locus_tag="Sez_1982"
                     /product="tRNA-Ser"
                     /note="anticodon GCT"
                     /db_xref="GeneID:6761045"
     gene            24838..25701
                     /gene="mreC"
                     /locus_tag="Sez_0016"
                     /db_xref="GeneID:6761046"
     CDS             24838..25701
                     /gene="mreC"
                     /locus_tag="Sez_0016"
                     /note="similar to ref|NP_346626.1| rod shape-determining
                     protein MreC [Streptococcus pneumoniae TIGR4]; Involved In
                     Formation Of The Rod Shape Of The Cell. May Also
                     Contribute To Regulation Of Formation Of
                     Penicillin-Binding Proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="YP_002122416.1"
                     /db_xref="GI:195977172"
                     /db_xref="GeneID:6761046"
                     /translation="MIIILIIVFLFSEVILLKKLNLSRLFFWLTSLALLVLTLVLLFR
                     VAVSPYLSMIIRNPVTKMDVIMSKPFAVIKEGAKELDGLMSAFSENKHLKKELRSYKL
                     EQLQVDKLKSENRELKELLGLNYGTDNQFAVKIISRNPYSWNKSLVIDSGKREIKEKS
                     LVISELGLIGRVTTASQSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTM
                     VASEFNSNDSISLDAKVYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTD
                     NLDYVLVVGKE"
     gene            25704..26207
                     /gene="mreD"
                     /locus_tag="Sez_0017"
                     /db_xref="GeneID:6761786"
     CDS             25704..26207
                     /gene="mreD"
                     /locus_tag="Sez_0017"
                     /note="similar to ref|NP_720504.1| putative cell
                     shape-determining protein MreD [Streptococcus mutans
                     UA159]; MreD (murein formation D) protein is involved in
                     the rod shape determination in Escherichia coli, and more
                     generally in cell shape determination of bacteria whether
                     or not they are rod-shaped."
                     /codon_start=1
                     /transl_table=11
                     /product="cell shape-determining protein MreD"
                     /protein_id="YP_002122417.1"
                     /db_xref="GI:195977173"
                     /db_xref="GeneID:6761786"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            26303..27481
                     /locus_tag="Sez_0018"
                     /db_xref="GeneID:6761695"
     CDS             26303..27481
                     /locus_tag="Sez_0018"
                     /note="similar to ref|YP_597626.1| Secreted protein
                     [Streptococcus pyogenes MGAS10270]; pfam05257, CHAP
                     domain. This domain corresponds to an amidase function.
                     Many of these proteins are involved in cell wall
                     metabolism of bacteria. This domain is found at the
                     N-terminus of the bifunctional Escherichia coli GSP
                     synthetase/GSP amidase, where is functions as a
                     glutathionylspermidine amidase."
                     /codon_start=1
                     /transl_table=11
                     /product="secreted antigen GbpB/SagA/PcsB, putative
                     peptidoglycan hydrolase"
                     /protein_id="YP_002122418.1"
                     /db_xref="GI:195977174"
                     /db_xref="GeneID:6761695"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLSTKIAEKESLISTLTKE
                     QQAAKKQVVALQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQYIGNYRGWFSPGAVSYIYPN"
     gene            27574..28548
                     /gene="prs"
                     /locus_tag="Sez_0019"
                     /db_xref="GeneID:6760874"
     CDS             27574..28548
                     /gene="prs"
                     /locus_tag="Sez_0019"
                     /note="similar to ref|YP_059336.1| ribose-phosphate
                     pyrophosphokinase [Streptococcus pyogenes MGAS10394];
                     Utilized by both the de novo and the salvage pathways by
                     which endogenously formed or exogenously added pyrimidine,
                     purine, or pyridine bases are converted to the
                     corresponding ribonucleoside monophosphates."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase protein Prs"
                     /protein_id="YP_002122419.1"
                     /db_xref="GI:195977175"
                     /db_xref="GeneID:6760874"
                     /translation="MEEKMSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDG
                     EIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYAR
                     QDRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADY
                     FDRHGLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGS
                     VEGKKCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEK
                     LIVLDTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            28908..29678
                     /gene="recO"
                     /locus_tag="Sez_0020"
                     /db_xref="GeneID:6760858"
     CDS             28908..29678
                     /gene="recO"
                     /locus_tag="Sez_0020"
                     /note="similar to ref|NP_268438.1| DNA repair protein RecO
                     [Streptococcus pyogenes M1 GAS]; Involved in DNA repair
                     and recF pathway recombination."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination and repair protein RecO"
                     /protein_id="YP_002122420.1"
                     /db_xref="GI:195977176"
                     /db_xref="GeneID:6760858"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLIEEGLDYDILTNIFEIQILDRFGVRMNFHDCVFCHSTNL
                     PFDFSHKYSGVLCPQHYHEDEGRYGLDPNVIYLINRFQTINIDELKTISVNADMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            29794..30801
                     /gene="plsX"
                     /locus_tag="Sez_0021"
                     /db_xref="GeneID:6760686"
     CDS             29794..30801
                     /gene="plsX"
                     /locus_tag="Sez_0021"
                     /note="similar to ref|YP_595752.1| fatty acid/phospholipid
                     synthesis protein [Streptococcus pyogenes MGAS9429];
                     Involved in fatty acid/phospholipid synthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid/phospholipid synthesis protein PlsX"
                     /protein_id="YP_002122421.1"
                     /db_xref="GI:195977177"
                     /db_xref="GeneID:6760686"
                     /translation="MKKIAIDAMGGDHAPKAIVEGVNQAIEAFSDIEVQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            30794..31042
                     /gene="acpP"
                     /locus_tag="Sez_0022"
                     /db_xref="GeneID:6760785"
     CDS             30794..31042
                     /gene="acpP"
                     /locus_tag="Sez_0022"
                     /note="similar to ref|NP_663822.1| acyl carrier protein
                     [Streptococcus pyogenes MGAS315]; Carrier Of The Growing
                     Fatty Acid Chain In Fatty Acid Biosynthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein AcpP"
                     /protein_id="YP_002122422.1"
                     /db_xref="GI:195977178"
                     /db_xref="GeneID:6760785"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            31193..31903
                     /gene="purC"
                     /locus_tag="Sez_0023"
                     /db_xref="GeneID:6760696"
     CDS             31193..31903
                     /gene="purC"
                     /locus_tag="Sez_0023"
                     /note="similar to ref|YP_138575.1|
                     phosphoribosylaminoimidazole-succinocarboxamide synthase
                     [Streptococcus thermophilus LMG 18311]; De novo purine
                     biosynthesis; seventh step."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole-succinocarboxamide
                     synthase PurC"
                     /protein_id="YP_002122423.1"
                     /db_xref="GI:195977179"
                     /db_xref="GeneID:6760696"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            32082..35822
                     /gene="purL"
                     /locus_tag="Sez_0024"
                     /db_xref="GeneID:6760680"
     CDS             32082..35822
                     /gene="purL"
                     /locus_tag="Sez_0024"
                     /note="similar to ref|YP_819618.1|
                     Phosphoribosylformylglycinamidine (FGAM) synthase
                     [Streptococcus thermophilus LMD-9]; Unknown, proposed to
                     phosphorylate an amide oxygen of the purine nucleotide
                     using ATP, activating the carbon of the resulting
                     iminophosphate for nucleophilic attack."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     protein PurL"
                     /protein_id="YP_002122424.1"
                     /db_xref="GI:195977180"
                     /db_xref="GeneID:6760680"
                     /translation="MNKRIFVEKKADFQIKAQILLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYTFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRRAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRAGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGEYIYYIPGQAISEVIDFEMIKSNFRSFAAIQARHKIS
                     SASAVKYGGIIETLALAAFGNQLGACVTLAELDRSLTAQLGGFVFTSKEEIAGAIRLG
                     QTTSDFTLIVNDVKLSGDRLLKAFEGSLEQVYPTVFQQAGDLQPVPVVTTALATQFKE
                     KIVQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVNTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRAAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVKVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGKPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVDID"
     gene            35941..37398
                     /gene="purF"
                     /locus_tag="Sez_0025"
                     /db_xref="GeneID:6760614"
     CDS             35941..37398
                     /gene="purF"
                     /locus_tag="Sez_0025"
                     /note="similar to ref|YP_279493.1|
                     amidophosphoribosyltransferase [Streptococcus pyogenes
                     MGAS6180]; De novo purine biosynthesis; first step."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase precursor protein
                     PurF"
                     /protein_id="YP_002122425.1"
                     /db_xref="GI:195977181"
                     /db_xref="GeneID:6760614"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLVTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEICDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            37455..38477
                     /gene="purM"
                     /locus_tag="Sez_0026"
                     /db_xref="GeneID:6760583"
     CDS             37455..38477
                     /gene="purM"
                     /locus_tag="Sez_0026"
                     /note="similar to ref|YP_138578.1|
                     phosphoribosylaminoimidazole synthetase [Streptococcus
                     thermophilus LMG 18311]; De novo purine biosynthesis;
                     fifth step."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase
                     protein PurM"
                     /protein_id="YP_002122426.1"
                     /db_xref="GI:195977182"
                     /db_xref="GeneID:6760583"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHSERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            38474..39031
                     /gene="purN"
                     /locus_tag="Sez_0027"
                     /db_xref="GeneID:6761655"
     CDS             38474..39031
                     /gene="purN"
                     /locus_tag="Sez_0027"
                     /note="similar to ref|YP_001449360.1|
                     phosphoribosylglycinamide formyltransferase [Streptococcus
                     gordonii str. Challis substr. CH1]; De novo purine
                     biosynthesis; third step."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase
                     protein PurN"
                     /protein_id="YP_002122427.1"
                     /db_xref="GI:195977183"
                     /db_xref="GeneID:6761655"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYGGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            39223..40725
                     /gene="purH"
                     /locus_tag="Sez_0028"
                     /db_xref="GeneID:6761679"
     CDS             39223..40725
                     /gene="purH"
                     /locus_tag="Sez_0028"
                     /note="similar to ref|NP_606360.1| bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase [Streptococcus
                     pyogenes MGAS8232]; De novo purine biosynthesis; ninth
                     step. De novo purine biosynthesis; tenth step."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional purine biosynthesis protein PurH"
                     /protein_id="YP_002122428.1"
                     /db_xref="GI:195977184"
                     /db_xref="GeneID:6761679"
                     /translation="MDLARELKHLGWDIISTGGTRLALEEAGVVTVAIDDVTGFPEMM
                     DGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNLYPFKETICRPDVTYD
                     VAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELASTGSTSYQTRQSLAAKA
                     FRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENPQQAADFYQRALPTTY
                     SIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHMNPCGIGQADDIETAW
                     DFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGYSKEALAVLTHKKKHL
                     RILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIVVTKRQPNEQEMAALA
                     FAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASVRIAIAQATGQLEGAVLASDAFF
                     PFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFTGVRHFRH"
     gene            complement(41103..42257)
                     /locus_tag="Sez_0029"
                     /db_xref="GeneID:6761613"
     CDS             complement(41103..42257)
                     /locus_tag="Sez_0029"
                     /note="similar to ref|YP_281392.1| autolysin
                     [Streptococcus pyogenes MGAS5005]; Unknown, surface
                     antigen; autolysin; putative choline binding protein."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="YP_002122429.1"
                     /db_xref="GI:195977185"
                     /db_xref="GeneID:6761613"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNAESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNRRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDPAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            42571..43875
                     /gene="purD"
                     /locus_tag="Sez_0030"
                     /db_xref="GeneID:6760875"
     CDS             42571..43875
                     /gene="purD"
                     /locus_tag="Sez_0030"
                     /note="similar to ref|YP_001034054.1|
                     phosphoribosylamine--glycine ligase [Streptococcus
                     sanguinis SK36]; De novo purine biosynthesis; second
                     step."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase protein
                     PurD"
                     /protein_id="YP_002122430.1"
                     /db_xref="GI:195977186"
                     /db_xref="GeneID:6760875"
                     /translation="MLKYVYKIRVMRCVMKLLVIGSGGREHAIAKKLLESKGVDQVFV
                     APGNDGMTLDGIERVDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQAGL
                     KAFGPSRLAAELEWSKDFAKQIMVKYGIPTAAYDTFSDFAKAKAYIEEKGVPIVVKAD
                     GLALGKGVVVAETVEQAVEAARDMLLDNKFGDSGARVVIEEFLTGEEFSLFAFVNGDQ
                     FYLMPTAQDHKRALDGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVKPVLKGMMAEG
                     RPYLGILYCGLILTEDGPKVIEFNARFGDPEAQVILPRLTSDFAQNITDMLEGNTANI
                     TWSDEGVTLGVVLASNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGR
                     VYMLVTTAVTVPAAQEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            44103..44591
                     /gene="purE"
                     /locus_tag="Sez_0031"
                     /db_xref="GeneID:6761674"
     CDS             44103..44591
                     /gene="purE"
                     /locus_tag="Sez_0031"
                     /note="similar to ref|YP_001127629.1| putative
                     phosphoribosylaminoimidazole carboxylase catalytic subunit
                     [Streptococcus pyogenes str. Manfredo]; This subunit can
                     alone transform AIR to CAIR, but in association with purK,
                     which possesses an ATPase activity, an enzyme complex is
                     produced which is capable of converting AIR to CAIR
                     efficiently under physiological condition."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase
                     catalytic subunit PurE"
                     /protein_id="YP_002122431.1"
                     /db_xref="GI:195977187"
                     /db_xref="GeneID:6761674"
                     /translation="MKPIISIIMGSTSDWATMQKTAEILDQFGLAYEKKVISAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGAINAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTNE
                     LN"
     gene            44578..45669
                     /gene="purK"
                     /locus_tag="Sez_0032"
                     /db_xref="GeneID:6760877"
     CDS             44578..45669
                     /gene="purK"
                     /locus_tag="Sez_0032"
                     /note="similar to ref|YP_138587.1|
                     phosphoribosylaminoimidazole carboxylase ATPase subunit
                     [Streptococcus thermophilus LMG 18311]; Possesses an
                     ATPase activity that is dependent on the presence of AIR
                     (aminoimidazole ribonucleotide). The association of purK
                     and purE produces an enzyme complex capable of converting
                     AIR to CAIR efficiently under physiological condition."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase ATPase
                     subunit PurK"
                     /protein_id="YP_002122432.1"
                     /db_xref="GI:195977188"
                     /db_xref="GeneID:6760877"
                     /translation="MSLTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPTADCPASRV
                     SEVIVAPYTDVEALRQLAERCDILTYEFENVDADALDTVVKEEQLPQGTDLLRMSQNR
                     IFEKDFLTNKAGVAVAPYRVVSSSLDLEQLDFSKNYVLKTATGGYDGHGQVVIRTEAD
                     LEKANQLAHSTECVLEEFVSFDREISVIISGNGNEVTVFPVQESSHRNNILSKTIVPA
                     RISEALSAKAQAMAVKIAEQLNLFGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPSIHLHAPAVMLNVLGQHMEQAQAYITENPSAHLHLYGKIE
                     AKHNRKMGHVTVLGGSPDTINEFGLGVDF"
     gene            45679..45903
                     /locus_tag="Sez_0033"
                     /db_xref="GeneID:6760873"
     CDS             45679..45903
                     /locus_tag="Sez_0033"
                     /note="similar to ref|NP_734515.1| hypothetical protein
                     gbs0045 [Streptococcus agalactiae NEM316]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122433.1"
                     /db_xref="GI:195977189"
                     /db_xref="GeneID:6760873"
                     /translation="MIQIIVHAFIENGETGVVEVVFASENSQAISGKMAELQNQYPAD
                     YLAIYDLPLDTDLSQLPHYPSIAIGKEEFE"
     gene            46288..47641
                     /gene="purB"
                     /locus_tag="Sez_0034"
                     /note="adenylosuccinate lyase; unconfirmed disrupted gene,
                     a potential error in the sequence asssembly"
                     /db_xref="GeneID:6761686"
     gene            47940..48854
                     /locus_tag="Sez_0036"
                     /db_xref="GeneID:6761463"
     CDS             47940..48854
                     /locus_tag="Sez_0036"
                     /note="similar to ref|YP_059401.1| Transcriptional
                     regulator [Streptococcus pyogenes MGAS10394]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="YP_002122434.1"
                     /db_xref="GI:195977190"
                     /db_xref="GeneID:6761463"
                     /translation="MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSI
                     PSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELKYLILRTPTYMDDDKLKLREEQF
                     DEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
                     LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSL
                     SIKSNKLEILEKVIVLSQKIILKTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKA
                     CLFAQLTGDQYLEKKLREEWGKDIKRYQ"
     gene            49069..50070
                     /gene="ruvB"
                     /locus_tag="Sez_0037"
                     /db_xref="GeneID:6761475"
     CDS             49069..50070
                     /gene="ruvB"
                     /locus_tag="Sez_0037"
                     /note="similar to ref|NP_734519.1| Holliday junction DNA
                     helicase B [Streptococcus agalactiae NEM316]; The
                     ruvA-ruvB complex in the presence of ATP renatures
                     cruciform structure in supercoiled DNA with palindromic
                     sequence, indicating that it may promote strand exchange
                     reactions in homologous recombination. RuvAB is an
                     helicase that mediates the Holliday junction migration by
                     localized denaturation and reannealing."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction DNA helicase RuvB"
                     /protein_id="YP_002122435.1"
                     /db_xref="GI:195977191"
                     /db_xref="GeneID:6761475"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGPPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMTVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKKH"
     gene            complement(50082..50270)
                     /locus_tag="Sez_0038"
                     /db_xref="GeneID:6760879"
     CDS             complement(50082..50270)
                     /locus_tag="Sez_0038"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122436.1"
                     /db_xref="GI:195977192"
                     /db_xref="GeneID:6760879"
                     /translation="MFFNALSSESTSASLTNHPSPRFTFFPNALIVLVSVAIRLIKLA
                     IDNTKDLTPVKTKESSLT"
     gene            50356..50814
                     /gene="acp1"
                     /locus_tag="Sez_0039"
                     /db_xref="GeneID:6761704"
     CDS             50356..50814
                     /gene="acp1"
                     /locus_tag="Sez_0039"
                     /note="similar to ref|NP_268454.1| putative
                     protein-tyrosine phosphatase [Streptococcus pyogenes M1
                     GAS]; Acts on tyrosine phosphorylated proteins, low-MW
                     aryl phosphates and natural and synthetic acyl phosphates.
                     Isoform 3 does not possess phosphatase activity."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotyrosine protein phosphatase"
                     /protein_id="YP_002122437.1"
                     /db_xref="GI:195977193"
                     /db_xref="GeneID:6761704"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSLDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            50820..51221
                     /locus_tag="Sez_0040"
                     /db_xref="GeneID:6761751"
     CDS             50820..51221
                     /locus_tag="Sez_0040"
                     /note="similar to ref|NP_606371.1| hypothetical protein
                     spyM18_0041 [Streptococcus pyogenes MGAS8232]; Unknown,
                     MORN repeat motif family protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein membrane associated"
                     /protein_id="YP_002122438.1"
                     /db_xref="GI:195977194"
                     /db_xref="GeneID:6761751"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            51218..52998
                     /gene="oatA"
                     /locus_tag="Sez_0041"
                     /note="O-acetyltransferase; unconfirmed disrupted gene, a
                     potential error in the sequence asssembly"
                     /db_xref="GeneID:6761670"
     gene            53419..56061
                     /gene="adh2"
                     /locus_tag="Sez_0043"
                     /db_xref="GeneID:6761652"
     CDS             53419..56061
                     /gene="adh2"
                     /locus_tag="Sez_0043"
                     /note="similar to ref|YP_281403.1| alcohol
                     dehydrogenase/acetaldehyde dehydrogenase (acetylating)
                     [Streptococcus pyogenes MGAS5005]; This enzyme has two
                     NAD(+)-dependent activities:ADH and ACDH. May be a
                     critical enzyme in the fermentative pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="YP_002122439.1"
                     /db_xref="GI:195977195"
                     /db_xref="GeneID:6761652"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPDFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            56329..56535
                     /locus_tag="Sez_0044"
                     /db_xref="GeneID:6761671"
     CDS             56329..56535
                     /locus_tag="Sez_0044"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122440.1"
                     /db_xref="GI:195977196"
                     /db_xref="GeneID:6761671"
                     /translation="MLRLSDELYFLIKQGVIAFLMMVMTLKTFIYQTKTEIMILSDFF
                     QNCLLLIDKEGVKNYTKNVIDYIF"
     gene            56556..57608
                     /gene="adh"
                     /locus_tag="Sez_0045"
                     /db_xref="GeneID:6760792"
     CDS             56556..57608
                     /gene="adh"
                     /locus_tag="Sez_0045"
                     /note="similar to ref|YP_598559.1| Zn-dependent alcohol
                     dehydrogenase [Streptococcus pyogenes MGAS10270]"
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent alcohol dehydrogenases and related
                     dehydrogenases"
                     /protein_id="YP_002122441.1"
                     /db_xref="GI:195977197"
                     /db_xref="GeneID:6760792"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIVAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            57813..58829
                     /gene="adhA"
                     /locus_tag="Sez_0046"
                     /db_xref="GeneID:6760880"
     CDS             57813..58829
                     /gene="adhA"
                     /locus_tag="Sez_0046"
                     /note="similar to ref|NP_663841.1| alcohol dehydrogenase
                     [Streptococcus pyogenes MGAS315]; Preferred specificity is
                     towards 1-propanol."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase I"
                     /protein_id="YP_002122442.1"
                     /db_xref="GI:195977198"
                     /db_xref="GeneID:6760880"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTI"
     gene            59549..61141
                     /locus_tag="Sez_0047"
                     /db_xref="GeneID:6761720"
     CDS             59549..61141
                     /locus_tag="Sez_0047"
                     /note="similar to ref|YP_001034708.1| ABC-type
                     multidrug/protein/lipid transport system (pediocin PA-1
                     exporter), ATPase and permease components, putative
                     [Streptococcus sanguinis SK36]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type multidrug/protein/lipid transport
                     system, ATPase component"
                     /protein_id="YP_002122443.1"
                     /db_xref="GI:195977199"
                     /db_xref="GeneID:6761720"
                     /translation="MKEIVRSHRLLYVIVAFFSVISAFLMTLFSIQLGKILDSISNSS
                     SELLFQIIVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLLREFNEIDTC
                     DRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWRLALVFLLLS
                     IVTVFLSQIPGKLMSKATRYYSEKNNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNT
                     TLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLL
                     NRVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEGDISSISINN
                     LTYQVENRKIFTNFSFEFKKGNTYAIIGPSGVGKTTLAKLILNYYPKHLYDGEIRIDG
                     RNIAEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLNLTNKLKDSLGFDEIFLNK
                     KLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTSNLDPARSKAILDYILSIKNAI
                     IIVITHNQDIKTLEQFDEVICL"
     gene            61312..62433
                     /locus_tag="Sez_0048"
                     /db_xref="GeneID:6761595"
     CDS             61312..62433
                     /locus_tag="Sez_0048"
                     /note="similar to ref|NP_815050.1| HesA/MoeB/ThiF family
                     protein [Enterococcus faecalis V583]"
                     /codon_start=1
                     /transl_table=11
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="YP_002122444.1"
                     /db_xref="GI:195977200"
                     /db_xref="GeneID:6761595"
                     /translation="MNNFFPKWNQDRIVYSWQNDKLRIGADDNDVLEIKGNSIFWSDF
                     ISCCDGNNSIKDIQKLLNIKYNISEEIITEYLDRFSNRNLLEILDNPINQLQDYRSIE
                     SLETYYASEGIGGIKLLKMLGNLKISILGCGGGGSHIALQLAQLGVGRIHLVDHDIIE
                     ENNINRQSMFTFNDVGNYKVDCVAKSIQQRNSKCLVTKSTSKMINVPDVKKEISESDW
                     VFCCMDEAPYIAQRIVNRACYLLKIPSIYCFSQRSAGKLLFCNPNIEDSGCIDCLLSE
                     QDNENFQKLVTTFTTYNRKLVTANILPNILLLTSWVVKRWLDCVIDKNSNVWNMLLRF
                     DFYKYMEEKFQYFSKQDSCPTCAKGPSTSKLWEILKIDE"
     gene            62426..63601
                     /locus_tag="Sez_0049"
                     /db_xref="GeneID:6761636"
     CDS             62426..63601
                     /locus_tag="Sez_0049"
                     /note="similar to ref|YP_196698.1| Hypothetical zinc
                     protease [Ehrlichia ruminantium str. Gardel]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc protease"
                     /protein_id="YP_002122445.1"
                     /db_xref="GI:195977201"
                     /db_xref="GeneID:6761636"
                     /translation="MNKKIIFKGDQDSKFAYFSLMFSAGTAIENTEELGFSHLIEHLL
                     LRSGGEQSLNELFDNNGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTE
                     EELLREKRVVLVELTQYENGSKTEKLVSDNRLIFKNSKWSEDIIGVKENIESVDLKKL
                     YKFYTENIQNGEFQIAISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKN
                     QQVSEISMYIDISKMTTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFP
                     IFYNGLTILKILTRTPEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSY
                     EVKKVEFLKTLCREKLFNIPSWESVTREIEKVSLNELNQFAKDALMQNKQFHIIINC"
     gene            complement(63585..64448)
                     /locus_tag="Sez_0050"
                     /db_xref="GeneID:6760886"
     CDS             complement(63585..64448)
                     /locus_tag="Sez_0050"
                     /note="similar to ref|YP_140611.1| positive
                     transcriptional regulator MutR family [Streptococcus
                     thermophilus CNRZ1066]"
                     /codon_start=1
                     /transl_table=11
                     /product="positive transcriptional regulator, MutR family"
                     /protein_id="YP_002122446.1"
                     /db_xref="GI:195977202"
                     /db_xref="GeneID:6760886"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKIGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISELDNNHQLTNQDISYLSNYLFSVENWGYYETLILGNCC
                     RSLPPKLLFKYTKEALKKGTLYNSIPRNKQSLIQLLLNSLLLMIENDFYEEAIFLNQA
                     SKNLLSNSTYFFELTILLYLEGYLELKFNIHTEKSNSKIEEALKIFNSLNKTIYQNYQ
                     EHFNKYISNLL"
     gene            65062..65361
                     /locus_tag="Sez_0051"
                     /db_xref="GeneID:6760888"
     CDS             65062..65361
                     /locus_tag="Sez_0051"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122447.1"
                     /db_xref="GI:195977203"
                     /db_xref="GeneID:6760888"
                     /translation="MPKNYLSRRVTMKRLKTLCFLATAITLTLAPISTSQTQPQTVYA
                     SAVVIKDYNNGYRYFDENNGQTMRATSFEGRRRSWRDSILDLLERVWNTVVKWLF"
     gene            65600..67075
                     /gene="thnsl"
                     /locus_tag="Sez_0052"
                     /db_xref="GeneID:6760889"
     CDS             65600..67075
                     /gene="thnsl"
                     /locus_tag="Sez_0052"
                     /note="similar to ref|YP_142207.1| threonine synthase
                     [Streptococcus thermophilus CNRZ1066]; Threonine
                     biosynthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase-like protein"
                     /protein_id="YP_002122448.1"
                     /db_xref="GI:195977204"
                     /db_xref="GeneID:6760889"
                     /translation="MYQSTRNAANKVTASQAILGGLADDGGLFTPTSMPVLDLDFEEL
                     KTKSYQEVTKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLELFH
                     GPTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFADVPGTDII
                     VFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAAQQI
                     QLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLAAYYAK
                     EIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVFHLL
                     GNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDHYVL
                     DPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEALEQL
                     ADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            67115..67774
                     /locus_tag="Sez_0053"
                     /db_xref="GeneID:6761791"
     CDS             67115..67774
                     /locus_tag="Sez_0053"
                     /note="similar to ref|YP_059409.1| Na+ driven multidrug
                     efflux pump [Streptococcus pyogenes MGAS10394]; Multidrug
                     efflux pump."
                     /codon_start=1
                     /transl_table=11
                     /product="multi antimicrobial extrusion (MATE) family
                     transporter"
                     /protein_id="YP_002122449.1"
                     /db_xref="GI:195977205"
                     /db_xref="GeneID:6761791"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     R"
     gene            67671..68417
                     /locus_tag="Sez_0054"
                     /db_xref="GeneID:6761693"
     CDS             67671..68417
                     /locus_tag="Sez_0054"
                     /note="similar to ref|YP_059409.1| Na+ driven multidrug
                     efflux pump [Streptococcus pyogenes MGAS10394]; Multidrug
                     efflux pump."
                     /codon_start=1
                     /transl_table=11
                     /product="multi antimicrobial extrusion (MATE) family
                     transporter"
                     /protein_id="YP_002122450.1"
                     /db_xref="GI:195977206"
                     /db_xref="GeneID:6761693"
                     /translation="MLGQLLHHVSLELLFYVTFFLLKKLLNVLLIPLDKEIFSLSLPA
                     AGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMSTATVILVANQL
                     GSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKAQQAGMVVLVFS
                     LLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGVTLNYGLIGVWL
                     ATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            68797..69105
                     /gene="rpsJ"
                     /locus_tag="Sez_0055"
                     /db_xref="GeneID:6761772"
     CDS             68797..69105
                     /gene="rpsJ"
                     /locus_tag="Sez_0055"
                     /note="similar to ref|YP_140348.1| 30S ribosomal protein
                     S10 [Streptococcus thermophilus LMG 18311]; Involved in
                     the binding of tRNA to the ribosomes."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="YP_002122451.1"
                     /db_xref="GI:195977207"
                     /db_xref="GeneID:6761772"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVKIKL"
     gene            69403..70029
                     /gene="rplC"
                     /locus_tag="Sez_0056"
                     /db_xref="GeneID:6761781"
     CDS             69403..70029
                     /gene="rplC"
                     /locus_tag="Sez_0056"
                     /note="similar to ref|YP_140347.1| 50S ribosomal protein
                     L3 [Streptococcus thermophilus LMG 18311]; One of the
                     primary rRNA binding proteins, it binds directly near the
                     3' end of the 23S rRNA, where it nucleates assembly of the
                     50S subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="YP_002122452.1"
                     /db_xref="GI:195977208"
                     /db_xref="GeneID:6761781"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            70054..70677
                     /gene="rplD"
                     /locus_tag="Sez_0057"
                     /db_xref="GeneID:6760700"
     CDS             70054..70677
                     /gene="rplD"
                     /locus_tag="Sez_0057"
                     /note="similar to ref|NP_268461.1| 50S ribosomal protein
                     L4 [Streptococcus pyogenes M1 GAS]; Forms part of the
                     polypeptide exit tunnel."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="YP_002122453.1"
                     /db_xref="GI:195977209"
                     /db_xref="GeneID:6760700"
                     /translation="MANVKLFDQTGKEVSTVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVSADKLLVTKEAISTIEEVLA"
     gene            70725..70973
                     /gene="rplW"
                     /locus_tag="Sez_0058"
                     /db_xref="GeneID:6760678"
     CDS             70725..70973
                     /gene="rplW"
                     /locus_tag="Sez_0058"
                     /note="similar to ref|NP_268462.1| 50S ribosomal protein
                     L23 [Streptococcus pyogenes M1 GAS]; Binds to a specific
                     region on the 23S rRNA."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="YP_002122454.1"
                     /db_xref="GI:195977210"
                     /db_xref="GeneID:6760678"
                     /translation="MYALEEGKYTFEVDTRAHKLLIKQAVEAAFDGVKVASVNTVNVK
                     PKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            70991..71824
                     /gene="rplB"
                     /locus_tag="Sez_0059"
                     /db_xref="GeneID:6760415"
     CDS             70991..71824
                     /gene="rplB"
                     /locus_tag="Sez_0059"
                     /note="similar to ref|NP_268463.1| 50S ribosomal protein
                     L2 [Streptococcus pyogenes M1 GAS]; One of the primary
                     rRNA binding proteins. Required for association of the 30S
                     and 50S subunits to form the 70S ribosome, for tRNA
                     binding and peptide bond formation. It has been suggested
                     to have peptidyltransferase activity; this is somewhat
                     controversial. Makes several contacts with the 16S rRNA in
                     the 70S ribosome."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="YP_002122455.1"
                     /db_xref="GI:195977211"
                     /db_xref="GeneID:6760415"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKIGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLIVRRRNE
                     K"
     gene            71876..72214
                     /gene="rpsS"
                     /locus_tag="Sez_0060"
                     /db_xref="GeneID:6760417"
     CDS             71876..72214
                     /gene="rpsS"
                     /locus_tag="Sez_0060"
                     /note="similar to gb|ABP89047.1| SSU ribosomal protein
                     S19P [Streptococcus suis 05ZYH33]; Protein S19 forms a
                     complex with S13 that binds strongly to the 16S ribosomal
                     RNA."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="YP_002122456.1"
                     /db_xref="GI:195977212"
                     /db_xref="GeneID:6760417"
                     /translation="MSLLSYSSRCGTLFKGENYKMGRSLKKGPFVDEHLMKKVEAQAN
                     DEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKG
                     HAADDKKTRR"
     gene            72230..72574
                     /gene="rplV"
                     /locus_tag="Sez_0061"
                     /db_xref="GeneID:6760823"
     CDS             72230..72574
                     /gene="rplV"
                     /locus_tag="Sez_0061"
                     /note="similar to ref|NP_268465.1| 50S ribosomal protein
                     L22 [Streptococcus pyogenes M1 GAS]; The globular domain
                     of the protein is located near the polypeptide exit tunnel
                     on the outside of the subunit, while an extended
                     beta-hairpin is found that lines the wall of the exit
                     tunnel in the center of the 70S ribosome."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="YP_002122457.1"
                     /db_xref="GI:195977213"
                     /db_xref="GeneID:6760823"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            72587..73240
                     /gene="rpsC"
                     /locus_tag="Sez_0062"
                     /db_xref="GeneID:6760690"
     CDS             72587..73240
                     /gene="rpsC"
                     /locus_tag="Sez_0062"
                     /note="similar to ref|NP_268466.1| 30S ribosomal protein
                     S3 [Streptococcus pyogenes M1 GAS]; Binds the lower part
                     of the 30S subunit head. Binds mRNA in the 70S ribosome,
                     positioning it for translation."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="YP_002122458.1"
                     /db_xref="GI:195977214"
                     /db_xref="GeneID:6760690"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            73244..73657
                     /gene="rplP"
                     /locus_tag="Sez_0063"
                     /db_xref="GeneID:6760414"
     CDS             73244..73657
                     /gene="rplP"
                     /locus_tag="Sez_0063"
                     /note="similar to ref|NP_268467.1| 50S ribosomal protein
                     L16 [Streptococcus pyogenes M1 GAS]; Binds 23S rRNA and is
                     also seen to make contacts with the A and possibly P site
                     tRNAs."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="YP_002122459.1"
                     /db_xref="GI:195977215"
                     /db_xref="GeneID:6760414"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            73667..73873
                     /gene="rpmC"
                     /locus_tag="Sez_0064"
                     /db_xref="GeneID:6760364"
     CDS             73667..73873
                     /gene="rpmC"
                     /locus_tag="Sez_0064"
                     /note="similar to ref|YP_140339.1| 50S ribosomal protein
                     L29 [Streptococcus thermophilus LMG 18311]; One Of The
                     Proteins That Surrounds The Polypeptide Exit Tunnel On The
                     Outside Of The Subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="YP_002122460.1"
                     /db_xref="GI:195977216"
                     /db_xref="GeneID:6760364"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            73901..74161
                     /gene="rpsQ"
                     /locus_tag="Sez_0065"
                     /db_xref="GeneID:6760410"
     CDS             73901..74161
                     /gene="rpsQ"
                     /locus_tag="Sez_0065"
                     /note="similar to ref|YP_821208.1| 30S ribosomal protein
                     S17 [Streptococcus thermophilus LMD-9]; Protein S17 binds
                     specifically to the 5' end of 16S ribosomal RNA."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="YP_002122461.1"
                     /db_xref="GI:195977217"
                     /db_xref="GeneID:6760410"
                     /translation="MERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSKK
                     YKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            74186..74554
                     /gene="rplN"
                     /locus_tag="Sez_0066"
                     /db_xref="GeneID:6761683"
     CDS             74186..74554
                     /gene="rplN"
                     /locus_tag="Sez_0066"
                     /note="similar to ref|NP_268470.1| 50S ribosomal protein
                     L14 [Streptococcus pyogenes M1 GAS]; This protein binds
                     directly to 23S ribosomal RNA."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="YP_002122462.1"
                     /db_xref="GI:195977218"
                     /db_xref="GeneID:6761683"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            74638..74943
                     /gene="rplX"
                     /locus_tag="Sez_0067"
                     /db_xref="GeneID:6761777"
     CDS             74638..74943
                     /gene="rplX"
                     /locus_tag="Sez_0067"
                     /note="similar to ref|YP_140336.1| 50S ribosomal protein
                     L24 [Streptococcus thermophilus LMG 18311]; One of the
                     proteins that surrounds the polypeptide exit tunnel on the
                     outside of the subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="YP_002122463.1"
                     /db_xref="GI:195977219"
                     /db_xref="GeneID:6761777"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            74967..75509
                     /gene="rplE"
                     /locus_tag="Sez_0068"
                     /db_xref="GeneID:6761797"
     CDS             74967..75509
                     /gene="rplE"
                     /locus_tag="Sez_0068"
                     /note="similar to ref|NP_268472.1| 50S ribosomal protein
                     L5 [Streptococcus pyogenes M1 GAS]; This is 1 of the
                     proteins that binds and probably mediates the attachment
                     of the 5S RNA into the large ribosomal subunit, where it
                     forms part of the central protuberance. In the 70S
                     ribosome it contacts protein S13 of the 30S subunit
                     (bridge B1b), connecting the 2 subunits; this bridge is
                     implicated in subunit movement. Contacts the P site tRNA;
                     the 5S rRNA and some of its associated proteins might help
                     stabilize positioning of ribosome-bound tRNAs."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="YP_002122464.1"
                     /db_xref="GI:195977220"
                     /db_xref="GeneID:6761797"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            75525..75710
                     /gene="rpsN"
                     /locus_tag="Sez_0069"
                     /db_xref="GeneID:6760892"
     CDS             75525..75710
                     /gene="rpsN"
                     /locus_tag="Sez_0069"
                     /note="similar to ref|NP_268473.1| Gene info 30S ribosomal
                     protein S14 [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="SSU ribosomal protein S14p (S29e)"
                     /protein_id="YP_002122465.1"
                     /db_xref="GI:195977221"
                     /db_xref="GeneID:6760892"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            76043..76441
                     /gene="rpsH"
                     /locus_tag="Sez_0070"
                     /db_xref="GeneID:6761774"
     CDS             76043..76441
                     /gene="rpsH"
                     /locus_tag="Sez_0070"
                     /note="similar to ref|YP_140333.1| 30S ribosomal protein
                     S8 [Streptococcus thermophilus LMG 18311]; One of the
                     primary rRNA binding proteins, it binds directly to 16S
                     rRNA central domain where it helps coordinate assembly of
                     the platform of the 30S subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="YP_002122466.1"
                     /db_xref="GI:195977222"
                     /db_xref="GeneID:6761774"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            76763..77299
                     /gene="rplF"
                     /locus_tag="Sez_0071"
                     /db_xref="GeneID:6761701"
     CDS             76763..77299
                     /gene="rplF"
                     /locus_tag="Sez_0071"
                     /note="similar to ref|NP_268475.1| 50S ribosomal protein
                     L6 [Streptococcus pyogenes M1 GAS]; This protein binds
                     directly to 23S ribosomal RNA and is located at the
                     aminoacyl-tRNA binding site of the peptidyltransferase
                     center."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="YP_002122467.1"
                     /db_xref="GI:195977223"
                     /db_xref="GeneID:6761701"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            77393..77758
                     /gene="rplR"
                     /locus_tag="Sez_0072"
                     /db_xref="GeneID:6760893"
     CDS             77393..77758
                     /gene="rplR"
                     /locus_tag="Sez_0072"
                     /note="similar to ref|ZP_00365696.1| COG0256: Ribosomal
                     protein L18 [Streptococcus pyogenes M49 591]; Ribosomal
                     L18p/L5e family. This family includes ribosomal proteins
                     from the large subunit. This family includes L18 from
                     bacteria and L5 from eukaryotes. It has been shown that
                     the amino terminal 93 amino acids of the rat 60S ribosomal
                     protein L5 are necessary and sufficient to bind 5S rRNA in
                     vitro. Suggesting that the entire family has a function in
                     rRNA binding."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="YP_002122468.1"
                     /db_xref="GI:195977224"
                     /db_xref="GeneID:6760893"
                     /translation="MKIVISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIY
                     AQVIDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYL
                     YHGRVKALADAARENGLKF"
     gene            77777..78271
                     /gene="rpsE"
                     /locus_tag="Sez_0073"
                     /db_xref="GeneID:6760898"
     CDS             77777..78271
                     /gene="rpsE"
                     /locus_tag="Sez_0073"
                     /note="similar to ref|NP_268477.1| 30S ribosomal protein
                     S5 [Streptococcus pyogenes M1 GAS]; Located at the back of
                     the 30S subunit body where it stabilizes the conformation
                     of the head with respect to the body."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="YP_002122469.1"
                     /db_xref="GI:195977225"
                     /db_xref="GeneID:6760898"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            78286..78468
                     /gene="rpmD"
                     /locus_tag="Sez_0074"
                     /db_xref="GeneID:6760897"
     CDS             78286..78468
                     /gene="rpmD"
                     /locus_tag="Sez_0074"
                     /note="similar to ref|NP_268478.1| 50S ribosomal protein
                     L30 [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="YP_002122470.1"
                     /db_xref="GI:195977226"
                     /db_xref="GeneID:6760897"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            78670..79110
                     /gene="rplO"
                     /locus_tag="Sez_0075"
                     /db_xref="GeneID:6760890"
     CDS             78670..79110
                     /gene="rplO"
                     /locus_tag="Sez_0075"
                     /note="similar to ref|NP_687113.1| 50S ribosomal protein
                     L15 [Streptococcus agalactiae 2603V/R]; Binds to the 23S
                     rRNA."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="YP_002122471.1"
                     /db_xref="GI:195977227"
                     /db_xref="GeneID:6760890"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            79127..80431
                     /gene="secY"
                     /locus_tag="Sez_0076"
                     /db_xref="GeneID:6760896"
     CDS             79127..80431
                     /gene="secY"
                     /locus_tag="Sez_0076"
                     /note="similar to gb|AAT86248.1| Protein translocase
                     subunit secY [Streptococcus pyogenes MGAS10394]; Involved
                     in protein export. Interacts with secA and secE to allow
                     the translocation of proteins across the plasma membrane,
                     by forming part of a channel."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="YP_002122472.1"
                     /db_xref="GI:195977228"
                     /db_xref="GeneID:6760896"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            80472..81224
                     /gene="adk"
                     /locus_tag="Sez_0077"
                     /db_xref="GeneID:6760891"
     CDS             80472..81224
                     /gene="adk"
                     /locus_tag="Sez_0077"
                     /note="similar to ref|ZP_01834380.1| adenylate kinase
                     [Streptococcus pneumoniae SP23-BS72]; This small
                     ubiquitous enzyme is essential for maintenance and cell
                     growth."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase Adk"
                     /protein_id="YP_002122473.1"
                     /db_xref="GI:195977229"
                     /db_xref="GeneID:6760891"
                     /translation="MTIRFTEPWFLSSYCHLKTKTRKTKFPIIFMSKEEKKMNLLIMG
                     LPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTEMGVLAKSYIDKGDLVPDEVTN
                     GIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLKALGLTLDGVINIEVDSASLID
                     RLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDDKPETVKRRLDVNIAQGEPIIK
                     HYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            81288..81560
                     /gene="infA"
                     /locus_tag="Sez_0078"
                     /db_xref="GeneID:6760887"
     CDS             81288..81560
                     /gene="infA"
                     /locus_tag="Sez_0078"
                     /note="similar to ref|YP_279534.1| translation initiation
                     factor IF-1 [Streptococcus pyogenes MGAS6180]; No specific
                     function has so far been attributed to this initiation
                     factor; however, it seems to stimulate more or less all
                     the activities of the other two initiation factors, IF-2
                     and IF-3."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="YP_002122474.1"
                     /db_xref="GI:195977230"
                     /db_xref="GeneID:6760887"
                     /translation="MLPLCSEDIKSKFRGYFCVAKEDVIEIEGKVVETMPNAMFTVEL
                     ENGHQILATVSGKIRKNYIRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            81586..81702
                     /gene="rpmJ"
                     /locus_tag="Sez_0079"
                     /db_xref="GeneID:6760361"
     CDS             81586..81702
                     /gene="rpmJ"
                     /locus_tag="Sez_0079"
                     /note="similar to ref|NP_268483.1| Gene info 50S ribosomal
                     protein L36 [Streptococcus pyogenes M1 GAS]; Ribosomal
                     large subunit protein."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="YP_002122475.1"
                     /db_xref="GI:195977231"
                     /db_xref="GeneID:6760361"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            81720..82085
                     /gene="rpsM"
                     /locus_tag="Sez_0080"
                     /db_xref="GeneID:6760681"
     CDS             81720..82085
                     /gene="rpsM"
                     /locus_tag="Sez_0080"
                     /note="similar to ref|YP_001197465.1| 30S ribosomal
                     protein S13 [Streptococcus suis 05ZYH33]; Located at the
                     top of the head of the 30S subunit, it contacts several
                     helices of the 16S rRNA. In the 70S ribosome it contacts
                     the 23S rRNA (bridge B1a) and protein L5 of the 50S
                     subunit (bridge B1b), connecting the 2 subunits; these
                     bridges are implicated in subunit movement. Contacts the
                     tRNAs in the A and P- sites."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="YP_002122476.1"
                     /db_xref="GI:195977232"
                     /db_xref="GeneID:6760681"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            82103..82486
                     /gene="rpsK"
                     /locus_tag="Sez_0081"
                     /db_xref="GeneID:6760849"
     CDS             82103..82486
                     /gene="rpsK"
                     /locus_tag="Sez_0081"
                     /note="similar to ref|NP_606402.1| 30S ribosomal protein
                     S11 [Streptococcus pyogenes MGAS8232]; Located on the
                     platform of the 30S subunit, it bridges several disparate
                     RNA helices of the 16S rRNA. Forms part of the
                     Shine-Dalgarno cleft in the 70S ribosome."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="YP_002122477.1"
                     /db_xref="GI:195977233"
                     /db_xref="GeneID:6760849"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            82533..83471
                     /gene="rpoA"
                     /locus_tag="Sez_0082"
                     /db_xref="GeneID:6760512"
     CDS             82533..83471
                     /gene="rpoA"
                     /locus_tag="Sez_0082"
                     /note="similar to ref|NP_268486.1| DNA-directed RNA
                     polymerase subunit alpha [Streptococcus pyogenes M1 GAS];
                     DNA-dependent RNA polymerase catalyzes the transcription
                     of DNA into RNA using the four ribonucleoside
                     triphosphates as substrates."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase alpha chain"
                     /protein_id="YP_002122478.1"
                     /db_xref="GI:195977234"
                     /db_xref="GeneID:6760512"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            83486..83872
                     /gene="rplQ"
                     /locus_tag="Sez_0083"
                     /db_xref="GeneID:6761745"
     CDS             83486..83872
                     /gene="rplQ"
                     /locus_tag="Sez_0083"
                     /note="similar to ref|NP_268487.1| 50S ribosomal protein
                     L17 [Streptococcus pyogenes M1 GAS]; Unknown, structural
                     constituent of ribosome."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="YP_002122479.1"
                     /db_xref="GI:195977235"
                     /db_xref="GeneID:6761745"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            85192..85986
                     /locus_tag="Sez_0084"
                     /db_xref="GeneID:6760894"
     CDS             85192..85986
                     /locus_tag="Sez_0084"
                     /note="similar to ref|YP_850136.1| hypothetical protein
                     lwe1939 [Listeria welshimeri serovar 6b str. SLCC5334]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122480.1"
                     /db_xref="GI:195977236"
                     /db_xref="GeneID:6760894"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQASLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYGREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     HLGDYVYDPDVLAKGVAISHPWIKTGYTMSKHFGKAVSKDYTKASF"
     gene            85983..86759
                     /locus_tag="Sez_0085"
                     /db_xref="GeneID:6761755"
     CDS             85983..86759
                     /locus_tag="Sez_0085"
                     /note="similar to ref|XP_597510.3| Gene info PREDICTED:
                     similar to olfactory receptor MOR123-1 [Bos taurus]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122481.1"
                     /db_xref="GI:195977237"
                     /db_xref="GeneID:6761755"
                     /translation="MSYGKAGKRASDDLNLAWRDIRNLARQKHWAWYERLGHKWKKGS
                     FSQLLNTFQKTILKKISDFKAFGKYSIKQISTIVGKVTDPIKSSIETLGKHIKNSRLF
                     NKVRWIGKAAKATGWTSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGP
                     IEGAIVGSALSGPIGAMLGFIGGTINTLWGIAAPDSRDKAFSWGQARLDDAYDLIAQT
                     DLGKGTYHAKERVKGHIGRAIVRTWDFVSQSFGKGVGYDS"
     gene            86749..87438
                     /locus_tag="Sez_0086"
                     /db_xref="GeneID:6761804"
     CDS             86749..87438
                     /locus_tag="Sez_0086"
                     /note="similar to gb|EDK97023.1| Gene info
                     phosphoinositide-3-kinase, class 3, isoform CRA_c [Mus
                     musculus]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122482.1"
                     /db_xref="GI:195977238"
                     /db_xref="GeneID:6761804"
                     /translation="MTVKDQFFSGTFEQSKKIVSKSILTEEGAQIGVFSSMSLWKRIT
                     GLMMLPLFAISYGVGVVLPEHFQQSTEGVQAISLAAIEIIARLGQFSRYFIICFVCMS
                     VGLIISNILPKPNYAYQLLYGNVTLTILSITTTISVFPLTAGLTIAAFGWIGFLPQLL
                     LCLYLWKLCVIDKCQQLRTAIYQESTTAPDWGSKLISFIKTYGGILLGLSILNRWTLN
                     LGELVKDPPVC"
     gene            87471..87623
                     /locus_tag="Sez_0087"
                     /db_xref="GeneID:6761689"
     CDS             87471..87623
                     /locus_tag="Sez_0087"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122483.1"
                     /db_xref="GI:195977239"
                     /db_xref="GeneID:6761689"
                     /translation="MFLMLFALGQALKNTIIAYYFFRYQKEYRKHFNISDEQWYGKWR
                     SKILSK"
     gene            87644..87937
                     /locus_tag="Sez_0088"
                     /db_xref="GeneID:6760437"
     CDS             87644..87937
                     /locus_tag="Sez_0088"
                     /note="similar to ref|YP_001449395.1| hypothetical protein
                     SGO_0073 [Streptococcus gordonii str. Challis substr.
                     CH1]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122484.1"
                     /db_xref="GI:195977240"
                     /db_xref="GeneID:6760437"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
     gene            88458..89792
                     /locus_tag="Sez_1983"
                     /note="16S RNA2"
                     /db_xref="GeneID:6760436"
     rRNA            88458..89792
                     /locus_tag="Sez_1983"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:6760436"
     gene            89986..90063
                     /locus_tag="Sez_1984"
                     /note="tRNA_19"
                     /db_xref="GeneID:6761063"
     tRNA            89986..90063
                     /locus_tag="Sez_1984"
                     /product="tRNA-Ala"
                     /note="anticodon TGC"
                     /db_xref="GeneID:6761063"
     gene            90321..93218
                     /locus_tag="Sez_1985"
                     /note="23S RNA2"
                     /db_xref="GeneID:6761040"
     rRNA            90321..93218
                     /locus_tag="Sez_1985"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:6761040"
     gene            93305..93420
                     /locus_tag="Sez_1986"
                     /note="5S RNA2"
                     /db_xref="GeneID:6761054"
     rRNA            93305..93420
                     /locus_tag="Sez_1986"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:6761054"
     gene            93466..93541
                     /locus_tag="Sez_1987"
                     /note="tRNA_20"
                     /db_xref="GeneID:6761052"
     tRNA            93466..93541
                     /locus_tag="Sez_1987"
                     /product="tRNA-Val"
                     /note="anticodon TAC"
                     /db_xref="GeneID:6761052"
     gene            93543..93618
                     /locus_tag="Sez_1988"
                     /note="tRNA_21"
                     /db_xref="GeneID:6761033"
     tRNA            93543..93618
                     /locus_tag="Sez_1988"
                     /product="tRNA-Gly"
                     /note="anticodon TCC"
                     /db_xref="GeneID:6761033"
     gene            93643..93721
                     /locus_tag="Sez_1989"
                     /note="tRNA_22"
                     /db_xref="GeneID:6761049"
     tRNA            93643..93721
                     /locus_tag="Sez_1989"
                     /product="tRNA-Ile"
                     /note="anticodon GAT"
                     /db_xref="GeneID:6761049"
     gene            93729..93805
                     /locus_tag="Sez_1990"
                     /note="tRNA_23"
                     /db_xref="GeneID:6761039"
     tRNA            93729..93805
                     /locus_tag="Sez_1990"
                     /product="tRNA-Glu"
                     /note="anticodon TTC"
                     /db_xref="GeneID:6761039"
     gene            93812..93904
                     /locus_tag="Sez_1991"
                     /note="tRNA_24"
                     /db_xref="GeneID:6761216"
     tRNA            93812..93904
                     /locus_tag="Sez_1991"
                     /product="tRNA-Ser"
                     /note="anticodon TGA"
                     /db_xref="GeneID:6761216"
     gene            93912..93990
                     /locus_tag="Sez_1992"
                     /note="tRNA_25"
                     /db_xref="GeneID:6761027"
     tRNA            93912..93990
                     /locus_tag="Sez_1992"
                     /product="tRNA-Met"
                     /note="anticodon CAT"
                     /db_xref="GeneID:6761027"
     gene            94010..94087
                     /locus_tag="Sez_1993"
                     /note="tRNA_26"
                     /db_xref="GeneID:6761128"
     tRNA            94010..94087
                     /locus_tag="Sez_1993"
                     /product="tRNA-Phe"
                     /note="anticodon GAA"
                     /db_xref="GeneID:6761128"
     gene            94102..94187
                     /locus_tag="Sez_1994"
                     /note="tRNA_27"
                     /db_xref="GeneID:6761187"
     tRNA            94102..94187
                     /locus_tag="Sez_1994"
                     /product="tRNA-Tyr"
                     /note="anticodon GTA"
                     /db_xref="GeneID:6761187"
     gene            94190..94263
                     /locus_tag="Sez_1995"
                     /note="tRNA_28"
                     /db_xref="GeneID:6760494"
     tRNA            94190..94263
                     /locus_tag="Sez_1995"
                     /product="tRNA-Trp"
                     /note="anticodon CCA"
                     /db_xref="GeneID:6760494"
     gene            94271..94348
                     /locus_tag="Sez_1996"
                     /note="tRNA_29"
                     /db_xref="GeneID:6760590"
     tRNA            94271..94348
                     /locus_tag="Sez_1996"
                     /product="tRNA-His"
                     /note="anticodon GTG"
                     /db_xref="GeneID:6760590"
     gene            94352..94428
                     /locus_tag="Sez_1997"
                     /note="tRNA_30"
                     /db_xref="GeneID:6760416"
     tRNA            94352..94428
                     /locus_tag="Sez_1997"
                     /product="tRNA-Gln"
                     /note="anticodon TTG"
                     /db_xref="GeneID:6760416"
     gene            94443..94529
                     /locus_tag="Sez_1998"
                     /note="tRNA_31"
                     /db_xref="GeneID:6760758"
     tRNA            94443..94529
                     /locus_tag="Sez_1998"
                     /product="tRNA-Leu"
                     /note="anticodon CAA"
                     /db_xref="GeneID:6760758"
     gene            complement(94623..95756)
                     /gene="int"
                     /locus_tag="Sez_0089"
                     /db_xref="GeneID:6760848"
     CDS             complement(94623..95756)
                     /gene="int"
                     /locus_tag="Sez_0089"
                     /note="similar to ref|YP_001197470.1| hypothetical protein
                     SSU05_0100 [Streptococcus suis 05ZYH33]; Site-specific DNA
                     recombination."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="YP_002122485.1"
                     /db_xref="GI:195977241"
                     /db_xref="GeneID:6760848"
                     /translation="MTVKKAKNGTWTVDISDGFHPVTKKRIRIIRKGFKTKKEALELE
                     QYIRVVELKEKRFDFLVTTDMLFDILEEEDRQNNRKISYISTQRNNYERHIKPYFINT
                     NLNKLSYEHIFEFREYLKIKPKKQNDSSTLSHNTVNKIMILLKKIFDTGVRKSLIDKN
                     PVENLRKLPISKPTIKFWSVEEFNEFRKLITSDEISYDLFFTIAFFTGMRLGEILALN
                     WYDINLITNTIHITKTAYFVHGTNHINSTKTRAGTRHITINHKLARMLGDWKEKQSDL
                     LKEFTTDTESLQVIQSTPLPITKNMIDKKFKQILARNNYLKKIRIHDLRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKTLANKLDDIF"
     gene            complement(95746..95952)
                     /locus_tag="Sez_0090"
                     /db_xref="GeneID:6762181"
     CDS             complement(95746..95952)
                     /locus_tag="Sez_0090"
                     /note="similar to ref|YP_001197471.1| hypothetical protein
                     SSU05_0101 [Streptococcus suis 05ZYH33]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122486.1"
                     /db_xref="GI:195977242"
                     /db_xref="GeneID:6762181"
                     /translation="MIATVNKNDLVALGFSEGTSKRIIRQGKELLIARGFRVYQNKRV
                     GTIPASIATELLGFDVSLGAHHDS"
     gene            complement(96013..96843)
                     /locus_tag="Sez_0091"
                     /db_xref="GeneID:6760634"
     CDS             complement(96013..96843)
                     /locus_tag="Sez_0091"
                     /note="similar to ref|YP_001197472.1| hypothetical protein
                     SSU05_0102 [Streptococcus suis 05ZYH33]; Unknown, COG2946
                     putative phage replication protein RstA."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Cro/CI family"
                     /protein_id="YP_002122487.1"
                     /db_xref="GI:195977243"
                     /db_xref="GeneID:6760634"
                     /translation="MGVFVELKGQGCRQYEEFLDGNENNWIALIGRLYQYSVNFTRLD
                     IAHDIFDGSLDVQRVYDYCKKGLCISKAKHFEYHEKSVLENGERVGETVAIGSRGNQQ
                     WCIYNKRMEQLSKQELVEYPSWIRAELRCWQDKANIIAEQLFLKRPLSSIYFEAINGH
                     YRFVKPNATDTNRWRRKKVKWWLDYLKTENQTVLSVERTKPTLRQSEAWTEKQVAKTL
                     AKVYTAKYQAYDVQKAEDYIQGLLKEGLSRLTDNDEKDIEQYIREQKSSPLWGQKKTT"
     gene            complement(97034..97441)
                     /locus_tag="Sez_0092"
                     /db_xref="GeneID:6760902"
     CDS             complement(97034..97441)
                     /locus_tag="Sez_0092"
                     /note="similar to ref|YP_001197473.1| hypothetical protein
                     SSU05_0103 [Streptococcus suis 05ZYH33]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122488.1"
                     /db_xref="GI:195977244"
                     /db_xref="GeneID:6760902"
                     /translation="MTDTTLKIGQLDLDMTQFEVPKNIVILSAKVNNRYNEVNGEKIK
                     TEEVTKITCTALDADKVKVLTEMGISTDDLKAINLEIVGNVDKVAMLAQNESLLNVPI
                     ELVKPKVRLAWNMARSNWAGVKLVCEDIKILGA"
     gene            complement(97730..99139)
                     /locus_tag="Sez_0093"
                     /db_xref="GeneID:6760633"
     CDS             complement(97730..99139)
                     /locus_tag="Sez_0093"
                     /note="similar to ref|YP_893172.1| FtsK/SpoIIIE family
                     protein [Bacillus thuringiensis str. Al Hakam]; Unknown,
                     COG1674 DNA segregation ATPase FtsK/SpoIIIE and related
                     proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE family protein"
                     /protein_id="YP_002122489.1"
                     /db_xref="GI:195977245"
                     /db_xref="GeneID:6760633"
                     /translation="MRVRKKRVLMMEQIIKKISSLWSKQRLRTVKPNLYIPIIYSKII
                     SRYFYCVFAVLILASVLLFQENIISSIIGIFFLGMFYLIFRFWRKFQQIYLNGINYNL
                     QYMIVSNKFYDSQVVNGREEITNYLVLKYRETELNIEIYAMKYGDKYNDLASNLGSLL
                     SSSLSLELGEMTETISQVRYIFPKFAEMRLTWEDTLLTNNINVSEMVSWQFGSPPHVL
                     LAGSTKSGKTVMIENLVAQYLTLGAEIKLLDPKKGELSWLVGRKLEDRLGYKVVYNSP
                     FQIAGALREAVEEMNRRFQVMADNPDTYISKGKVLSWAEVKGNYPLVIVLDEGIAFKT
                     EAETTKEGKQAYQEAMSNLGSLLVKSRQASIEVIVGLQRASSDFIPTYMRQNFGVALL
                     LGSTTSDLDSCRMMFSSQDIDYKTCDIGTGYIQIDGVIPQPRYVEVPFKSDELDFEEY
                     FDRACERYWRIRNNYGLSD"
     gene            complement(99857..100225)
                     /locus_tag="Sez_0094"
                     /db_xref="GeneID:6762254"
     CDS             complement(99857..100225)
                     /locus_tag="Sez_0094"
                     /note="similar to ref|NP_073692.1| tail protein [Bacillus
                     phage GA-1]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122490.1"
                     /db_xref="GI:195977246"
                     /db_xref="GeneID:6762254"
                     /translation="MRLSKEGRVVLEELKLEYLKHGEVKTSGLILDEIFEYFKSSFKN
                     VNWKLVQNKPEFDEILADYTSVNPTTLNLSEETINTMYEIRDHFNKVLDMKRTVYRSF
                     IIRMILKAYKLEKQSTNIYL"
     gene            complement(100620..101180)
                     /locus_tag="Sez_0095"
                     /note="IS1167"
                     /db_xref="GeneID:6760632"
     CDS             complement(100620..101180)
                     /locus_tag="Sez_0095"
                     /note="similar to ref|ZP_01829310.1| IS1167, transposase
                     [Streptococcus pneumoniae SP18-BS74]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS1167"
                     /protein_id="YP_002122491.1"
                     /db_xref="GI:195977247"
                     /db_xref="GeneID:6760632"
                     /translation="MSGSYIPLIKILFPKAKIVLDRFHIVQHMSRALKYYWRLIQKDS
                     RKLSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIFLALNITKEKTTFVSSRA"
     gene            complement(101346..101813)
                     /locus_tag="Sez_0096"
                     /db_xref="GeneID:6760903"
     CDS             complement(101346..101813)
                     /locus_tag="Sez_0096"
                     /note="similar to ref|ZP_01829310.1| IS1167, transposase
                     [Streptococcus pneumoniae SP18-BS74]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS1193D-like"
                     /protein_id="YP_002122492.1"
                     /db_xref="GI:195977248"
                     /db_xref="GeneID:6760903"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     HCRGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEMVRQKITQLLLNREALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLS"
     gene            complement(101824..102006)
                     /locus_tag="Sez_0097"
                     /note="transposase fragment; similar to ref|YP_060356.1|
                     Transposase [Streptococcus pyogenes MGAS10394]"
                     /db_xref="GeneID:6760630"
     gene            complement(102187..103392)
                     /locus_tag="Sez_0098"
                     /db_xref="GeneID:6760905"
     CDS             complement(102187..103392)
                     /locus_tag="Sez_0098"
                     /note="similar to ref|YP_078429.1| Major facilitator
                     superfamily [Bacillus licheniformis ATCC 14580]; Unknown,
                     COG0477 Permeases of the major facilitator superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux protein, putative"
                     /protein_id="YP_002122493.1"
                     /db_xref="GI:195977249"
                     /db_xref="GeneID:6760905"
                     /translation="MQEDIFTNMTHKDLKRQLNAFKTYVGLYVSRYDFCRLFLGRLIS
                     NCGDSIYTLVLSWYILETTNSAWYVGVLNFLIFIPNTFSFIFGKKIDSHPKKNLLVIL
                     EWAQLLAVLGIILGMSLREIHASLSLTIILTCVFLASMVGLNTYTVQDALVPKLIPTK
                     DLAKAEMYMSVAYNGTDYVFTAVSGFLLSVISYIPLLFIDIVTFLSSILFFRRIEFQE
                     IIEQTNERTDFLSGLRFIWHNKVVLAITLGGAIANFLFAGLNVYQLLIAREVGDSTFY
                     GLLVSASAIGTLVGTTLGANLVLQRLSVGKAFWLATALFGTGIGFTALFRNSFSLLLI
                     WFLSCLFLGVTHVTQKPILQTEIPDEHLGEVFSAFYTVTIPTLALGSLILVSLLYFSN
                     KTLRQYDIS"
     gene            103744..105030
                     /gene="sclZ.1"
                     /locus_tag="Sez_0099"
                     /db_xref="GeneID:6760629"
     CDS             103744..105030
                     /gene="sclZ.1"
                     /locus_tag="Sez_0099"
                     /note="similar to gb|ABA41499.1| collagen-like protein I
                     [Streptococcus equi subsp. equi]; Possible adhesin, has a
                     collagen-structural-motif domain composed of 83
                     Gly-Xaa-Yaa repeats that in part form 22 GDQ-GQK-GER
                     repeats."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein SclZ.1"
                     /protein_id="YP_002122494.1"
                     /db_xref="GI:195977250"
                     /db_xref="GeneID:6760629"
                     /translation="MRSKKTSIRLVQKYGICSAVVALATIASLGTAGAVHAEAPEYPK
                     TTEFSMGVQPYSVFRKGFETYAEKLKKHLEYRLTEFQKRQEELEERGQQSSGKPGPVG
                     PKGQTGDAGPRGPVGPKGEKGEDGRDGQPGPKGPVGPKGQTGDQGQKGERGDQGQKGE
                     RGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQ
                     GQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKG
                     ERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGDQGQKGERGD
                     QGQKGERGDQRPNSDQEKGSKPSAPKAPEKAPAPKAPRALEKSAHTKKSVSSAQKGIL
                     PATGETNHPFFTLAALSIIASAGRLALKEKKNKISY"
     gene            105157..106308
                     /gene="sclZ.2"
                     /locus_tag="Sez_0100"
                     /db_xref="GeneID:6762225"
     CDS             105157..106308
                     /gene="sclZ.2"
                     /locus_tag="Sez_0100"
                     /note="similar to gb|ABA41497.1| collagen-like protein G
                     [Streptococcus equi subsp. equi]; Possible adhesin, has a
                     collagen-structural-motif domain composed of 67
                     Gly-Xaa-Yaa repeats."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein SclZ.2"
                     /protein_id="YP_002122495.1"
                     /db_xref="GI:195977251"
                     /db_xref="GeneID:6762225"
                     /translation="MTNKVNHHKVVRRSGLCSVVLALAVTVGLGTDREVKADVGVPSY
                     PNTNVFKGAHWTVLDERLADYHQELEEYLSFKFNVLSSRMNGLDKKIKENAERPGPPG
                     PAGPKGDTGPIGPVGPTGPKGDKGKDGQDGKPGLPGAQGPKGDTGPIGPKGDKGDPGL
                     KGDKGAPGPKGDTGPIGPKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDK
                     GEQGLKGDKGDPGLKGDKGEQGLKGDKGEQGLKGDKGDPGLKGDKGDPGLKGDKGDPG
                     LKGDKGDPGQHGEKGEQQPKGEQGKDTKPSAPKAPEQSPVPQAPKSSEQPASPKAPVP
                     QSAPSKSAAPTSKKAVLPATGEASHPFFSLAALGVIASAGLLTLKRKNN"
     gene            106820..107344
                     /locus_tag="Sez_0101"
                     /db_xref="GeneID:6760628"
     CDS             106820..107344
                     /locus_tag="Sez_0101"
                     /note="similar to ref|ZP_01372633.1| NUDIX hydrolase
                     [Desulfitobacterium hafniense DCB-2]; Catalyzes The
                     1,3-Allylic Rearrangement Of The Homoallylic Substrate
                     Isopentenyl (Ipp) To Its Highly Electrophilic Allylic
                     Isomer, Dimethylallyl Diphosphate (Dmapp)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative nudix hydrolase"
                     /protein_id="YP_002122496.1"
                     /db_xref="GI:195977252"
                     /db_xref="GeneID:6760628"
                     /translation="MVEYWDVYTMNRLKTGRVMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPGYWDITVGGSALAGETSQEAVMRELKEELGLALDLAGVRPHFSI
                     TFDNGFDDTFLVLQAVDVTKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            107558..108409
                     /gene="ispE"
                     /locus_tag="Sez_0102"
                     /db_xref="GeneID:6762145"
     CDS             107558..108409
                     /gene="ispE"
                     /locus_tag="Sez_0102"
                     /note="similar to ref|NP_722294.1|
                     4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
                     [Streptococcus mutans UA159]; Catalyzes the
                     phosphorylation of the position 2 hydroxy group of
                     4-diphosphocytidyl-2C-methyl-D-erythritol."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2-C-methyl-D-erythritol
                     kinase"
                     /protein_id="YP_002122497.1"
                     /db_xref="GI:195977253"
                     /db_xref="GeneID:6762145"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            108479..108922
                     /gene="adcR"
                     /locus_tag="Sez_0103"
                     /db_xref="GeneID:6760627"
     CDS             108479..108922
                     /gene="adcR"
                     /locus_tag="Sez_0103"
                     /note="similar to ref|YP_059444.1| High-affinity zinc
                     uptake system ATP-binding protein [Streptococcus pyogenes
                     MGAS10394]; Unknown, COG1846 Transcriptional regulators."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor AdcR for
                     Zn(2+)-responsive expression"
                     /protein_id="YP_002122498.1"
                     /db_xref="GI:195977254"
                     /db_xref="GeneID:6760627"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFSEELEG"
     gene            108941..109645
                     /gene="znuC"
                     /locus_tag="Sez_0104"
                     /db_xref="GeneID:6762252"
     CDS             108941..109645
                     /gene="znuC"
                     /locus_tag="Sez_0104"
                     /note="similar to ref|YP_059444.1| High-affinity zinc
                     uptake system ATP-binding protein [Streptococcus pyogenes
                     MGAS10394]; Part of the ATP-driven transport system for
                     zinc."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter, ATP-binding protein ZnuC"
                     /protein_id="YP_002122499.1"
                     /db_xref="GI:195977255"
                     /db_xref="GeneID:6762252"
                     /translation="MENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKSTLIKAT
                     LGILKPRAGQVTIAKQNSHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYPRSGWF
                     TRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFVLDEPT
                     TGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLPWRCFN
                     IHDAEADESKGGSFHA"
     gene            109614..110447
                     /gene="znuB"
                     /locus_tag="Sez_0105"
                     /db_xref="GeneID:6760626"
     CDS             109614..110447
                     /gene="znuB"
                     /locus_tag="Sez_0105"
                     /note="similar to ref|YP_279546.1| high-affinity zinc
                     uptake system membrane protein [Streptococcus pyogenes
                     MGAS6180]; Part of an ATP-driven transport system for
                     zinc."
                     /codon_start=1
                     /transl_table=11
                     /product="Zinc ABC transporter inner membrane permease
                     protein ZnuB"
                     /protein_id="YP_002122500.1"
                     /db_xref="GI:195977256"
                     /db_xref="GeneID:6760626"
                     /translation="MRAKEGHSMLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQ
                     SLLSDTLSHVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAIL
                     MSLGLAISLIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFIIALIILALTILFIR
                     PMYILTFDEDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAM
                     RLGKNFKSVIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIIIFLMVNLLSFIRK
                     T"
     gene            complement(110629..111885)
                     /gene="tyrS"
                     /locus_tag="Sez_0106"
                     /db_xref="GeneID:6760906"
     CDS             complement(110629..111885)
                     /gene="tyrS"
                     /locus_tag="Sez_0106"
                     /note="similar to ref|NP_663877.1| tyrosyl-tRNA synthetase
                     [Streptococcus pyogenes MGAS315]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosyl-tRNA synthetase TyrS"
                     /protein_id="YP_002122501.1"
                     /db_xref="GI:195977257"
                     /db_xref="GeneID:6760906"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTVNYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            111990..114290
                     /gene="pbpZ"
                     /locus_tag="Sez_0107"
                     /db_xref="GeneID:6760625"
     CDS             111990..114290
                     /gene="pbpZ"
                     /locus_tag="Sez_0107"
                     /note="similar to ref|NP_663878.1| putative
                     penicillin-binding protein 1b [Streptococcus pyogenes
                     MGAS315]; CSynthesis and cross-linking of nascent
                     peptidoglycan glycan strands."
                     /codon_start=1
                     /transl_table=11
                     /product="multimodular transpeptidase-transglycosylase"
                     /protein_id="YP_002122502.1"
                     /db_xref="GI:195977258"
                     /db_xref="GeneID:6760625"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VASDAISDNIKKAIVSTEDDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSAEDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKSIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISVGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            114552..118118
                     /gene="rpoB"
                     /locus_tag="Sez_0108"
                     /db_xref="GeneID:6762262"
     CDS             114552..118118
                     /gene="rpoB"
                     /locus_tag="Sez_0108"
                     /note="similar to ref|NP_663879.1| DNA-directed RNA
                     polymerase subunit beta [Streptococcus pyogenes MGAS315];
                     DNA-dependent RNA polymerase catalyzes the transcription
                     of DNA into RNA using the four ribonucleoside
                     triphosphates as substrates."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase beta chain RpoB"
                     /protein_id="YP_002122503.1"
                     /db_xref="GI:195977259"
                     /db_xref="GeneID:6762262"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            118236..121844
                     /gene="rpoC"
                     /locus_tag="Sez_0109"
                     /db_xref="GeneID:6760624"
     CDS             118236..121844
                     /gene="rpoC"
                     /locus_tag="Sez_0109"
                     /note="similar to ref|YP_601585.1| DNA-directed RNA
                     polymerase subunit beta' [Streptococcus pyogenes
                     MGAS10750]; DNA-dependent RNA polymerase catalyzes the
                     transcription of DNA into RNA using the four
                     ribonucleoside triphosphates as substrates."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase beta' chain RpoC"
                     /protein_id="YP_002122504.1"
                     /db_xref="GI:195977260"
                     /db_xref="GeneID:6760624"
                     /translation="MQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFG
                     PTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIP
                     SRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQEYGHGSFIA
                     KMGAEAIQDLLKRVDLATEIAELKEELKTATGQKRIKAVRRLDVLDAFNKSGNKPEWM
                     ILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNE
                     KRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRS
                     VIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAREFAGNVKAAKRMVERGDERIWDI
                     LEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIH
                     VPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIF
                     KDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKPWKDSQRHKIMVTTVGKILFNDIMPED
                     LPYLQEPNNANLTEGTPDKYFLEPGQNIQEVIDSLPLNVPFKKKNLGNIIAETFKRFR
                     TTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVEEINKAFRRG
                     LMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMR
                     GLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVD
                     VAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHPETGEVLIGA
                     DQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTI
                     AAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGTVI
                     EIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKHLLE
                     VRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLM
                     DIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIR
                     GKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAINEVEVIEGAEATEEPAIIEE"
     gene            122411..122965
                     /locus_tag="Sez_0110"
                     /db_xref="GeneID:6762273"
     CDS             122411..122965
                     /locus_tag="Sez_0110"
                     /note="similar to ref|ZP_01803959.1| hypothetical protein
                     CdifQ_04001361 [Clostridium difficile QCD-32g58]; Unknown,
                     Gene is flanked 5' and 3' by a 51 nt direct repeat
                     (aggagctagtcttagctccttttatcatgctaaaatcattagattaattgg) and
                     small ORFs with similarity to IS1193D."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical secreted protein"
                     /protein_id="YP_002122505.1"
                     /db_xref="GI:195977261"
                     /db_xref="GeneID:6762273"
                     /translation="MRIKKVIYSSIAALAILTYGTISANADASISEIDQTEVITILKS
                     DGYLNIDEGTQEVTITEKYKQAVLSSIDLDRQEAIFTENSVTIRDIFSPRSFTGVNKI
                     VFTWKGYDLYLDSTNANRLSALGWGSAALSGLIPDPIVSKVLAAALGVVSASISYANA
                     AGRGVIVAFVGTFPRGVIHWVASQ"
     gene            123518..124576
                     /gene="alr"
                     /locus_tag="Sez_0111"
                     /db_xref="GeneID:6760623"
     CDS             123518..124576
                     /gene="alr"
                     /locus_tag="Sez_0111"
                     /note="similar to ref|NP_736373.1| hypothetical protein
                     gbs1940 [Streptococcus agalactiae NEM316]; Alanine
                     racemase catalyses the pyridoxal-dependent conversion of
                     L-alanine into D-alanine, a key component of bacterial
                     peptidoglycan."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase Alr"
                     /protein_id="YP_002122506.1"
                     /db_xref="GI:195977262"
                     /db_xref="GeneID:6760623"
                     /translation="MIELMTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYE
                     PLHFFLKSFLGRMAVPYFLICTAFFLKGRLREANREKQYFKQMLKTYLFWSLIYFPYA
                     YAFFESLHLPKHYLPLGLCLALGYFGMCYHLWYIPALLLGWVLVQLSLKTFGQKVTLI
                     IVAGLYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHF
                     SSVLFSQRYMKKAALCLTLLTLESLLIYHHQGLDKNFFLLSALFTTFLFNASVRTSLL
                     SKYSLAKLKKLSYYYFFLHPMFIESSLFLLKPYQLAPATKGKLVFLMTLLATHLCSEG
                     LMLLVRSQAHAKAYLRRQ"
     gene            124637..125002
                     /locus_tag="Sez_0112"
                     /db_xref="GeneID:6762246"
     CDS             124637..125002
                     /locus_tag="Sez_0112"
                     /note="similar to ref|NP_268497.1| putative DNA binding
                     protein [Streptococcus pyogenes M1 GAS]; Unknown, COG4699:
                     Uncharacterized protein conserved in bacteria."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122507.1"
                     /db_xref="GI:195977263"
                     /db_xref="GeneID:6762246"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            125535..127538
                     /locus_tag="Sez_0113"
                     /db_xref="GeneID:6760622"
     CDS             125535..127538
                     /locus_tag="Sez_0113"
                     /note="similar to ref|YP_001450417.1|
                     bacteriocin-associated integral membrane protein subfamily
                     [Streptococcus gordonii str. Challis substr. CH1];
                     Unknown, bacteriocin associated membrane protein; putative
                     immunity protein."
                     /codon_start=1
                     /transl_table=11
                     /product="probable immunity protein"
                     /protein_id="YP_002122508.1"
                     /db_xref="GI:195977264"
                     /db_xref="GeneID:6760622"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLAKETDSLIAMQHQEPGPEGTPIVTYTLFGKGELPNGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTMLKPSFLGTVVLIFSSGSQALGLV
                     IFCLTFGALTLIGHIRALRTAGIRLISGERRWQIFLYPIRSDVCYCCLGLIFGFSLAA
                     VMGQFMSFSPLVLYLIGIGLVCYNLLLVFIALFFAGLFAIGIKKVHLMQVIKGQIPVR
                     GIISLILIGQLLAVLVVSFGASRTLLYVQAERQQERGQAVWRQEDKLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKAQAAHYQSVFEAAVT
                     GLASGEGHQPMTATVSCTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLRNAILLLYRQMRIENKMSLLILKGA"
     gene            127540..128208
                     /locus_tag="Sez_0114"
                     /db_xref="GeneID:6762242"
     CDS             127540..128208
                     /locus_tag="Sez_0114"
                     /note="similar to ref|ZP_01835894.1| ABC transporter,
                     ATP-binding protein [Streptococcus pneumoniae SP23-BS72];
                     Probably part of a binding-protein-dependent transport
                     system for an amino acid. Probably responsible for energy
                     coupling to the transport system; competence
                     damage-inducible protein A."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_002122509.1"
                     /db_xref="GI:195977265"
                     /db_xref="GeneID:6762242"
                     /translation="MIRLEKVSKGFGDRVLFSNLSMTFESGKVYALIGSSGSGKTTLM
                     NMMAALEDYQGEIFFRGKNLKTYKSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKLSKEEGQQRELEVLKAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHENRTIIIATHNPSIWEMADEVLSVDQLSLPKLQIKH
                     GLAK"
     gene            128366..129304
                     /gene="comGA"
                     /locus_tag="Sez_0115"
                     /db_xref="GeneID:6760621"
     CDS             128366..129304
                     /gene="comGA"
                     /locus_tag="Sez_0115"
                     /note="similar to ref|YP_595819.1| ComG operon protein 1
                     [Streptococcus pyogenes MGAS9429]; Required for uptake of
                     DNA by competent cells."
                     /codon_start=1
                     /transl_table=11
                     /product="late competence protein ComGA"
                     /protein_id="YP_002122510.1"
                     /db_xref="GI:195977266"
                     /db_xref="GeneID:6760621"
                     /translation="MVQELAKRLIRQAEELQAQDIYILPRGAGYELLMRIGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDGTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQASQWNQKIDQLLAEGHLNTKQARLEKIIQ"
     gene            129180..130271
                     /gene="comGB"
                     /locus_tag="Sez_0116"
                     /db_xref="GeneID:6762248"
     CDS             129180..130271
                     /gene="comGB"
                     /locus_tag="Sez_0116"
                     /note="similar to ref|YP_281451.1| comG operon protein 2
                     [Streptococcus pyogenes MGAS5005]; Required for
                     transformation and DNA binding."
                     /codon_start=1
                     /transl_table=11
                     /product="late competence protein ComGB"
                     /protein_id="YP_002122511.1"
                     /db_xref="GI:195977267"
                     /db_xref="GeneID:6762248"
                     /translation="MIVRKRNLNIIKPASGIRRLISFLQRDISIPSRQGLKKLSSKQQ
                     EKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYVTSMEASLLKGNGLADMLAALGYS
                     DAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKRKTIEAVTYPIILLGFLVVIMLGL
                     RHYLIPQLESQNALTDLLLHLPHYFLGFCLLLLSLIGSFYLYARSCSRLRLFSQLSYY
                     PIIGSLLRQYLTAYYAREWGNLIGQGLELITILEMMSNEKSQLMRELAKDIKQSLLAG
                     QSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELDIYSQESWETFFSQLNRATQWIQP
                     IIFLVVAVVIVMIYAAILLPIYQHMGDVF"
     gene            130272..130595
                     /gene="comGC"
                     /locus_tag="Sez_0117"
                     /db_xref="GeneID:6760620"
     CDS             130272..130595
                     /gene="comGC"
                     /locus_tag="Sez_0117"
                     /note="similar to ref|YP_601589.1| ComG operon protein 3
                     [Streptococcus pyogenes MGAS10750]; Involved in
                     competence."
                     /codon_start=1
                     /transl_table=11
                     /product="late competence protein ComGC"
                     /protein_id="YP_002122512.1"
                     /db_xref="GI:195977268"
                     /db_xref="GeneID:6760620"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            130573..130998
                     /gene="comGD"
                     /locus_tag="Sez_0118"
                     /db_xref="GeneID:6760909"
     CDS             130573..130998
                     /gene="comGD"
                     /locus_tag="Sez_0118"
                     /note="similar to ref|NP_663885.1| putative competence
                     protein [Streptococcus pyogenes MGAS315]; Involved in
                     competence."
                     /codon_start=1
                     /transl_table=11
                     /product="late competence protein ComGD"
                     /protein_id="YP_002122513.1"
                     /db_xref="GI:195977269"
                     /db_xref="GeneID:6760909"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLCLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            131158..131667
                     /gene="comGF"
                     /locus_tag="Sez_0119"
                     /db_xref="GeneID:6760619"
     CDS             131158..131667
                     /gene="comGF"
                     /locus_tag="Sez_0119"
                     /note="similar to ref|YP_281455.1| comG operon protein 6
                     [Streptococcus pyogenes MGAS5005]; Involved in
                     competence."
                     /codon_start=1
                     /transl_table=11
                     /product="ComG operon protein 6"
                     /protein_id="YP_002122514.1"
                     /db_xref="GI:195977270"
                     /db_xref="GeneID:6760619"
                     /translation="MVVILSYYHIRRVSLLLKKTKRLLGLKDSRLKAFTLIECLIALL
                     VISGSLLVYQALTKSLMVSERYLAANDQDNWLLFSQQLRAELSGTTLQGVSNNRLYVE
                     KDKKTLSFGQVKSHDFRKAAGNGRGYQPMLFSLSSSQITAVGQQVIIKLKWQSGLERT
                     FIYAFQEKG"
     gene            131645..132007
                     /gene="comGF"
                     /locus_tag="Sez_0120"
                     /db_xref="GeneID:6762292"
     CDS             131645..132007
                     /gene="comGF"
                     /locus_tag="Sez_0120"
                     /note="similar to ref|YP_059458.1| ComG operon protein 6
                     [Streptococcus pyogenes MGAS10394]; Involved in
                     competence."
                     /codon_start=1
                     /transl_table=11
                     /product="late competence protein ComGG"
                     /protein_id="YP_002122515.1"
                     /db_xref="GI:195977271"
                     /db_xref="GeneID:6762292"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLMAEMVYQEQPPSDGQIAFNCGQASYKSHKQRFIIEIKLPHQQLYQFSYPKV
                     QQVSQTSKKEPELKQSLP"
     gene            complement(132053..132856)
                     /locus_tag="Sez_0121"
                     /note="IS861B"
                     /db_xref="GeneID:6760618"
     CDS             complement(132053..132856)
                     /locus_tag="Sez_0121"
                     /note="similar to ref|NP_268574.1| putative transposase,
                     IS861 [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS861 orfB"
                     /protein_id="YP_002122516.1"
                     /db_xref="GI:195977272"
                     /db_xref="GeneID:6760618"
                     /translation="MLEILDLSRSTYYYQVKQLAQEDKDMDLKELIQGIYDEHHGNYG
                     YRRIHLELRNRGFIVNHKKVQRLMTVMGLKARIRRKRKYSSYKGEVGKKADNLIKRQF
                     EGSKPYEKCYTDVTEFTLPEGKLYLSPVLDGYNSEIIDFTLSRSPDLKQVQTMLEKAF
                     PADSYNGTILHSDQGWQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFFGILKSE
                     MFYGLETTYQSLNELEQAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
     gene            complement(132880..133395)
                     /locus_tag="Sez_0122"
                     /note="IS861A"
                     /db_xref="GeneID:6762096"
     CDS             complement(132880..133395)
                     /locus_tag="Sez_0122"
                     /note="similar to ref|YP_602677.1| Transposase
                     [Streptococcus pyogenes MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS861 orfA"
                     /protein_id="YP_002122517.1"
                     /db_xref="GI:195977273"
                     /db_xref="GeneID:6762096"
                     /translation="MTLSYEDKVQIYELRHIGKSIKCLSEKFSIAESDLKYMIRLIDR
                     YGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTSLDYALPNSSMLSRWIAQYKKN
                     GYTILEKRRGRPPKMGRQPKKTLEQMTELERLQKELDYLRAENAVLKKLREYRLRDEA
                     KLKEQQKSSKN"
     gene            133501..134454
                     /locus_tag="Sez_0123"
                     /db_xref="GeneID:6760617"
     CDS             133501..134454
                     /locus_tag="Sez_0123"
                     /note="similar to ref|YP_595826.1| adenine-specific
                     methyltransferase [Streptococcus pyogenes MGAS9429];
                     Unknown, COG0827 Adenine-specific DNA methylase."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific methyltransferase"
                     /protein_id="YP_002122518.1"
                     /db_xref="GI:195977274"
                     /db_xref="GeneID:6760617"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAVRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            134514..135716
                     /gene="ackA"
                     /locus_tag="Sez_0124"
                     /db_xref="GeneID:6762257"
     CDS             134514..135716
                     /gene="ackA"
                     /locus_tag="Sez_0124"
                     /note="similar to ref|YP_001127687.1| acetate kinase
                     [Streptococcus pyogenes str. Manfredo]; Involved in the
                     activation of acetate to acetyl coA and the secretion of
                     acetate. During anaerobic growth of the organism, this
                     enzyme is also involved in the synthesis of most of the
                     ATP formed catabolically."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase AckA"
                     /protein_id="YP_002122519.1"
                     /db_xref="GI:195977275"
                     /db_xref="GeneID:6762257"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIDTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKKTVSS"
     gene            complement(136088..136702)
                     /locus_tag="Sez_0125"
                     /db_xref="GeneID:6760616"
     CDS             complement(136088..136702)
                     /locus_tag="Sez_0125"
                     /note="similar to ref|ZP_01817412.1| hypothetical protein
                     CGSSp3BS71_02812 [Streptococcus pneumoniae SP3-BS71]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122520.1"
                     /db_xref="GI:195977276"
                     /db_xref="GeneID:6760616"
                     /translation="MKKVKQLIIAMIASLLLIVNTVPSIVYASEVTRISQKHQAVNEA
                     INEIDIILDNPIYVSENELNSRIQEAKVRYPNLSEERMKVLAYQTLSPYSFRASVWDG
                     QGVTLDEFAWVVENLIAATISGGIGGIGNLVKQKGLAAAKATLSRVAKNAAMRIGVYS
                     AWLAGTLERVFDYINIFYNVGYAVAQWVDARDFHPNNGRINAWA"
     gene            137231..139273
                     /locus_tag="Sez_0126"
                     /db_xref="GeneID:6760914"
     CDS             137231..139273
                     /locus_tag="Sez_0126"
                     /note="similar to ref|ZP_00784694.1| transcriptional
                     antiterminator, BglG family [Streptococcus agalactiae
                     COH1]; Transcriptional antiterminator."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, BglG family"
                     /protein_id="YP_002122521.1"
                     /db_xref="GI:195977277"
                     /db_xref="GeneID:6760914"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELND
                     FLAQHELSELQATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELRYTRASGYTLVGDELDKHRLA
                     LAMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQACLY
                     AFIFILCRYQRRVDRVKQRPVVVSEQLDQLTALLVSEIMQQLSLRYQLFEADEAYFQL
                     LLAGCFEGEGTVSDDFFESLTAAIVDQMQGVALLSFSQSDQLKEDLKRHLIPAYYRLR
                     YGLPSDNDYTLRVKDSYSELFDLVKQSLEPLAKELDSPIPDSEIAYFVLHFGGYLKQQ
                     GKDFHRQAYRAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDESCYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQDVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGPFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            139275..139562
                     /locus_tag="Sez_0127"
                     /db_xref="GeneID:6760615"
     CDS             139275..139562
                     /locus_tag="Sez_0127"
                     /note="similar to ref|NP_687232.1| PTS system, IIB
                     component, putative [Streptococcus agalactiae 2603V/R];
                     Probably involved in ascorbate uptake."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphotransferase component II B"
                     /protein_id="YP_002122522.1"
                     /db_xref="GI:195977278"
                     /db_xref="GeneID:6760615"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAGHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            139575..140918
                     /gene="sgaT"
                     /locus_tag="Sez_0128"
                     /db_xref="GeneID:6760917"
     CDS             139575..140918
                     /gene="sgaT"
                     /locus_tag="Sez_0128"
                     /note="similar to ref|NP_359529.1| ascorbate-specific PTS
                     system enzyme IIC [Streptococcus pneumoniae R6]; Could act
                     as the transport protein for the unknown pentitol
                     substrate of the sga operon."
                     /codon_start=1
                     /transl_table=11
                     /product="putative PTS system enzyme IIC SgaT"
                     /protein_id="YP_002122523.1"
                     /db_xref="GI:195977279"
                     /db_xref="GeneID:6760917"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFMILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIVYPYAPNAVLIGFVSSFVGGLVSMAVMIAS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVVLAILVGLSVVGKSAAKEE"
     gene            140921..142707
                     /gene="tkt"
                     /locus_tag="Sez_0129"
                     /note="putative transketolase"
                     /db_xref="GeneID:6760613"
     gene            142912..143034
                     /locus_tag="Sez_0131"
                     /db_xref="GeneID:6760913"
     CDS             142912..143034
                     /locus_tag="Sez_0131"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122524.1"
                     /db_xref="GI:195977280"
                     /db_xref="GeneID:6760913"
                     /translation="MRFYLQLFWSGLIGLFVIATKLLAIVRAVFMKLEKNRLIS"
     gene            143257..145152
                     /gene="pepO"
                     /locus_tag="Sez_0132"
                     /db_xref="GeneID:6760612"
     CDS             143257..145152
                     /gene="pepO"
                     /locus_tag="Sez_0132"
                     /note="similar to ref|YP_597524.1| oligoendopeptidase O
                     [Streptococcus pyogenes MGAS9429]; Unknown, COG3590
                     Predicted metalloendopeptidase."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase PepO"
                     /protein_id="YP_002122525.1"
                     /db_xref="GI:195977281"
                     /db_xref="GeneID:6760612"
                     /translation="MTTYQEDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEAKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDDIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHTYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(145352..146407)
                     /gene="tsf"
                     /locus_tag="Sez_0133"
                     /db_xref="GeneID:6760912"
     CDS             complement(145352..146407)
                     /gene="tsf"
                     /locus_tag="Sez_0133"
                     /note="similar to gb|AAX72875.1| protein translation
                     elongation factor Ts (EF-Ts) [Streptococcus pyogenes
                     MGAS6180]; Associates with the EF-Tu.GDP complex and
                     induces the exchange of GDP to GTP. It remains bound to
                     the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP
                     hydrolysis stage on the ribosome."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="YP_002122526.1"
                     /db_xref="GI:195977282"
                     /db_xref="GeneID:6760912"
                     /translation="MEEIKMAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIE
                     LLREKGMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATA
                     KAIAEGKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGA
                     YQHNGGRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAI
                     ELDNESRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPG
                     KMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKA
                     NDFESEVAATMAAALNN"
     gene            complement(146560..147315)
                     /gene="rpsB"
                     /locus_tag="Sez_0134"
                     /db_xref="GeneID:6760611"
     CDS             complement(146560..147315)
                     /gene="rpsB"
                     /locus_tag="Sez_0134"
                     /note="similar to ref|NP_270023.1| 30S ribosomal protein
                     S2 [Streptococcus pyogenes M1 GAS]; Unknown, ribosome
                     structural component."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="YP_002122527.1"
                     /db_xref="GI:195977283"
                     /db_xref="GeneID:6760611"
                     /translation="MKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKL
                     ADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLTNWGTI
                     QKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVD
                     PHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLADAVIE
                     GRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            complement(147791..149322)
                     /gene="ahpF"
                     /locus_tag="Sez_0135"
                     /note="alkyl hydroperoxide reductase protein F;
                     unconfirmed disrupted gene, a potential error in the
                     sequence asssembly"
                     /db_xref="GeneID:6762267"
     gene            complement(149343..149903)
                     /gene="ahpC"
                     /locus_tag="Sez_0137"
                     /db_xref="GeneID:6760610"
     CDS             complement(149343..149903)
                     /gene="ahpC"
                     /locus_tag="Sez_0137"
                     /note="similar to ref|NP_270011.1| putative alkyl
                     hydroperoxidase [Streptococcus pyogenes M1 GAS]; Directly
                     reduces organic hydroperoxides in its reduced dithiol
                     form."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="YP_002122528.1"
                     /db_xref="GI:195977284"
                     /db_xref="GeneID:6760610"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            150252..150325
                     /locus_tag="Sez_1999"
                     /note="tRNA_32"
                     /db_xref="GeneID:6762269"
     tRNA            150252..150325
                     /locus_tag="Sez_1999"
                     /product="tRNA-Cys"
                     /note="anticodon GCA"
                     /db_xref="GeneID:6762269"
     gene            150535..150738
                     /gene="cspA"
                     /locus_tag="Sez_0138"
                     /db_xref="GeneID:6760859"
     CDS             150535..150738
                     /gene="cspA"
                     /locus_tag="Sez_0138"
                     /note="similar to ref|NP_270010.1| putative cold shock
                     protein [Streptococcus pyogenes M1 GAS]; Stimulates the
                     transcription of cold-shock-inducible promoters."
                     /codon_start=1
                     /transl_table=11
                     /product="major cold-shock protein"
                     /protein_id="YP_002122529.1"
                     /db_xref="GI:195977285"
                     /db_xref="GeneID:6760859"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            150910..151371
                     /gene="ctsR"
                     /locus_tag="Sez_0139"
                     /db_xref="GeneID:6760609"
     CDS             150910..151371
                     /gene="ctsR"
                     /locus_tag="Sez_0139"
                     /note="similar to ref|YP_599441.1| Transcriptional
                     regulator ctsR [Streptococcus pyogenes MGAS10270];
                     Negative regulator of class III stress genes (clpC,
                     clpP)."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CtsR"
                     /protein_id="YP_002122530.1"
                     /db_xref="GI:195977286"
                     /db_xref="GeneID:6760609"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDRLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAIASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            151392..153812
                     /gene="clpC"
                     /locus_tag="Sez_0140"
                     /db_xref="GeneID:6760924"
     CDS             151392..153812
                     /gene="clpC"
                     /locus_tag="Sez_0140"
                     /note="similar to ref|YP_603351.1| Negative regulator of
                     genetic competence clpC/mecB [Streptococcus pyogenes
                     MGAS10750]; Part of a stress-induced multi-chaperone
                     system, it is involved in the recovery of the cell from
                     heat-induced damage, in cooperation with dnaK, dnaJ and
                     grpE. Acts before dnaK, in the processing of protein
                     aggregates. Protein binding stimulates the ATPase
                     activity; ATP hydrolysis unfolds the denatured protein
                     aggregates, which probably helps expose new hydrophobic
                     binding sites on the surface of clpB-bound aggregates,
                     contributing to the solubilization and refolding of
                     denatured protein aggregates by dnaK."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="YP_002122531.1"
                     /db_xref="GI:195977287"
                     /db_xref="GeneID:6760924"
                     /translation="MQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEF
                     ERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVTNEHEVGSE
                     HVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKETIKAIHE
                     LRKPKKTKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQV
                     LCRKTKNNPVLVGDAGVGKTALAYGLAQRIASGVIPYELQDMRVLELDMMSVVAGTRF
                     RGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPALSRGTLH
                     MVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVDDAYQILLGLRASYEQYHNVTISD
                     KAVHTAVKLAQRYLTSKRLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDM
                     SKVSALLAKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLNLEKELHK
                     RVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALAELLFDDE
                     SALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHP
                     DIFNILLQVLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDH
                     QAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAALAEKHIS
                     LKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLKIGVSH
                     GKLAFDIA"
     gene            154581..155012
                     /locus_tag="Sez_0141"
                     /db_xref="GeneID:6760608"
     CDS             154581..155012
                     /locus_tag="Sez_0141"
                     /note="similar to ref|NP_688051.1| hypothetical protein
                     SAG1041 [Streptococcus agalactiae 2603V/R]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122532.1"
                     /db_xref="GI:195977288"
                     /db_xref="GeneID:6760608"
                     /translation="MKKSTKAFISLMILIGGLLMVFSLNGKRTEEQQKRDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGGSYHPD
                     TFKLVEKNSLEEMGPVRYRIKDIEKVSLEGVAVTYSHEERS"
     gene            155044..156303
                     /locus_tag="Sez_0142"
                     /db_xref="GeneID:6760920"
     CDS             155044..156303
                     /locus_tag="Sez_0142"
                     /note="similar to ref|ZP_00874485.1| Lipase, class 3
                     [Streptococcus suis 89/1591]; Unknown, has lipase class 3
                     domain."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122533.1"
                     /db_xref="GI:195977289"
                     /db_xref="GeneID:6760920"
                     /translation="MAKQVYNIEPSKAKSNDAPIVLKGNRLIDYNTGKQYRVLLVQDN
                     NNDAHKTNDNGMQAMAVAPIVKGDVDTSQVVIAYSGTNAADSRDLDTDWQLLIRGNQD
                     DLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAYLALIVAAEHK
                     IPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFGTDDLAISRNV
                     DAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLNVLASKKSMSSYH
                     KLKKHWQSTGKGISGSEELFLDAAQGMILGSSMAKAAREGADEALDHKTVADAKLMEV
                     WSAIDFNAFHELLYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSALATDFENLNR
                     DIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            156309..156677
                     /locus_tag="Sez_0143"
                     /db_xref="GeneID:6760607"
     CDS             156309..156677
                     /locus_tag="Sez_0143"
                     /note="similar to ref|ZP_00874484.1| hypothetical protein
                     SsuiDRAFT_1541 [Streptococcus suis 89/1591]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122534.1"
                     /db_xref="GI:195977290"
                     /db_xref="GeneID:6760607"
                     /translation="MAIYRKLREMDDAEQDFLRQKKAYQKREDSLSERRHVLDDLINS
                     EYQKVGAFLKRLDLSVNAASDFFNELGRLKDQSNAEFHLQRAALEEERAQSTKTFRQE
                     QAQREAELLDMRRAYANTNN"
     gene            156658..156948
                     /locus_tag="Sez_0144"
                     /db_xref="GeneID:6762302"
     CDS             156658..156948
                     /locus_tag="Sez_0144"
                     /note="similar to ref|ZP_00874545.1| hypothetical protein
                     SsuiDRAFT_1602 [Streptococcus suis 89/1591]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122535.1"
                     /db_xref="GI:195977291"
                     /db_xref="GeneID:6762302"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            157248..157535
                     /gene="groS"
                     /locus_tag="Sez_0145"
                     /db_xref="GeneID:6760606"
     CDS             157248..157535
                     /gene="groS"
                     /locus_tag="Sez_0145"
                     /note="similar to gb|AAR29453.1| GroES [Streptococcus
                     bovis]; Assisting in the covalent and noncovalent assembly
                     of single chain polypeptides or multisubunit complexes
                     into the correct tertiary structure."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein 60 family co-chaperone GroES"
                     /protein_id="YP_002122536.1"
                     /db_xref="GI:195977292"
                     /db_xref="GeneID:6760606"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
     gene            157603..159228
                     /gene="groL"
                     /locus_tag="Sez_0146"
                     /db_xref="GeneID:6760931"
     CDS             157603..159228
                     /gene="groL"
                     /locus_tag="Sez_0146"
                     /note="similar to ref|NP_608082.1| chaperonin GroEL
                     [Streptococcus pyogenes MGAS8232]; Prevents misfolding and
                     promotes the refolding and proper assembly of unfolded
                     polypeptides generated under stress conditions."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein 60 family chaperone GroEL"
                     /protein_id="YP_002122537.1"
                     /db_xref="GI:195977293"
                     /db_xref="GeneID:6760931"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGVGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(159562..160032)
                     /locus_tag="Sez_0147"
                     /db_xref="GeneID:6760605"
     CDS             complement(159562..160032)
                     /locus_tag="Sez_0147"
                     /note="similar to ref|YP_001450297.1| Phosphohydrolase
                     (MutT/nudix family protein) [Streptococcus gordonii str.
                     Challis substr. CH1]"
                     /codon_start=1
                     /transl_table=11
                     /product="MutT/nudix family protein"
                     /protein_id="YP_002122538.1"
                     /db_xref="GI:195977294"
                     /db_xref="GeneID:6760605"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEAFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            160339..160665
                     /locus_tag="Sez_0148"
                     /db_xref="GeneID:6760934"
     CDS             160339..160665
                     /locus_tag="Sez_0148"
                     /note="similar to ref|ZP_01824093.1| hypothetical protein
                     CGSSp9BS68_00132 [Streptococcus pneumoniae SP9-BS68]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122539.1"
                     /db_xref="GI:195977295"
                     /db_xref="GeneID:6760934"
                     /translation="MRANGLSRRKRMAILERHHKILLLSMALGAASWLALGFMSLPNL
                     AGALGISTSSASTTVNLLSAYSTVSSVIAIVGAITGVGSIGAGIAATVYTLSNTKERL
                     LLFSGS"
     gene            160675..161814
                     /locus_tag="Sez_0149"
                     /db_xref="GeneID:6760604"
     CDS             160675..161814
                     /locus_tag="Sez_0149"
                     /note="similar to ref|ZP_01824094.1| hypothetical protein
                     CGSSp9BS68_00137 [Streptococcus pneumoniae SP9-BS68]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122540.1"
                     /db_xref="GI:195977296"
                     /db_xref="GeneID:6760604"
                     /translation="MKHVFKYHNGNILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVS
                     TGIICLAIAFPEQLVWIALSVLAVFIYWLSLSLATIFQVAGRILNLLMIYGMYLHQES
                     LVIACICLNAVILVLNITIDFRYPYQWLAVRAEKTENTITLLRLVVNMITDHLALMIL
                     FIIFCIATTYFTQRLLLLFDYSSFSIPVFFLSATTYITLLEVMVGKDIKELELDRGLV
                     VLHFLNKDISVYKAYRNSQFLLSAHILAVIHAGCVIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSIKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            162290..162877
                     /locus_tag="Sez_0150"
                     /db_xref="GeneID:6762322"
     CDS             162290..162877
                     /locus_tag="Sez_0150"
                     /note="similar to ref|ZP_01824096.1| ATPase [Streptococcus
                     pneumoniae SP9-BS68]; Part ABC transporter complex."
                     /codon_start=1
                     /transl_table=11
                     /product="Nod factor export ATP-binding protein I
                     (Nodulation ATP-binding protein I)"
                     /protein_id="YP_002122541.1"
                     /db_xref="GI:195977297"
                     /db_xref="GeneID:6762322"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVID
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALLTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHKQLLSESRVIYLNGKGEIY"
     gene            162874..163356
                     /locus_tag="Sez_0151"
                     /db_xref="GeneID:6760603"
     CDS             162874..163356
                     /locus_tag="Sez_0151"
                     /note="similar to ref|ZP_01819232.1| hypothetical protein
                     CGSSp6BS73_09666 [Streptococcus pneumoniae SP6-BS73]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122542.1"
                     /db_xref="GI:195977298"
                     /db_xref="GeneID:6760603"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEALL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLVALLLKLPPSPLFQFVVNALGIVIMYGLSIKRQGNKATALLFCLPFTLDILVALLI"
     gene            163381..163896
                     /locus_tag="Sez_0152"
                     /db_xref="GeneID:6762327"
     CDS             163381..163896
                     /locus_tag="Sez_0152"
                     /note="similar to ref|ZP_01819367.1|
                     succinyl-diaminopimelate desuccinylase [Streptococcus
                     pneumoniae SP6-BS73]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122543.1"
                     /db_xref="GI:195977299"
                     /db_xref="GeneID:6762327"
                     /translation="MKKTLYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLARLYSDDMLRATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSN
                     VELTSSVGIDV"
     gene            164530..166164
                     /locus_tag="Sez_0153"
                     /db_xref="GeneID:6760602"
     CDS             164530..166164
                     /locus_tag="Sez_0153"
                     /note="similar to ref|NP_608080.1| hypothetical protein
                     spyM18_2125 [Streptococcus pyogenes MGAS8232]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122544.1"
                     /db_xref="GI:195977300"
                     /db_xref="GeneID:6760602"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRHQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDHKIKVSKTYDGKNHTLDLRVTFKTFTVTSNVRDGELYVDGERV
                     ETLKAGQLQLEEYPVTETAKSYIKKTFPDGELTSSKHALAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAAYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(166305..167198)
                     /gene="yhcT"
                     /locus_tag="Sez_0154"
                     /db_xref="GeneID:6760932"
     CDS             complement(166305..167198)
                     /gene="yhcT"
                     /locus_tag="Sez_0154"
                     /note="similar to ref|NP_722253.1| putative
                     pseudouridylate synthase [Streptococcus mutans UA159];
                     Responsible For Synthesis Of Pseudouridine From Uracil At
                     Positions 955, 2504 And 2580 In 23s Ribosomal RNA."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     D"
                     /protein_id="YP_002122545.1"
                     /db_xref="GI:195977301"
                     /db_xref="GeneID:6760932"
                     /translation="MTIANKPEMGFQVSLTNPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPALVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LERRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLT
                     QEMIRVTAPSKSFEEGLQQLN"
     gene            complement(167182..167379)
                     /locus_tag="Sez_0155"
                     /db_xref="GeneID:6760601"
     CDS             complement(167182..167379)
                     /locus_tag="Sez_0155"
                     /note="similar to ref|NP_665564.1| hypothetical protein
                     SpyM3_1760 [Streptococcus pyogenes MGAS315]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122546.1"
                     /db_xref="GI:195977302"
                     /db_xref="GeneID:6760601"
                     /translation="MIMNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVAL
                     ATQMAINLIEKYHDWLNDNSK"
     gene            167608..169350
                     /locus_tag="Sez_0156"
                     /db_xref="GeneID:6760928"
     CDS             167608..169350
                     /locus_tag="Sez_0156"
                     /note="similar to ref|NP_688485.1| hypothetical protein
                     SAG1491 [Streptococcus agalactiae 2603V/R]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="YP_002122547.1"
                     /db_xref="GI:195977303"
                     /db_xref="GeneID:6760928"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQDRTYNDTHYYN
                     YYDNTRDTADNGIADWGRVTRYRYYRETYYQLEAERQQLVRTYLELKAAYDNQIALNS
                     QQLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNLQSYQTLLQQLSLADFVSQ
                     HKDRLDALTRLDTERARLIDAWWESDSNYSDLNTNLTLVNGYIKELNQALQELLKDHQ
                     GKMTSDLRTLEDRQAELARWLTDIESRPKRQATSHARGSQTHWRSASRADVALWNELR
                     NEGDHAFAMTDNALPSQPYRADLTAVHDLEALQAQSDKAHRLRAKEIVFTLQRSNISR
                     QGDIDLSGAITAFVKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMTDDQY
                     KEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQTPYA
                     FIKDKEAVCQAYAQLFKDMGQLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQYYHI
                     DLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRTFPRYGTYAA
                     NDSRNTFYPRYSYA"
     gene            169491..169871
                     /locus_tag="Sez_0157"
                     /db_xref="GeneID:6760600"
     CDS             169491..169871
                     /locus_tag="Sez_0157"
                     /note="similar to ref|ZP_00365970.1| COG0251: Putative
                     translation initiation inhibitor, yjgF family
                     [Streptococcus pyogenes M49 591]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation inhibitor"
                     /protein_id="YP_002122548.1"
                     /db_xref="GI:195977304"
                     /db_xref="GeneID:6760600"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEAVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKSLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            169909..172230
                     /locus_tag="Sez_0158"
                     /db_xref="GeneID:6760938"
     CDS             169909..172230
                     /locus_tag="Sez_0158"
                     /note="similar to ref|YP_061071.1| Multimodular
                     transpeptidase-transglycosylase PBP 2A [Streptococcus
                     pyogenes MGAS10394]; Cell wall formation. May be involved
                     in outgrowth of the germinated spore or it could function
                     in the synthesis of the germ cell wall."
                     /codon_start=1
                     /transl_table=11
                     /product="multimodular transpeptidase-transglycosylase"
                     /protein_id="YP_002122549.1"
                     /db_xref="GI:195977305"
                     /db_xref="GeneID:6760938"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEAAVAALADQE
                     AQAGQTRGQSVLQRSKSYGAKRKKQPVWLQRLEAILPSSQNPIRRFLRRYHIGKILLI
                     LMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYVELDA
                     ISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYLSQEQ
                     SIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAANLTL
                     DEAATLAGMLKGPEIYNPYYSIENATNRRDTVLSAMVDAGKISKQQAQEAQAIGMGNR
                     LADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAGMQTT
                     FNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQAKRS
                     PASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETVPMYQALANSY
                     NIPAVSILDQLGVDKAFSYGEKFGLKMSDTKKELGVALGSGVTTNPLEMAQAYAVFAN
                     GGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAVNANV
                     YGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSSAGTA
                     SAIFSTQASYILPYTKGSQFKIDNAYAQNGISAVYGINETNTQAGIDSQSIIDSLRKS
                     AEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            172443..172619
                     /gene="secE"
                     /locus_tag="Sez_0159"
                     /db_xref="GeneID:6760598"
     CDS             172443..172619
                     /gene="secE"
                     /locus_tag="Sez_0159"
                     /note="similar to dbj|BAD77787.1| SecE [Streptococcus
                     dysgalactiae subsp. equisimilis]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="YP_002122550.1"
                     /db_xref="GI:195977306"
                     /db_xref="GeneID:6760598"
                     /translation="MGFISGIFKLLRDTAWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            173010..173555
                     /gene="nusG"
                     /locus_tag="Sez_0160"
                     /db_xref="GeneID:6762279"
     CDS             173010..173555
                     /gene="nusG"
                     /locus_tag="Sez_0160"
                     /note="similar to ref|NP_268543.1| transcription
                     antitermination protein NusG [Streptococcus pyogenes M1
                     GAS]; Influences transcription termination and
                     antitermination. Acts as a component of the transcription
                     complex, and interacts with the termination factor rho and
                     RNA polymerase."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination protein NusG"
                     /protein_id="YP_002122551.1"
                     /db_xref="GI:195977307"
                     /db_xref="GeneID:6762279"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDVVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            complement(173544..173666)
                     /locus_tag="Sez_0161"
                     /db_xref="GeneID:6760599"
     CDS             complement(173544..173666)
                     /locus_tag="Sez_0161"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122552.1"
                     /db_xref="GI:195977308"
                     /db_xref="GeneID:6760599"
                     /translation="MSLGRRRPTKKDLTSVSEKADASLLFLYGMNNRFKSLSGR"
     gene            174028..175035
                     /gene="sclZ.3"
                     /locus_tag="Sez_0162"
                     /db_xref="GeneID:6762288"
     CDS             174028..175035
                     /gene="sclZ.3"
                     /locus_tag="Sez_0162"
                     /note="similar to gb|ABA41496.1| collagen-like protein F
                     [Streptococcus equi subsp. equi]; Possible adhesin, has a
                     collagen-structural-motif domain composed of 55
                     Gly-Xaa-Yaa repeats."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein SclZ.3"
                     /protein_id="YP_002122553.1"
                     /db_xref="GI:195977309"
                     /db_xref="GeneID:6762288"
                     /translation="MARKHLNKYARRYGLTSAAIVLMAAAIGSGTSVQAQERDLKVLI
                     DKISKYSSVDEFVQRNHSIVGNHYTTISIKNYLHMLERYFKDYFNVLNEELKIPGPTG
                     PRGEPGPVGPAGPRGERGPQGLPGDKGETGERGETGPAGPIGPQGPKGDQGEMGPQGP
                     KGDQGEMGPQGPKGDQGEIGPQGPKGDQGEMGPQGPKGDQGEIGPQGPKGDQGEVGPQ
                     GPKGDQGEVGPQGPKGDQGEMGPQGPKGDQGEVGPQGPDSSQGEQGQESKPDMPAPKA
                     PEQIPAPQAPSTATKMVSRPQKAAALPATGETSNPFFSLAALSIIASAGMLTLKEKKD
                     R"
     gene            175795..177312
                     /gene="mgaZ"
                     /locus_tag="Sez_0163"
                     /db_xref="GeneID:6760597"
     CDS             175795..177312
                     /gene="mgaZ"
                     /locus_tag="Sez_0163"
                     /note="similar to emb|CAB65412.1| putative Mga-like
                     regulatory protein [Streptococcus dysgalactiae subsp.
                     dysgalactiae]; Probable positive regulator of the adjacent
                     M-like protein."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="YP_002122554.1"
                     /db_xref="GI:195977310"
                     /db_xref="GeneID:6760597"
                     /translation="MSIDNLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLTEVKIDFAIFRHLKLLSAVNLIRYLKGF
                     KIGKHKALNSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLGK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDINE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            177487..178665
                     /gene="spaZ"
                     /locus_tag="Sez_0164"
                     /db_xref="GeneID:6760937"
     CDS             177487..178665
                     /gene="spaZ"
                     /locus_tag="Sez_0164"
                     /note="similar to gb|AAB71984.1| M-protein [Streptococcus
                     equi]; Binds IgG molecules of the Ig1, Ig2 and Ig4
                     subclasses, and also binds fibrinogen."
                     /codon_start=1
                     /transl_table=11
                     /product="protective antigen-like protein, fibrinogen- and
                     Ig-binding protein precursor"
                     /protein_id="YP_002122555.1"
                     /db_xref="GI:195977311"
                     /db_xref="GeneID:6760937"
                     /translation="MKSCKSTLRKAAMAAMLAGAITTTGGVKAEENFDFYNHVMQFLE
                     DKSDDESYEKLGKAFEKLPEEQMKALFRIWFSADNSDGISQSVMSIAHKLKEKEQLEF
                     KEVGEMLWNSVTDELDRRIDSEASLKKDKVELQDNLNKAIKVSTDLMNQLGAAKADRD
                     KAQAEADRLSQAVDSLGRLTNSAKRELTEKLAEIDQLTQDKAKAASDLETANANITTL
                     QEELAGAKASYDKLSEDKAAADQALAEANVRVSELEQQVAAANNRVVDLEAQLAEKTA
                     ELDMVKADKAELEAKVKELQSLLEQKDRSNADLQANIERLKQELADKFKDQAQPRAKT
                     PQASNLVAKQKASRPAAKPAGQLPSTGEDAANPFFTAAAVAIMTGASLVTVMPKRQKD"
     gene            complement(178713..178874)
                     /locus_tag="Sez_0165"
                     /db_xref="GeneID:6760596"
     CDS             complement(178713..178874)
                     /locus_tag="Sez_0165"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122556.1"
                     /db_xref="GI:195977312"
                     /db_xref="GeneID:6760596"
                     /translation="MTSLGFRSGLALVLSSQRGIELDQGVLAKLLKSPLSFLSDKRLN
                     RAYRNANVH"
     gene            179254..181755
                     /gene="leuS"
                     /locus_tag="Sez_0166"
                     /db_xref="GeneID:6760936"
     CDS             179254..181755
                     /gene="leuS"
                     /locus_tag="Sez_0166"
                     /note="similar to ref|NP_606474.1| leucyl-tRNA synthetase
                     [Streptococcus pyogenes MGAS8232]; Catalysis of ATP +
                     L-leucine + tRNA(Leu) = AMP + diphosphate +
                     L-leucyl-tRNA(Leu)."
                     /codon_start=1
                     /transl_table=11
                     /product="Leucyl-tRNA synthetase"
                     /protein_id="YP_002122557.1"
                     /db_xref="GI:195977313"
                     /db_xref="GeneID:6760936"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AAAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSGFLDGLDKACA
                     ITKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            181942..182286
                     /locus_tag="Sez_0167"
                     /db_xref="GeneID:6760595"
     CDS             181942..182286
                     /locus_tag="Sez_0167"
                     /note="similar to ref|NP_268734.1| hypothetical protein
                     SPy_0435 [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122558.1"
                     /db_xref="GI:195977314"
                     /db_xref="GeneID:6760595"
                     /translation="MKKLVLASAAALVLAGAVVGTGEVRANSYSADSRYLTQNGSSRR
                     DMLRATKQNAKLQISNIRDSYKGYTSSQEARFYLIEMMKKRSEEEVNKVVSQYEELCK
                     SRWEKDESFIAY"
     gene            182494..183927
                     /gene="sgaT"
                     /locus_tag="Sez_0168"
                     /db_xref="GeneID:6762285"
     CDS             182494..183927
                     /gene="sgaT"
                     /locus_tag="Sez_0168"
                     /note="similar to ref|YP_601648.1| ascorbate-specific PTS
                     system enzyme IIC [Streptococcus pyogenes MGAS10750];
                     Could act as the transport protein for the unknown
                     pentitol substrate of the sga operon."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system, 3-keto-L-gulonate/L-ascorbate
                     specific IIC component (SgaT)"
                     /protein_id="YP_002122559.1"
                     /db_xref="GI:195977315"
                     /db_xref="GeneID:6762285"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGSGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGL
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPSFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            184043..184321
                     /gene="sgaB"
                     /locus_tag="Sez_0169"
                     /db_xref="GeneID:6760594"
     CDS             184043..184321
                     /gene="sgaB"
                     /locus_tag="Sez_0169"
                     /note="similar to ref|NP_268554.1| hypothetical protein
                     SPy_0175 [Streptococcus pyogenes M1 GAS]; The
                     phosphoenolpyruvate-dependent sugar phosphotransferase
                     system (PTS), a major carbohydrate active -transport
                     system, catalyzes the phosphorylation of incoming sugar
                     substrates concomitant with their translocation across the
                     cell membrane. This system is involved in ascorbate
                     transport."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system, 3-keto-L-gulonate/L-ascorbate
                     specific IIB component (SgaB)"
                     /protein_id="YP_002122560.1"
                     /db_xref="GI:195977316"
                     /db_xref="GeneID:6760594"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            184538..185023
                     /gene="sgaC"
                     /locus_tag="Sez_0170"
                     /db_xref="GeneID:6760940"
     CDS             184538..185023
                     /gene="sgaC"
                     /locus_tag="Sez_0170"
                     /note="similar to ref|YP_601650.1| PTS system,
                     3-keto-L-gulonate specific IIA component [Streptococcus
                     pyogenes MGAS10750]; The phosphoenolpyruvate-dependent
                     sugar phosphotransferase system (PTS), a major
                     carbohydrate active -transport system, catalyzes the
                     phosphorylation of incoming sugar substrates concomitant
                     with their translocation across the cell membrane. This
                     system is involved in ascorbate transport."
                     /codon_start=1
                     /transl_table=11
                     /product="ascorbate-specific phosphotransferase enzyme IIA
                     component"
                     /protein_id="YP_002122561.1"
                     /db_xref="GI:195977317"
                     /db_xref="GeneID:6760940"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLSQPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLIACRTPEEVLALVDESKNSPYLEGLDLD
                     S"
     gene            185121..185783
                     /gene="sgaH"
                     /locus_tag="Sez_0171"
                     /db_xref="GeneID:6760593"
     CDS             185121..185783
                     /gene="sgaH"
                     /locus_tag="Sez_0171"
                     /note="similar to ref|NP_606478.1|
                     3-keto-L-gulonate-6-phosphate decarboxylase [Streptococcus
                     pyogenes MGAS8232]; Condensation of D-ribulose 5-phosphate
                     with formaldehyde to form D-arabino-6-hexulose
                     3-phosphate."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate 6-phosphate decarboxylase"
                     /protein_id="YP_002122562.1"
                     /db_xref="GI:195977318"
                     /db_xref="GeneID:6760593"
                     /translation="MTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALKA
                     IKEERGDRGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNKV
                     KALIDMGFRVSVTGGLDINTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRI
                     WG"
     gene            185683..186651
                     /gene="sgaU"
                     /locus_tag="Sez_0172"
                     /db_xref="GeneID:6760916"
     CDS             185683..186651
                     /gene="sgaU"
                     /locus_tag="Sez_0172"
                     /note="similar to ref|YP_001127742.1| putative L-xylulose
                     5-phosphate 3-epimerase [Streptococcus pyogenes str.
                     Manfredo]; Isomerization of D-arabino-6-hexulose
                     3-phosphate to D- fructose 6-phosphate."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulose 5-phosphate 3-epimerase"
                     /protein_id="YP_002122563.1"
                     /db_xref="GI:195977319"
                     /db_xref="GeneID:6760916"
                     /translation="MSLPLLQVVVSLKQRILQQRHVPLKTRFDAFGGNNMARPIGIYE
                     KATPKHFTWLERLQFAKALGFDFVEMSVDESDARLARLDWSKQERLDIVKAIYETGVR
                     IPSICFSGHRRYPLGSSNPETEATSLELMKKCIVLAQDLGVRTIQLAGYDVYYEEKSP
                     ETRARFIKNLRQACTWAEEAQVILAIEIMDDPFINSIEKYLAVEKEIDSPYLFVYPDT
                     GNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTETSKGQFRDVPFGQGCVDWEELFDV
                     LKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDFLYPLIEKAGLR"
     gene            186652..187368
                     /gene="sgaE"
                     /locus_tag="Sez_0173"
                     /db_xref="GeneID:6760592"
     CDS             186652..187368
                     /gene="sgaE"
                     /locus_tag="Sez_0173"
                     /note="similar to ref|NP_663944.1| L-ribulose-5-phosphate
                     4-epimerase [Streptococcus pyogenes MGAS315]; Probable
                     pentulose-5-phosphate-4-epimerase."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="YP_002122564.1"
                     /db_xref="GI:195977320"
                     /db_xref="GeneID:6760592"
                     /translation="MAKDLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFAARGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPAYIMD
                     KHYLRKHGPNAYYGQKGSLH"
     gene            187665..189317
                     /locus_tag="Sez_0174"
                     /db_xref="GeneID:6760943"
     CDS             187665..189317
                     /locus_tag="Sez_0174"
                     /note="similar to ref|YP_059519.1| Transcription
                     antiterminator, BglG family [Streptococcus pyogenes
                     MGAS10394]; Probable regulator of adjacent sga operon."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator with PTS
                     regulation domain"
                     /protein_id="YP_002122565.1"
                     /db_xref="GI:195977321"
                     /db_xref="GeneID:6760943"
                     /translation="MNVIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHL
                     DKINEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVTDYHYVMKGDERRSLSAIY
                     IAVATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHP
                     MALIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQAS
                     LGKTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKSDFNLIWKRKEYQIAKALAS
                     ELYHNFKLHLDDIEVGMVAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQL
                     HFTHKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQA
                     WQIRLTDDDVAYLTIHLGGELRHSHADQEKTKLVIVSDDGIGIQKLLLKQCQRYLPNC
                     QIEAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPILIVNPILSDDDIIRLIRFSKQG
                     RLSDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            189512..190603
                     /gene="sgaG"
                     /locus_tag="Sez_0175"
                     /db_xref="GeneID:6760591"
     CDS             189512..190603
                     /gene="sgaG"
                     /locus_tag="Sez_0175"
                     /note="similar to ref|YP_601656.1| putative L-ascorbate
                     6-phosphate lactonase [Streptococcus pyogenes MGAS10750];
                     Proposed to catalyze the first step in
                     L-ascorbate-6-phosphate degradation."
                     /codon_start=1
                     /transl_table=11
                     /product="putative L-ascorbate 6-phosphate lactonase"
                     /protein_id="YP_002122566.1"
                     /db_xref="GI:195977322"
                     /db_xref="GeneID:6760591"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            190738..190914
                     /locus_tag="Sez_0176"
                     /db_xref="GeneID:6760942"
     CDS             190738..190914
                     /locus_tag="Sez_0176"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122567.1"
                     /db_xref="GI:195977323"
                     /db_xref="GeneID:6760942"
                     /translation="MLGSLSIGLFAGQESDRSIKSARGGCWVSSQGAKCQKGLLAVVC
                     SGLLSAWLTSDIIA"
     gene            191114..192310
                     /gene="opuAA"
                     /locus_tag="Sez_0177"
                     /db_xref="GeneID:6760589"
     CDS             191114..192310
                     /gene="opuAA"
                     /locus_tag="Sez_0177"
                     /note="similar to ref|NP_268562.1| putative glycine
                     betaine/proline ABC transporter (ATP-binding protein)
                     [Streptococcus pyogenes M1 GAS]; Involved in a
                     multicomponent binding-protein-dependent transport system
                     for glycine betaine. Probably responsible for energy
                     coupling to the transport system."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine transport ATP-binding protein
                     OpuAA"
                     /protein_id="YP_002122568.1"
                     /db_xref="GI:195977324"
                     /db_xref="GeneID:6760589"
                     /translation="MGTILEVKHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSTGSILLEGKDISKMSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            192328..194058
                     /gene="opuAB"
                     /locus_tag="Sez_0178"
                     /db_xref="GeneID:6760951"
     CDS             192328..194058
                     /gene="opuAB"
                     /locus_tag="Sez_0178"
                     /note="similar to ref|YP_601658.1| Glycine betaine-binding
                     protein / Glycine betaine transport system permease
                     protein [Streptococcus pyogenes MGAS10750]; Involved in a
                     multicomponent binding-protein-dependent transport system
                     for glycine betaine; probably responsible for the
                     translocation of the substrate across the membrane."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine transport system permease
                     protein OpuAB"
                     /protein_id="YP_002122569.1"
                     /db_xref="GI:195977325"
                     /db_xref="GeneID:6760951"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNTLMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKSKTVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMSSSSSDKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQRA
                     YSNLADWELIAASTGAMTTSLDQAIKKKEPIVVTAWSPHWIFAKYDLKYLADPKKTFG
                     SKENINTIARKGLKADLPAVHRIVDHFYWTQEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(194284..194433)
                     /locus_tag="Sez_0179"
                     /db_xref="GeneID:6760588"
     CDS             complement(194284..194433)
                     /locus_tag="Sez_0179"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122570.1"
                     /db_xref="GI:195977326"
                     /db_xref="GeneID:6760588"
                     /translation="MQAPASAAHQQLDQRSKLLEEKQMIDLALSARHFYQKETGAKKS
                     DFRDS"
     gene            194597..196318
                     /locus_tag="Sez_0180"
                     /note="IS4-like"
                     /db_xref="GeneID:6762308"
     CDS             194597..196318
                     /locus_tag="Sez_0180"
                     /note="similar to ref|ZP_01371554.1| transposase, IS4
                     [Desulfitobacterium hafniense DCB-2]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS4-like"
                     /protein_id="YP_002122571.1"
                     /db_xref="GI:195977327"
                     /db_xref="GeneID:6762308"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQITKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFMDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKSGNKKSSPVVQEKVLITWSKKYADRERIRREGALDYASQLTNAELFRRT
                     SKKGGKKYLELQYLDKETGEVKPYSPLITIDQEQADFDAQFDGINVLVTSEIEMTDEE
                     MLNAYKELAKIEDCFRVTKTELESRPVYVWTEKHIQAHFLTCFIALVHLRLLQHQIDW
                     QMSPERIITALNSAKVTPLQDNYYRLQESLDMQELNRLLGIEWAKGIVKFEELKHYAK
                     NPYTTLK"
     gene            complement(196423..196572)
                     /locus_tag="Sez_0181"
                     /db_xref="GeneID:6760587"
     CDS             complement(196423..196572)
                     /locus_tag="Sez_0181"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122572.1"
                     /db_xref="GI:195977328"
                     /db_xref="GeneID:6760587"
                     /translation="MQAPASAAHQQLDQRSKLLEEKQMIDLALSARHFYQKETGAKKS
                     DFRDS"
     gene            196567..199266
                     /gene="polA"
                     /locus_tag="Sez_0182"
                     /db_xref="GeneID:6760950"
     CDS             196567..199266
                     /gene="polA"
                     /locus_tag="Sez_0182"
                     /note="similar to ref|YP_001127749.1| DNA polymerase I
                     [Streptococcus pyogenes str. Manfredo]; In addition to
                     polymerase activity, this DNA polymerase exhibits 3' to 5'
                     and 5' to 3' exonuclease activity."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I PolA"
                     /protein_id="YP_002122573.1"
                     /db_xref="GI:195977329"
                     /db_xref="GeneID:6760950"
                     /translation="MQKAKLVRAKQVTVWYNKGMENKNKLLLIDGSSVAFRAFFALYN
                     QIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGR
                     AKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDIIGTLDKMAERTELPFDVTIVSG
                     DKDLIQLTDANTVVEISKKGVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIP
                     GVTKIGEKTGLKLLHEYGSLEGIYQHVDSFKPSKMKENLLHDKEQAFLSKTLATINTS
                     APITIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRA
                     DMFSDDTVFYFEALRDNYHREELIGFAWGNQGQIYASADISLLTTELFKKVLEQPIAT
                     YDFKRSKVLLSHLGLDLPAASYDARLANYLLSTVEDNEMATLARLYTTIPLDTDEVVY
                     GKGVKRAVPDKAVLLGHLARKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAK
                     MEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLP
                     LHLTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRI
                     HTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELR
                     VLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGIS
                     DFGLSNNLGIPRKQAKAYIDTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPD
                     INSRQFNLRSFAERTAINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIV
                     LEVPSHELAAVKELVKETMESAVNLAVPLRVDESAGKSWYEAK"
     gene            199687..200139
                     /locus_tag="Sez_0183"
                     /db_xref="GeneID:6760586"
     CDS             199687..200139
                     /locus_tag="Sez_0183"
                     /note="similar to ref|YP_597771.1| CoA binding protein
                     [Streptococcus pyogenes MGAS10270]; Unknown, COG1832
                     Predicted CoA-binding protein."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-CoA synthetase, alpha subunit-related
                     enzymes"
                     /protein_id="YP_002122574.1"
                     /db_xref="GI:195977330"
                     /db_xref="GeneID:6760586"
                     /translation="MTDTFQNPSDETITSYLESAKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPKLAGQSILGEVVYASLAAIPFAVDIVNVFRRSEYLPQVAQDFLACQA
                     QVFWAQLGLYNQEAEKLLRLAGKADIVMNRCIKIDYLQLITKQDQDSC"
     gene            200176..200649
                     /gene="furR"
                     /locus_tag="Sez_0184"
                     /db_xref="GeneID:6760947"
     CDS             200176..200649
                     /gene="furR"
                     /locus_tag="Sez_0184"
                     /note="similar to ref|YP_279628.1| ferric uptake
                     regulation protein [Streptococcus pyogenes MGAS6180];
                     Regulation of ferric uptake."
                     /codon_start=1
                     /transl_table=11
                     /product="Ferric uptake regulator Fur"
                     /protein_id="YP_002122575.1"
                     /db_xref="GI:195977331"
                     /db_xref="GeneID:6760947"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY"
     gene            201010..202689
                     /locus_tag="Sez_0185"
                     /db_xref="GeneID:6760584"
     CDS             201010..202689
                     /locus_tag="Sez_0185"
                     /note="immunoglobulin G binding protein G precursor;
                     similar to gb|AAQ08491.1| Szp protein [Streptococcus equi
                     subsp. zooepidemicus]; Unknown, possibly involved in
                     immune evasion"
                     /codon_start=1
                     /transl_table=11
                     /product="antiphagocytic M-like protein"
                     /protein_id="YP_002122576.1"
                     /db_xref="GI:195977332"
                     /db_xref="GeneID:6760584"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHVNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASSTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSDKTELRKSIEIAQSKLSQPEGTYSDESLQRLQESVFLGQTYLNS
                     DPDQTTVNSAKATIDSAVSGLVDLTALNTAVETATPLLTDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLTLT
                     SESLKELYNKAIEAAGTFYKTVSEDKKREGISLYELERYTIETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVKPVDPEVKPEPKP
                     EAKKEDKKVADKQQVLPATADRANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            202803..206783
                     /locus_tag="Sez_0186"
                     /db_xref="GeneID:6760949"
     CDS             202803..206783
                     /locus_tag="Sez_0186"
                     /note="similar to dbj|BAF34922.1| dextran-binding lectin A
                     [Streptococcus sobrinus]; Catalysis of the hydrolysis of
                     terminal, non-reducing alpha-D-galactose residues in
                     alpha-D-galactosides, including galactose
                     oligosaccharides, galactomannans and galactohydrolase."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="YP_002122577.1"
                     /db_xref="GI:195977333"
                     /db_xref="GeneID:6760949"
                     /translation="MFKGEDPMFKPYTDGKQRFAIKTFKTGTASVLVATLFLTLGLTT
                     VSADEQQATASAATATALEAEEAANQQTADQSTTAAQDTAAEGSSETLSVTVTANTEA
                     NDSKSQAATAEQATEASTEETTNQEQTEVSQAVETTDKTETKDYIYLSDETRVNPSKV
                     GHGSFLQDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLG
                     VDYSRRGKGDGVSFNIYKSKDGKNWESLVTTGTVTGASEAVYVDLDITGAKYVKLIAN
                     SLKNNGNDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNL
                     ALVLEREFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKT
                     LNALGDLYATNKADLEDKENGYVYKKMMLATAVAYCKEIKSFVVNYGGAYLASDPVLK
                     YQAFKELYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASY
                     TSGYSYTKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLME
                     KGAICWGLSNLGVAVNEVFGIPAVNIYQKGHEAYLVYRQDDQGNGIWDIRDSVYGNRW
                     AISYSRWGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLI
                     ANVYKAGSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAY
                     TYYPQVMVEAIKRITPNISDQAAKAELDMLSYNALLKAKAATDKEVLQSNEVRIIANY
                     ILTGNPIKTASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLT
                     KLNVEDGILVGFDAVSATYRIDLTKAAAPTNSSLYGNDLENRLIGAIEYLEVSLDNGQ
                     SWQAYDGTERFNDNITVLARYQAHGTSLASDSVTYTFTTDSTDATMHYISIDDIQAVT
                     YANEQSGRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNG
                     MIHSAKVDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQ
                     ANKFVSGSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFTITNSG
                     LTAATTEKNQAIQDRILETIKTLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKT
                     TGPLYVLAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAA
                     KTAVNTALMEKLHQLLPGDYFIDLAGLPTSASIDELLDSQLYIYYRESHWTTGYALDR
                     GAFQQL"
     gene            complement(206978..207823)
                     /locus_tag="Sez_0187"
                     /db_xref="GeneID:6760582"
     CDS             complement(206978..207823)
                     /locus_tag="Sez_0187"
                     /note="similar to ref|ZP_00365478.1| COG5523: Predicted
                     integral membrane protein [Streptococcus pyogenes M49
                     591]"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_002122578.1"
                     /db_xref="GI:195977334"
                     /db_xref="GeneID:6760582"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGATYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATTAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLLYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(207856..207999)
                     /locus_tag="Sez_0188"
                     /db_xref="GeneID:6760921"
     CDS             complement(207856..207999)
                     /locus_tag="Sez_0188"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122579.1"
                     /db_xref="GI:195977335"
                     /db_xref="GeneID:6760921"
                     /translation="MHTTYKALSQAVWACLEPYHFIKKSLTCHALKETIALNNDGMGI
                     TGS"
     gene            207978..209186
                     /gene="tgt"
                     /locus_tag="Sez_0189"
                     /db_xref="GeneID:6760581"
     CDS             207978..209186
                     /gene="tgt"
                     /locus_tag="Sez_0189"
                     /note="similar to ref|YP_601664.1| queuine
                     tRNA-ribosyltransferase [Streptococcus pyogenes
                     MGAS10750]; Exchanges the guanine residue with
                     7-aminomethyl-7- deazaguanine in tRNAs with GU(N)
                     anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this
                     exchange, a cyclopentendiol moiety is attached to the
                     7-aminomethyl group of 7-deazaguanine, resulting in the
                     hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-
                     dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-
                     deazaguanosine)."
                     /codon_start=1
                     /transl_table=11
                     /product="queuine tRNA-ribosyltransferase"
                     /protein_id="YP_002122580.1"
                     /db_xref="GI:195977336"
                     /db_xref="GeneID:6760581"
                     /translation="MLCKWYAKRSRLFILIARKKETMTNYPITYRLIKKEKHTGARLG
                     EIITPHGTFPTPMFMPVGTQATVKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARA
                     GGLHKFMNWDQAILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQ
                     NNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAG
                     FEDLRRQSAADLVGMDFPGYSIGGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGA
                     PDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYT
                     CQHYTRAYLRHLLKADETFGMRLTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLER
                     YGYNSSSRNF"
     gene            209617..211005
                     /gene="sclZ.4"
                     /locus_tag="Sez_0190"
                     /db_xref="GeneID:6760953"
     CDS             209617..211005
                     /gene="sclZ.4"
                     /locus_tag="Sez_0190"
                     /note="similar to gb|AAQ91576.1| collagen-like protein 3
                     [Streptococcus equi]; Specific Function:Possible adhesin,
                     has a collagen-structural-motif domain composed of 79
                     Gly-Xaa-Yaa repeats."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein Sclz.4"
                     /protein_id="YP_002122581.1"
                     /db_xref="GI:195977337"
                     /db_xref="GeneID:6760953"
                     /translation="MRNKKTSVRLVQKYGICSAVVALATIASLGGAGNVKAEDFTYPS
                     MYNQGYFFQKFIKNEILKPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPTGPQGLKGEQGPVGPAGPRGERGPQGAQGLRGE
                     RGPAGKDGEAGKPGERGPAGERGPVGPQGPEGKPGQQGPKGDTGPQGEPGQQGPKGDI
                     GPQGPKGDTGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQG
                     EQGLQGPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKSDTGP
                     QGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPKEPETPKASEQ
                     SPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPFFTLAALSVIA
                     SAGVLGLKKKQD"
     gene            212394..212705
                     /locus_tag="Sez_0191"
                     /db_xref="GeneID:6760580"
     CDS             212394..212705
                     /locus_tag="Sez_0191"
                     /note="similar to ref|YP_281540.1| zinc finger protein
                     [Streptococcus pyogenes MGAS5005]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc finger protein"
                     /protein_id="YP_002122582.1"
                     /db_xref="GI:195977338"
                     /db_xref="GeneID:6760580"
                     /translation="MRNCFGIGLDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPSCHKHQDIYFSKE
                     L"
     gene            212709..213248
                     /gene="bioY"
                     /locus_tag="Sez_0192"
                     /db_xref="GeneID:6760955"
     CDS             212709..213248
                     /gene="bioY"
                     /locus_tag="Sez_0192"
                     /note="similar to ref|YP_059530.1| BioY [Streptococcus
                     pyogenes MGAS10394]"
                     /codon_start=1
                     /transl_table=11
                     /product="BioY family protein"
                     /protein_id="YP_002122583.1"
                     /db_xref="GI:195977339"
                     /db_xref="GeneID:6760955"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPMPIVLQNLRVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            213329..214129
                     /locus_tag="Sez_0193"
                     /db_xref="GeneID:6760579"
     CDS             213329..214129
                     /locus_tag="Sez_0193"
                     /note="similar to ref|YP_059531.1| Metal-dependent
                     hydrolase [Streptococcus pyogenes MGAS10394]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="YP_002122584.1"
                     /db_xref="GI:195977340"
                     /db_xref="GeneID:6760579"
                     /translation="MKEGFVMKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGS
                     RSLNELEKEINPLDLDAVMISHYHPDHVADLGVLRHYYQLYPKHLGKPRLLPIYGHDE
                     DEAEFAKLTLPGVSKGIAYQVDGVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLV
                     FTGDTGYFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLT
                     HMPPLPPEGIDPKRHLEVLRQQAQSYAGQIPVDLALPHRTWDLGSLSQ"
     gene            214126..214620
                     /locus_tag="Sez_0194"
                     /db_xref="GeneID:6762144"
     CDS             214126..214620
                     /locus_tag="Sez_0194"
                     /note="similar to ref|YP_001127758.1| putative deaminase
                     [Streptococcus pyogenes str. Manfredo]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-specific adenosine-34 deaminase"
                     /protein_id="YP_002122585.1"
                     /db_xref="GI:195977341"
                     /db_xref="GeneID:6762144"
                     /translation="MSYSKQEQEYFMREALKEAKKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAISEANVHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLETGLLADDCAKLMQTFFQQKRDQKKQDK
                     ESKT"
     gene            complement(214730..215980)
                     /locus_tag="Sez_0195"
                     /db_xref="GeneID:6760578"
     CDS             complement(214730..215980)
                     /locus_tag="Sez_0195"
                     /note="similar to ref|YP_601669.1| S-layer protein /
                     Peptidoglycan endo-beta-N-acetylglucosaminidase
                     [Streptococcus pyogenes MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer homology domain / putative murein
                     endopeptidase"
                     /protein_id="YP_002122586.1"
                     /db_xref="GI:195977342"
                     /db_xref="GeneID:6760578"
                     /translation="MVLTNLSGDDMKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQ
                     FGLTGARRQQVLDQIDQRYYYQQLNQTEKENYLLLYDSLSAFHEVTSLAPASKHSLMK
                     TIDAFMMDNPAFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDNIIADMP
                     ATNDYERVRYFYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYA
                     QAFQFLCQKAGIPVTYIRGSVTFDRSQDAFTHAWNTVQIAGKHYAVDTTFGDPVFDQN
                     ESIKQLEINYNFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLN
                     HSYFTAFDRPDILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQYSDSYHSLFQAY
                     WPNAAGYFYSLHPSTFSISFINYQ"
     gene            complement(216089..217042)
                     /locus_tag="Sez_0196"
                     /note="IS1239"
                     /db_xref="GeneID:6762139"
     CDS             complement(216089..217042)
                     /locus_tag="Sez_0196"
                     /note="similar to ref|ZP_00874436.1| Integrase, catalytic
                     region [Streptococcus suis 89/1591]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS1239"
                     /protein_id="YP_002122587.1"
                     /db_xref="GI:195977343"
                     /db_xref="GeneID:6762139"
                     /translation="MQHYYTPKSKHLTLTERRMIERWLQEELSNREIARRLAKAPQTI
                     HNEVKRGQVRQQVRKGKFEVIYSADFAQKAYQNNRKRSVKQVSLTKELKEKMTHYIKQ
                     KYSPEMMVKAKGIPVPISTIYYWIHHGHLGLTKADMLYPRKEKAKKKHASPNFKPAGK
                     SIEERPESINKRENIGDFEMDTVIQTRAKNECLLTLTDRKSRYQIIRLIPDKSASSVN
                     KALKTILRDYQINSITADNGAEFSRLAEVFDPDHIYYAHPYSSWERGTNENHNRLIRR
                     WLPKGSKNATQQQVAFIENWINNYPKKLFNYKSPKEFLQTG"
     gene            217373..217969
                     /locus_tag="Sez_0197"
                     /db_xref="GeneID:6760577"
     CDS             217373..217969
                     /locus_tag="Sez_0197"
                     /note="similar to emb|CAD33903.1| hypothethical protein
                     [Streptococcus dysgalactiae subsp. equisimilis]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122588.1"
                     /db_xref="GI:195977344"
                     /db_xref="GeneID:6760577"
                     /translation="MYELSHYVEIIISIILVISLLVLTGRLALSLTGIFTIKSGIDTY
                     LQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKDSLLSVIAL
                     AILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRDLMLRHLEE
                     EGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(218113..218238)
                     /locus_tag="Sez_0198"
                     /db_xref="GeneID:6762167"
     CDS             complement(218113..218238)
                     /locus_tag="Sez_0198"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122589.1"
                     /db_xref="GI:195977345"
                     /db_xref="GeneID:6762167"
                     /translation="MSIQLFLRFAYAHQVINPLQKTNDSLSLPVAIASMCLITSS"
     gene            218366..219619
                     /gene="hasA"
                     /locus_tag="Sez_0199"
                     /db_xref="GeneID:6760576"
     CDS             218366..219619
                     /gene="hasA"
                     /locus_tag="Sez_0199"
                     /note="similar to gb|AAQ03572.1|AF414053_1 hyaluronan
                     synthase [Streptococcus equi subsp. zooepidemicus];
                     Glycosaminoglycan synthesis. The hyaluronic acid capsule
                     is involved in the pathogenicity of group A Streptococci;
                     it may be the major virulence determinant."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="YP_002122590.1"
                     /db_xref="GI:195977346"
                     /db_xref="GeneID:6760576"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            219878..221083
                     /gene="hasB"
                     /locus_tag="Sez_0200"
                     /db_xref="GeneID:6762216"
     CDS             219878..221083
                     /gene="hasB"
                     /locus_tag="Sez_0200"
                     /note="similar to gb|AAN65249.1|AF347022_2 UDP-glucose
                     dehydrogenase [Streptococcus equi subsp. zooepidemicus];
                     Catalyzes the formation of UDP-glucuronic acid which is
                     required for capsular hyaluronic acid synthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="YP_002122591.1"
                     /db_xref="GI:195977347"
                     /db_xref="GeneID:6762216"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLGDVIDKV
                     YTRDVFGRD"
     gene            221133..222035
                     /gene="hasC.1"
                     /locus_tag="Sez_0201"
                     /db_xref="GeneID:6760575"
     CDS             221133..222035
                     /gene="hasC.1"
                     /locus_tag="Sez_0201"
                     /note="similar to gb|AAN65250.1|AF347022_3 UDP-glucose
                     pyrophosphorylase [Streptococcus equi subsp.
                     zooepidemicus]; May play a role in stationary phase
                     survival."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase 1
                     HasC.1"
                     /protein_id="YP_002122592.1"
                     /db_xref="GI:195977348"
                     /db_xref="GeneID:6760575"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKAGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTI
                     AVMRVPHEEVSNYGVIAPQGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIF
                     AILEKQAPGAGNEVQLTDAIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKH
                     PQVKDDLTDYIIKLSKQLNKDVKK"
     gene            222202..223581
                     /gene="glmU"
                     /locus_tag="Sez_0202"
                     /db_xref="GeneID:6762135"
     CDS             222202..223581
                     /gene="glmU"
                     /locus_tag="Sez_0202"
                     /note="similar to gb|AAQ05206.1|AF468690_1
                     UDP-N-acetyl-glucosamine pyrophosphorylase [Streptococcus
                     equi subsp. zooepidemicus]; Bifunctional Enzyme
                     Responsible For The Acetylation Of Glc-N-1-P To Give
                     Glcnac-1-P And The Synthesis Of UDP-Glcnac."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional N-acetylglucosamine-1-phosphate
                     uridyltransferase / glucosamine-1-phosphate
                     N-acetyltransferase protein GlmU"
                     /protein_id="YP_002122593.1"
                     /db_xref="GI:195977349"
                     /db_xref="GeneID:6762135"
                     /translation="MKNYAIILAAGKGTRMKSALPKVLHKVSGLSMLEHVLKSVSALA
                     PQKQLTVIGHQAEQVRAVLGEQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGD
                     TPLIRGESLKALLDYHIREKNVATILTANAKDPFGYGRIIRNAAGEVVNIVEQKDANE
                     AEQEVKEINTGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLK
                     DFDESLGVNDRLALAQAEVIMQERINRQHMLNGVTLQNPAATYIESSVEIAPDVLIEA
                     NVTLKGQTRIGSRSVISNGSYILDSRLGEGVVVSQSVIEASVLADGVTVGPYAHIRPD
                     SQLDECVHIGNFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKY
                     QTVIGDHAFIGSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAK
                     RLPHHPNQA"
     gene            223758..225107
                     /gene="gpi"
                     /locus_tag="Sez_0203"
                     /db_xref="GeneID:6760574"
     CDS             223758..225107
                     /gene="gpi"
                     /locus_tag="Sez_0203"
                     /note="similar to gb|AAN65252.1|AF347022_5
                     glucose-6-phosphate isomerase [Streptococcus equi subsp.
                     zooepidemicus]; Involved in glycolysis and in
                     gluconeogenesis."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase Gpi"
                     /protein_id="YP_002122594.1"
                     /db_xref="GI:195977350"
                     /db_xref="GeneID:6760574"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
     gene            225693..226493
                     /gene="sorD"
                     /locus_tag="Sez_0204"
                     /db_xref="GeneID:6762119"
     CDS             225693..226493
                     /gene="sorD"
                     /locus_tag="Sez_0204"
                     /note="similar to ref|NP_720765.1| sorbitol-6-phosphate
                     2-dehydrogenase [Streptococcus mutans UA159]; Fatty acid
                     biosynthesis pathway; first reduction step."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate 2-dehydrogenase SorD"
                     /protein_id="YP_002122595.1"
                     /db_xref="GI:195977351"
                     /db_xref="GeneID:6762119"
                     /translation="MTDWLNISGKTVIVTGGSSGIGQAIVDELLALGVKVANFDIVDN
                     GNRHDHLLFIKVDVTSRQEVEAAVDQVVEHFGTVDALVNNAGINIPRLLVDPKDPHGK
                     YELDDKTFERITMINQKGLYLVSQAVGRILVAKKAGVIINMASEAGLEGSEGQSAYAA
                     TKAAVYSYTRSWAKELGKHGVRVVGIAPGIMEATGLRTLAYEEALGYTRGKTVDQIRA
                     GYASTSTTPLGRSGKLSEVADLVAYYISDRSSYITGITTNVAGGKTRG"
     gene            226516..228384
                     /gene="srlM"
                     /locus_tag="Sez_0205"
                     /db_xref="GeneID:6760571"
     CDS             226516..228384
                     /gene="srlM"
                     /locus_tag="Sez_0205"
                     /note="similar to ref|NP_720766.1| regulator of sorbitol
                     operon [Streptococcus mutans UA159]; Positive regulator of
                     sorbitol operon."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol operon transcription regulator SrlM"
                     /protein_id="YP_002122596.1"
                     /db_xref="GI:195977352"
                     /db_xref="GeneID:6760571"
                     /translation="MTLVNRWYRILEPLVAQNQMAFEELRLQLDVSAQTLAKSIEQLN
                     DILDGDATITQQGAFLQLQVYDYARLETILAGSLRKASDFNSASKRVAYLLKRLLQSS
                     SALVIDDLADEIGVSRSTINKDLKTAKALARSYSVMIQGKPNHGIQAVGTELNLRLLY
                     VHEVYKYFEPQGLSGDSLFFLDELYQTYQLPRKIQELLTKSLAITIERMRQGRYLTDP
                     IPYYSNEVDSNAFMEELVCHIELAYQLSLSQYERQFISFPLNIQYIEGLAYQERPLQE
                     SIVRLYSKMIEQIKASLLVTIDQDKLFVALHTHLKLLVNRLIFHVQANDIFHGEIRYK
                     YPLAFDMANVAAQVLAEEFDCAIELSECSYLALYFEMMMQDAEHVTEPTVKKIAVVCT
                     TGRGTANMICRRLSKVLGPDLLISQFSEEQFNPADNDHYFAIFTTVPLKFGQLKSPVV
                     QITNLFDDQWLQNEWRRVHHYHQKNLTTITLHFARLSKGKAYTDYLIEMAELLEDKQL
                     VDRQFGQRLLEREALQSTLFGNRIAFPHTINDKETKTVLLLGLLDEPYREHDCLVEFI
                     FLVAIPKRVEAQMEADLLDIYDDIFKIASDDKLQAELRGLKNQADFIAFTKEKGVF"
     gene            228393..228845
                     /gene="srlR"
                     /locus_tag="Sez_0206"
                     /db_xref="GeneID:6762054"
     CDS             228393..228845
                     /gene="srlR"
                     /locus_tag="Sez_0206"
                     /note="similar to ref|NP_720767.1| sorbitol operon
                     activator [Streptococcus mutans UA159]; Positive regulator
                     for sorbitol operon expression."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol operon activator SrlR"
                     /protein_id="YP_002122597.1"
                     /db_xref="GI:195977353"
                     /db_xref="GeneID:6762054"
                     /translation="MVIFGLFVIAAYLFQLLLGLRQLKHFNAVYASLRRQGRVAIGRR
                     AGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPLIRR
                     ENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            228993..229538
                     /gene="srlA"
                     /locus_tag="Sez_0207"
                     /db_xref="GeneID:6760570"
     CDS             228993..229538
                     /gene="srlA"
                     /locus_tag="Sez_0207"
                     /note="similar to ref|NP_720768.1| PTS system, sorbitol
                     (glucitol) phosphotransferase enzyme IIC2 [Streptococcus
                     mutans UA159]; The phosphoenolpyruvate-dependent sugar
                     phosphotransferase system (PTS), a major carbohydrate
                     active -transport system, catalyzes the phosphorylation of
                     incoming sugar substrates concomitant with their
                     translocation across the cell membrane. This system is
                     involved in glucitol/sorbitol transport."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol/sorbitol permease IIC component SrlA"
                     /protein_id="YP_002122598.1"
                     /db_xref="GI:195977354"
                     /db_xref="GeneID:6760570"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKTIEL"
     gene            229551..230543
                     /gene="srlE"
                     /locus_tag="Sez_0208"
                     /db_xref="GeneID:6762045"
     CDS             229551..230543
                     /gene="srlE"
                     /locus_tag="Sez_0208"
                     /note="similar to ref|NP_720769.1| PTS system, sorbitol
                     phosphotransferase enzyme IIBC [Streptococcus mutans
                     UA159]; The phosphoenolpyruvate-dependent sugar
                     phosphotransferase system (PTS), a major carbohydrate
                     active -transport system, catalyzes the phosphorylation of
                     incoming sugar substrates concomitant with their
                     translocation across the cell membrane. This system is
                     involved in glucitol/sorbitol transport."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system, glucitol/sorbitol-specific IIB
                     component and second of two IIC components SrlE"
                     /protein_id="YP_002122599.1"
                     /db_xref="GI:195977355"
                     /db_xref="GeneID:6762045"
                     /translation="MMTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIV
                     DKIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGP
                     LAQYITEDIYVSAVGLEQITASDAQAQTIKPEPVAPKAASYDTNKKITEQRAENSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            230631..230942
                     /gene="srlB"
                     /locus_tag="Sez_0209"
                     /db_xref="GeneID:6760569"
     CDS             230631..230942
                     /gene="srlB"
                     /locus_tag="Sez_0209"
                     /note="similar to ref|NP_720770.1| putative PTS system,
                     sorbitol-specific enzyme IIA [Streptococcus mutans UA159];
                     The phosphoenolpyruvate-dependent sugar phosphotransferase
                     system (PTS), a major carbohydrate active -transport
                     system, catalyzes the phosphorylation of incoming sugar
                     substrates concomitant with their translocation across the
                     cell membrane. This system is involved in
                     glucitol/sorbitol transport."
                     /codon_start=1
                     /transl_table=11
                     /product="Glucitol/sorbitol-specific phosphotransferase
                     enzyme IIA component SrlB"
                     /protein_id="YP_002122600.1"
                     /db_xref="GI:195977356"
                     /db_xref="GeneID:6760569"
                     /translation="MINAANMLILFGQGAPADLADFCYTIDNKQVSGSISVGGQLVID
                     QMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLHVKGKGLPQVRQGSLVQIF
                     A"
     gene            231454..232884
                     /locus_tag="Sez_0210"
                     /db_xref="GeneID:6761995"
     CDS             231454..232884
                     /locus_tag="Sez_0210"
                     /note="similar to ref|ZP_02184619.1| cassette chromosome
                     recombinase B1 [Carnobacterium sp. AT7]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS663-like"
                     /protein_id="YP_002122601.1"
                     /db_xref="GI:195977357"
                     /db_xref="GeneID:6761995"
                     /translation="MNTLDERVFENFYHEVGRPSYHPKMLLASLLFAYSQGIFSGRKI
                     EKMMSETITMQYLTGQLVVSYRTINRFRVTTGMEDLTRDLFIDFNLRLKMEELVTLDC
                     LYIDGTKIEANANKYSFVWKKATDKFSAKLQTKLKSYFQEEITPLIQKAIILDEEEPV
                     TSQQLSEFAQLLEDELQAVNQTIEENPIKGKDERKTKRRKLKKVLRKVTDDFSVRAKK
                     YETHQETFEGRNSFSKTDTDATFMRRKEDHMKNGQLKAGYNLQLATENQFVLHYDVFP
                     NQADTKTLLPFFETYPHDLKIVVADAGYGSEENLLRLDESNVNHLMKYAMFDKEQKKR
                     DKQSARNLANWHYDDKEDRYTHPDGWCYRFHHIKHTKTQTGFEQEIKVYYADDPESTP
                     QKGCYINERYQQLKAKEYQALLSPEGRRIFAQRKIDVEPVFRQIKACLGYKRCHLRGK
                     RQVKIDMGLVLMANNLLKYNRRTAQN"
     gene            233037..234323
                     /locus_tag="Sez_0211"
                     /db_xref="GeneID:6760568"
     CDS             233037..234323
                     /locus_tag="Sez_0211"
                     /note="similar to ref|ZP_00513513.1| abortive infection
                     protein, putative [Crocosphaera watsonii WH8501]"
                     /codon_start=1
                     /transl_table=11
                     /product="abortive phage resistance protein"
                     /protein_id="YP_002122602.1"
                     /db_xref="GI:195977358"
                     /db_xref="GeneID:6760568"
                     /translation="MLIEFKVKNFTSFKKEATFSMVSSEKLNELLDNRIEMENDFHLL
                     KAASIFGANASGKSNLLKALGFMVAFIERSMRDSQEGKRNFKNLTFSLDNESKDKATD
                     FEISFLMENQIVTYNFSLYKGDIASESLTVDDLEIFRRDASGIVTYSEKIFHTKDELN
                     LKFSLTNSNSLFLTVLSVTNTKLAEDIIKYLTGNITFLSGYGNNAKFTKTVIKEDDSY
                     KIKVLDLLKVADFNITGLDVKQHEFEIKPLGQSDEEIPEEARDKANRLLSKHNIYDSK
                     GMIVDNKLFDVDSFESSGTRVFLSLAGPIISVLEKGGVLIIDEADALLHPLVTKYLIE
                     LFNTTENSKSQLIITSHNSNILDQELLRRDQIWFVEKDELEVSHLTSLSEYKFNGSVV
                     RSDERYAKNYLRGKYGAIPYIKNDMIHNIFKSGLGD"
     gene            234330..234965
                     /locus_tag="Sez_0212"
                     /db_xref="GeneID:6761929"
     CDS             234330..234965
                     /locus_tag="Sez_0212"
                     /note="similar to ref|ZP_01628459.1| hypothetical protein
                     N9414_15200 [Nodularia spumigena CCY9414]"
                     /codon_start=1
                     /transl_table=11
                     /product="abortive phage resistance protein"
                     /protein_id="YP_002122603.1"
                     /db_xref="GI:195977359"
                     /db_xref="GeneID:6761929"
                     /translation="MGKNKFSRDKKTGKKEQLPIILIVCEGEKTEPNYFKQFEVASVK
                     IEARGIGDNTRRLVKYAIEESKKGSYDQVWCVFDKDSFPDNDFNTAVDLARNKNCGIA
                     YSNESFELWYILHFEYLNSQIGRDSYIDKLNKIFKSKQSEGFPDSYKKNDSNIYRMLK
                     PYQNTALKNAKRLSQDYQSEATPSAAQQFPVTYVYKLVEELNRWIPSNRLD"
     gene            complement(235389..236399)
                     /gene="sclZ.5"
                     /locus_tag="Sez_0213"
                     /db_xref="GeneID:6760567"
     CDS             complement(235389..236399)
                     /gene="sclZ.5"
                     /locus_tag="Sez_0213"
                     /note="similar to gb|AAQ91579.1| collagen-like protein 3
                     [Streptococcus equi]; Possible adhesin, has a
                     collagen-structural-motif domain composed of 61
                     Gly-Xaa-Yaa repeats."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like surface protein SclZ.5"
                     /protein_id="YP_002122604.1"
                     /db_xref="GI:195977360"
                     /db_xref="GeneID:6760567"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGDQGQKGEKGDQG
                     QKGEKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGQKGE
                     KGDQGQKGEKGDQGQKGEKGDQSQKGEKGQRGEQGQKGEKGDQGIQGQGEHGHKGHHG
                     KDAKPSAPKADSKSTAKAMAPAAQKGTLPATGETNHPFFTLAALGVIASAGMLTLKGK
                     KN"
     gene            237046..237579
                     /locus_tag="Sez_0214"
                     /db_xref="GeneID:6761868"
     CDS             237046..237579
                     /locus_tag="Sez_0214"
                     /note="similar to ref|YP_821136.1|
                     5-formyltetrahydrofolate cyclo-ligase [Streptococcus
                     thermophilus LMD-9]; Catalysis of the reaction: ATP +
                     5-formyltetrahydrofolate = ADP + phosphate +
                     5,10-methenyltetrahydrofolate."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase family
                     protein"
                     /protein_id="YP_002122605.1"
                     /db_xref="GI:195977361"
                     /db_xref="GeneID:6761868"
                     /translation="MGMIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEA
                     QTLATYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFDLM
                     EPRSTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWE
                     DFVVEAHDIAVKEVYCQ"
     gene            237576..238259
                     /locus_tag="Sez_0215"
                     /db_xref="GeneID:6760566"
     CDS             237576..238259
                     /locus_tag="Sez_0215"
                     /note="similar to ref|YP_059541.1| integral membrane
                     protein (Rhomboid family) [Streptococcus pyogenes
                     MGAS10394]"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein (Rhomboid family)"
                     /protein_id="YP_002122606.1"
                     /db_xref="GI:195977362"
                     /db_xref="GeneID:6760566"
                     /translation="MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGG
                     MNGLVVRAMPGQLWRLVTPIVVHIGFGHFFINALTLYFVGRLAESIWGSRQFLLLYVC
                     SGIMGNAFIMWLTPDIVAAGASTSLFGLFAAIAVLGIGGNNHSLRELGRSYQALIVMN
                     LLLNLFMPNVSIAGHLGGVVGGGLCGVALSNQLPDQAFSSRQRRLAALAYVVIVVGIV
                     SRSFLSLAS"
     gene            complement(238548..239516)
                     /gene="hasC.2"
                     /locus_tag="Sez_0216"
                     /db_xref="GeneID:6761859"
     CDS             complement(238548..239516)
                     /gene="hasC.2"
                     /locus_tag="Sez_0216"
                     /note="similar to gb|AAQ05209.1|AF468691_2 UDP-glucose
                     pyrophosphorylase [Streptococcus equi subsp.
                     zooepidemicus]; Catalysis of the reaction: UTP +
                     alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC.2"
                     /protein_id="YP_002122607.1"
                     /db_xref="GI:195977363"
                     /db_xref="GeneID:6761859"
                     /translation="MNFAQKTNGTHKEPQIKEELMTKVRKAIIPAAGLGTRFLPATKA
                     LAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKG
                     KTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNPS
                     AKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAPQGKAVKGLYSVETFVEKPSP
                     DEAPSDLAIIGRYLLTPEIFAILEKQAPGAGNEVQLTDAIDKLNKTQRVFAREFKGER
                     YDVGDKFGFMKTSLDYALKHPQVKDDLTDYIIKLGKALESTQQQTK"
     gene            complement(239482..240501)
                     /locus_tag="Sez_0217"
                     /db_xref="GeneID:6760565"
     CDS             complement(239482..240501)
                     /locus_tag="Sez_0217"
                     /note="similar to ref|YP_279657.1| NAD(P)H-dependent
                     glycerol-3-phosphate dehydrogenase [Streptococcus pyogenes
                     MGAS6180]; De novo phospholipid biosynthesis; glycerol-3
                     phosphate formation."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase (NAD(P)+)"
                     /protein_id="YP_002122608.1"
                     /db_xref="GI:195977364"
                     /db_xref="GeneID:6760565"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     NHTNSHYFKDIVLDEAIKATLDLKEALADADAILFVVPTKVTRLVAKQVAQVLDHKAV
                     VMHASKGLEPGTHERLSTILEEEISAQLRSEIVVVSGPSHAEETIVRDITLITAASKD
                     ITAAKYVQALFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     SNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHS"
     gene            complement(240580..240717)
                     /locus_tag="Sez_0218"
                     /db_xref="GeneID:6761823"
     CDS             complement(240580..240717)
                     /locus_tag="Sez_0218"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122609.1"
                     /db_xref="GI:195977365"
                     /db_xref="GeneID:6761823"
                     /translation="MAFPSSLVLMITILVLLGTIVNQKGLRSDYLPFYLPFASTTKLT
                     G"
     gene            240711..241160
                     /locus_tag="Sez_0219"
                     /db_xref="GeneID:6760564"
     CDS             240711..241160
                     /locus_tag="Sez_0219"
                     /note="similar to ref|YP_599803.1| Transcriptional
                     regulator, MarR family [Streptococcus pyogenes MGAS2096]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MarR family"
                     /protein_id="YP_002122610.1"
                     /db_xref="GI:195977366"
                     /db_xref="GeneID:6760564"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            241153..242862
                     /locus_tag="Sez_0220"
                     /db_xref="GeneID:6761806"
     CDS             241153..242862
                     /locus_tag="Sez_0220"
                     /note="similar to ref|YP_001127771.1| ABC transporter
                     ATP-binding membrane protein [Streptococcus pyogenes str.
                     Manfredo]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance ABC transporter ATP-binding
                     and permease protein"
                     /protein_id="YP_002122611.1"
                     /db_xref="GI:195977367"
                     /db_xref="GeneID:6761806"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DKTRIAEVGFWLLVIAGIGLVSGAVNTVLSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDKFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIFLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PTISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            242862..244658
                     /locus_tag="Sez_0221"
                     /db_xref="GeneID:6760563"
     CDS             242862..244658
                     /locus_tag="Sez_0221"
                     /note="similar to ref|NP_268592.1| putative ABC
                     transporter (ATP-binding protein) [Streptococcus pyogenes
                     M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance ABC transporter ATP-binding
                     and permease protein"
                     /protein_id="YP_002122612.1"
                     /db_xref="GI:195977368"
                     /db_xref="GeneID:6760563"
                     /translation="MKTLRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLTYLFIAAANLIYSLLFTR
                     IISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQEEAIEGFVEHNERVRSATFKGRLFAGLLFPVMNGMSLVNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGASRI
                     QEMFDEKEEVRPEHAPVFTTLKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQEEVETAARATHIHDFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGNHHELLRQKGFYAELYHNQFVFE"
     gene            244820..245587
                     /locus_tag="Sez_0222"
                     /db_xref="GeneID:6761675"
     CDS             244820..245587
                     /locus_tag="Sez_0222"
                     /note="similar to ref|NP_663969.1| hypothetical protein
                     SpyM3_0165 [Streptococcus pyogenes MGAS315]; Possibly
                     invovlved in DNA integration/recombination/invertion."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122613.1"
                     /db_xref="GI:195977369"
                     /db_xref="GeneID:6761675"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKAWAREDVRPKILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFAKTVRGLEKEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKI
                     QGVDLVQVKKDAKVFLADKDLEADFPRIRFSYAGKEI"
     gene            245767..246213
                     /gene="dut"
                     /locus_tag="Sez_0223"
                     /db_xref="GeneID:6760562"
     CDS             245767..246213
                     /gene="dut"
                     /locus_tag="Sez_0223"
                     /note="similar to gb|AAL97006.1| putative dUTPase, phage
                     associated [Streptococcus pyogenes MGAS8232]; This enzyme
                     is involved in nucleotide metabolism:it produces dUMP, the
                     immediate precursor of thymidine nucleotides and it
                     decreases the intracellular concentration of dUTP so that
                     uracil cannot be incorporated into DNA."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="YP_002122614.1"
                     /db_xref="GI:195977370"
                     /db_xref="GeneID:6760562"
                     /translation="MTKIRGFELVSGFTDTELLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYNNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQASGERTGGFGSTGR"
     gene            246279..247640
                     /gene="radA"
                     /locus_tag="Sez_0224"
                     /db_xref="GeneID:6761723"
     CDS             246279..247640
                     /gene="radA"
                     /locus_tag="Sez_0224"
                     /note="similar to ref|NP_606508.1| DNA repair protein RadA
                     [Streptococcus pyogenes MGAS8232]; May play a role in the
                     repair of endogenous alkylation damage."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA-like"
                     /protein_id="YP_002122615.1"
                     /db_xref="GI:195977371"
                     /db_xref="GeneID:6761723"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHVNGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDIPSGIEVVGVMTVGEVLKA
                     VFA"
     gene            248407..248913
                     /locus_tag="Sez_0225"
                     /db_xref="GeneID:6760561"
     CDS             248407..248913
                     /locus_tag="Sez_0225"
                     /note="similar to ref|YP_821127.1| Carbonic anhydrase
                     [Streptococcus thermophilus LMD-9]; Carbonate hydro-lyase
                     (carbon-dioxide-forming)."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="YP_002122616.1"
                     /db_xref="GI:195977372"
                     /db_xref="GeneID:6760561"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILHQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            249041..249754
                     /locus_tag="Sez_0226"
                     /db_xref="GeneID:6761557"
     CDS             249041..249754
                     /locus_tag="Sez_0226"
                     /note="similar to ref|YP_279665.1| hypothetical protein
                     M28_Spy0196 [Streptococcus pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH DNA-binding protein"
                     /protein_id="YP_002122617.1"
                     /db_xref="GI:195977373"
                     /db_xref="GeneID:6761557"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGSH"
     gene            250356..251801
                     /gene="gltX"
                     /locus_tag="Sez_0227"
                     /db_xref="GeneID:6760560"
     CDS             250356..251801
                     /gene="gltX"
                     /locus_tag="Sez_0227"
                     /note="similar to ref|NP_268598.1| glutamyl-tRNA
                     synthetase [Streptococcus pyogenes M1 GAS]; Catlysis of
                     the reaction: ATP + L-glutamate + tRNA(Glu) = AMP +
                     diphosphate + L-glutamyl-tRNA(Glu)."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA synthetase; Glutamyl-tRNA(Gln)
                     synthetase"
                     /protein_id="YP_002122618.1"
                     /db_xref="GI:195977374"
                     /db_xref="GeneID:6760560"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFVIRIE
                     DTDRKRHVEDGERSQLENLRWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSADEKAAYIAEREAAGIVPTVRLAV
                     NEAGIYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDESRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            252244..253590
                     /gene="fasB"
                     /locus_tag="Sez_0228"
                     /db_xref="GeneID:6761607"
     CDS             252244..253590
                     /gene="fasB"
                     /locus_tag="Sez_0228"
                     /note="similar to ref|YP_597813.1| Sensory transduction
                     protein kinase FasB [Streptococcus pyogenes MGAS10270]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensory transduction protein kinase FasB"
                     /protein_id="YP_002122619.1"
                     /db_xref="GI:195977375"
                     /db_xref="GeneID:6761607"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLMIDPFLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGGYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDSFLDLKSPMMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     YLKHELKKEQQAYIANLETYGKHLEKLYKGVKVFQLDYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDWI
                     RDSYISELDLLLLVSIFCDNAIEAALETARPAVAIAYFLSDNQQIFTVTNTTKDERVM
                     INKIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            253602..254900
                     /gene="fasC"
                     /locus_tag="Sez_0229"
                     /db_xref="GeneID:6760558"
     CDS             253602..254900
                     /gene="fasC"
                     /locus_tag="Sez_0229"
                     /note="similar to ref|YP_597814.1| Sensory transduction
                     protein kinase FasC [Streptococcus pyogenes MGAS10270]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensory transduction protein kinase FasC"
                     /protein_id="YP_002122620.1"
                     /db_xref="GI:195977376"
                     /db_xref="GeneID:6760558"
                     /translation="MLGMSFFYALIFVNSWVIFLTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDNGDIAAISKVYQTVIQESA
                     SSMRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPEMLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            254904..255644
                     /gene="fasA"
                     /locus_tag="Sez_0230"
                     /db_xref="GeneID:6761560"
     CDS             254904..255644
                     /gene="fasA"
                     /locus_tag="Sez_0230"
                     /note="similar to gb|AAL78045.1| response regulator FasA
                     [Streptococcus dysgalactiae subsp. equisimilis]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator FasA"
                     /protein_id="YP_002122621.1"
                     /db_xref="GI:195977377"
                     /db_xref="GeneID:6761560"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            256477..256686
                     /locus_tag="Sez_0231"
                     /db_xref="GeneID:6760557"
     CDS             256477..256686
                     /locus_tag="Sez_0231"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122622.1"
                     /db_xref="GI:195977378"
                     /db_xref="GeneID:6760557"
                     /translation="MVLNIFDSIDLYLSNKHTTTVRNHAALFWIFVLLIVFYFGYAYY
                     CTSRGYNFSGIANFFSGGVNIGCYR"
     gene            256836..257543
                     /locus_tag="Sez_0232"
                     /db_xref="GeneID:6761501"
     CDS             256836..257543
                     /locus_tag="Sez_0232"
                     /note="similar to ref|NP_816714.1| ABC transporter,
                     ATP-binding protein [Enterococcus faecalis V583]; Involved
                     in transport."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter, ATP-binding protein"
                     /protein_id="YP_002122623.1"
                     /db_xref="GI:195977379"
                     /db_xref="GeneID:6761501"
                     /translation="MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFL
                     DSVAGIIQYDKGNVSLDGHASGSDAFKTNSFYIPSDSYLPEYLTGREYAAFIQSRYAN
                     ANGSVFVELSRLLDMTEALDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDL
                     ETVILIQELFSLYAREHKLLLVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYI
                     YQKGRITEKLQRIAEIL"
     gene            257548..258897
                     /locus_tag="Sez_0233"
                     /note="orf_0233"
                     /db_xref="GeneID:6760556"
     CDS             257548..258897
                     /locus_tag="Sez_0233"
                     /note="similar to ref|NP_816713.1| hypothetical protein
                     EF3103 [Enterococcus faecalis V583]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122624.1"
                     /db_xref="GI:195977380"
                     /db_xref="GeneID:6760556"
                     /translation="MSFYYNDALNGFLNRPFFKKKKNQYLVAIVGFVLYFGYFLANVR
                     EIGRLGFGARQLDTETLIALTRLTIMSYINMCLIISIALFVFVNSVISLTKSSVYITN
                     ILPYSKREILIAQKIFKMGVALIGYEALLLLVFPLFGQLPIIKLSDQFLLLLLFHVLF
                     IAVFLIVDACYAVLARVAARYKKCSIGSLVFGLDIFFTLFCVAYLVYFKTGIDTFIGK
                     LPIGLTALIVLALLIASFVLIVVSQLSYRYALTIQYYKKSSYGLVRLPMIRLNLMTTF
                     PAIYRHKSFIHSLALITVFSLIISYQLGLKSGLETFANLNALLTFSAVNYADATAKIR
                     KYYHFFRVSLKEEVLSLVLGGIVVSMAPFLISLYFGGSMLAFFLSMAIYLCAVIAGLL
                     FPTTQGNLNEAASTTTTIFLSIALYLILKHDSLYISSAILSVLVLVLSVCLARERRG"
     gene            259174..259539
                     /locus_tag="Sez_0234"
                     /db_xref="GeneID:6761447"
     CDS             259174..259539
                     /locus_tag="Sez_0234"
                     /note="similar to ref|NP_816711.1| hypothetical protein
                     EF3101 [Enterococcus faecalis V583]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122625.1"
                     /db_xref="GI:195977381"
                     /db_xref="GeneID:6761447"
                     /translation="MTTVELVLQLPLALLTIALHELLHYLVAYLLGYKPKFGWERKLI
                     PFVSFPNKNRDIDNLLIALAAPVGLFVIGMLIPRSIAFLSLVRIICLLNILHVFPWCT
                     DGQVILLSLIHCCQKGGRV"
     gene            259548..260039
                     /locus_tag="Sez_0235"
                     /db_xref="GeneID:6760555"
     CDS             259548..260039
                     /locus_tag="Sez_0235"
                     /note="similar to ref|NP_816709.1| transporter accessory
                     protein, putative [Enterococcus faecalis V583]"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter accessory protein"
                     /protein_id="YP_002122626.1"
                     /db_xref="GI:195977382"
                     /db_xref="GeneID:6760555"
                     /translation="MKALAIGIVMVICLVGGYYWAIGKAKKPAYAVNTPQFIHERPDV
                     VLRRLENGEQGVYYFGFADCPWCVELLPVLDEALAVSDLQAYAVDTKGKDFTETLRSR
                     LSRFYARYYQNHLSVPFLVTILEDGKVQTHVGTLEKHNAHEEPLTDKQKKELKKIVLA
                     LLR"
     gene            260270..260629
                     /gene="rnpA"
                     /locus_tag="Sez_0236"
                     /db_xref="GeneID:6761373"
     CDS             260270..260629
                     /gene="rnpA"
                     /locus_tag="Sez_0236"
                     /note="similar to ref|YP_001127781.1| ribonuclease P
                     [Streptococcus pyogenes str. Manfredo]; RNaseP catalyzes
                     the removal of the 5'-leader sequence from pre-tRNA to
                     produce the mature 5'terminus. It can also cleave other
                     RNA substrates such as 4.5S RNA. The protein component
                     plays an auxiliary but essential role in vivo by binding
                     to the 5'- leader sequence and broadening the substrate
                     specificity of the ribozyme."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component RnpA"
                     /protein_id="YP_002122627.1"
                     /db_xref="GI:195977383"
                     /db_xref="GeneID:6761373"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKTEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            260613..261422
                     /gene="oxaA1"
                     /locus_tag="Sez_0237"
                     /db_xref="GeneID:6760554"
     CDS             260613..261422
                     /gene="oxaA1"
                     /locus_tag="Sez_0237"
                     /note="similar to ref|YP_001127782.1| membrane protein
                     OxaA 1 precursor [Streptococcus pyogenes str. Manfredo];
                     Required for the insertion of integral membrane proteins
                     into the membrane. May also be involved in protein
                     secretion processes."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein OxaA 1 precursor"
                     /protein_id="YP_002122628.1"
                     /db_xref="GI:195977384"
                     /db_xref="GeneID:6760554"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            261434..262333
                     /gene="jag"
                     /locus_tag="Sez_0238"
                     /db_xref="GeneID:6761441"
     CDS             261434..262333
                     /gene="jag"
                     /locus_tag="Sez_0238"
                     /note="similar to ref|YP_595942.1| jag protein
                     [Streptococcus pyogenes MGAS9429]; RNA binding"
                     /codon_start=1
                     /transl_table=11
                     /product="Jag protein"
                     /protein_id="YP_002122629.1"
                     /db_xref="GI:195977385"
                     /db_xref="GeneID:6761441"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRGVPEEINRQNAPVVNPDEVELEELKAVRSEGKRA
                     AQSVAHQSINPSSTDQSVPAQSKAQPALSAAGMSQLDPAAADTSKDIELAAQEVSDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            262455..262688
                     /locus_tag="Sez_0239"
                     /db_xref="GeneID:6760553"
     CDS             262455..262688
                     /locus_tag="Sez_0239"
                     /note="similar to gb|EAY64209.1| conserved hypothetical
                     protein [Burkholderia cenocepacia PC184]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122630.1"
                     /db_xref="GI:195977386"
                     /db_xref="GeneID:6760553"
                     /translation="MKLSILWKSKVLGFMSLIGLFLASSLAVEQGEYYLVREEGGIAV
                     QRVVYKLPNELFQLLESGRKSLLEIDFYVKNNC"
     gene            262860..263282
                     /locus_tag="Sez_0240"
                     /db_xref="GeneID:6761418"
     CDS             262860..263282
                     /locus_tag="Sez_0240"
                     /note="similar to ref|ZP_00230000.1| hypothetical protein
                     LMOh7858_0095 [Listeria monocytogenes str. 4b H7858]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122631.1"
                     /db_xref="GI:195977387"
                     /db_xref="GeneID:6761418"
                     /translation="MGITQMTWEEYETFNKVETSHNFYIREHNGTYYTVFELGIASVR
                     RIFELSAADFEEYLKGLRTADEILFKVQNDCWPPTEEEKNRIMRERAKDRPMVLISNP
                     KNQMLFTQEELSKLIPIAEQKWINWKGKLPDDYISPLK"
     gene            263812..264522
                     /gene="nanE"
                     /locus_tag="Sez_0241"
                     /db_xref="GeneID:6760552"
     CDS             263812..264522
                     /gene="nanE"
                     /locus_tag="Sez_0241"
                     /note="similar to ref|NP_663983.1|
                     N-acetylmannosamine-6-phosphate 2-epimerase [Streptococcus
                     pyogenes MGAS315]; Converts
                     N-acetylmannosamine-6-phosphate (ManNAc-6-P) to
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative N-acetylmannosamine-6-phosphate
                     2-epimerase NanE"
                     /protein_id="YP_002122632.1"
                     /db_xref="GI:195977388"
                     /db_xref="GeneID:6760552"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKDYPPQSPFITPTMAEVDALVALDV
                     AVIALDCTQRERHDGLAIADFIRAIKEKYPDQLFMADISTLEEGLAAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELIGALCEAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVVALKKEE"
     gene            264527..266038
                     /gene="ptsG"
                     /locus_tag="Sez_0242"
                     /db_xref="GeneID:6761392"
     CDS             264527..266038
                     /gene="ptsG"
                     /locus_tag="Sez_0242"
                     /note="similar to ref|YP_001198767.1| Phosphotransferase
                     system IIC component,
                     glucose/maltose/N-acetylglucosamine-specific
                     [Streptococcus suis 05ZYH33]; The
                     phosphoenolpyruvate-dependent sugar phosphotransferase
                     system (PTS), a major carbohydrate active -transport
                     system, catalyzes the phosphorylation of incoming sugar
                     substrates concomitant with their translocation across the
                     cell membrane. This system is involved in glucose
                     transport."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system glucose-specific EIICBA component"
                     /protein_id="YP_002122633.1"
                     /db_xref="GI:195977389"
                     /db_xref="GeneID:6761392"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTSAQGSSLREASLAIIEALGGPANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            266040..266555
                     /gene="ptsG"
                     /locus_tag="Sez_0243"
                     /db_xref="GeneID:6760551"
     CDS             266040..266555
                     /gene="ptsG"
                     /locus_tag="Sez_0243"
                     /note="similar to ref|YP_603278.1| PTS system,
                     glucose-specific IIABC component [Streptococcus pyogenes
                     MGAS10750]; The phosphoenolpyruvate-dependent sugar
                     phosphotransferase system (PTS), a major carbohydrate
                     active -transport system, catalyzes the phosphorylation of
                     incoming sugar substrates concomitant with their
                     translocation across the cell membrane. This system is
                     involved in glucose transport."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system, maltose and glucose-specific IIA-B-C
                     component"
                     /protein_id="YP_002122634.1"
                     /db_xref="GI:195977390"
                     /db_xref="GeneID:6760551"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAVMPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLVHIGIDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVDLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAAKA
                     EVGQVRLKATL"
     gene            266959..267093
                     /gene="rpmH"
                     /locus_tag="Sez_0244"
                     /db_xref="GeneID:6761386"
     CDS             266959..267093
                     /gene="rpmH"
                     /locus_tag="Sez_0244"
                     /note="similar to ref|ZP_00790322.1| ribosomal protein L34
                     [Streptococcus agalactiae 515]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="YP_002122635.1"
                     /db_xref="GI:195977391"
                     /db_xref="GeneID:6761386"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA"
     gene            267380..268105
                     /gene="nanE"
                     /locus_tag="Sez_0245"
                     /db_xref="GeneID:6760550"
     CDS             267380..268105
                     /gene="nanE"
                     /locus_tag="Sez_0245"
                     /note="similar to ref|YP_597820.1|
                     N-acetylmannosamine-6-phosphate 2-epimerase [Streptococcus
                     pyogenes MGAS10270]; Converts
                     N-acetylmannosamine-6-phosphate (ManNAc-6-P) to
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative N-acetylmannosamine-6-phosphate
                     2-epimerase NanE"
                     /protein_id="YP_002122636.1"
                     /db_xref="GI:195977392"
                     /db_xref="GeneID:6760550"
                     /translation="MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMVEVDALAALGV
                     AVIALDCTQRERHDGLAIVDFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALTSSLSIKKY"
     gene            268124..269437
                     /locus_tag="Sez_0246"
                     /db_xref="GeneID:6761364"
     CDS             268124..269437
                     /locus_tag="Sez_0246"
                     /note="similar to ref|YP_279676.1|
                     N-acetylneuraminate-binding protein [Streptococcus
                     pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein -
                     sugar transport"
                     /protein_id="YP_002122637.1"
                     /db_xref="GI:195977393"
                     /db_xref="GeneID:6761364"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDDFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDKRMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            269559..270425
                     /locus_tag="Sez_0247"
                     /db_xref="GeneID:6760549"
     CDS             269559..270425
                     /locus_tag="Sez_0247"
                     /note="similar to ref|YP_597823.1| N-acetylneuraminate
                     transport system permease protein [Streptococcus pyogenes
                     MGAS10270]; Probably part of the binding-protein-dependent
                     transport system yurMNO. Probably responsible for the
                     translocation of the substrate across the membrane."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter, N-acetylneuraminate transport
                     system permease protein"
                     /protein_id="YP_002122638.1"
                     /db_xref="GI:195977394"
                     /db_xref="GeneID:6760549"
                     /translation="MRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNYTMTDFTF
                     VGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVISRSFYRAV
                     FFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWALLAIIVIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTLYITVITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAILIALISF
                     AQFKFLGNDVEY"
     gene            270438..271268
                     /locus_tag="Sez_0248"
                     /db_xref="GeneID:6760872"
     CDS             270438..271268
                     /locus_tag="Sez_0248"
                     /note="similar to ref|NP_663987.1| putative sugar
                     transport protein (permease) [Streptococcus pyogenes
                     MGAS315]; Part of the binding-protein-dependent transport
                     system for L-arabinose. Probably responsible for the
                     translocation of the substrate across the membrane."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter membrane-spanning permease -
                     sugar transport"
                     /protein_id="YP_002122639.1"
                     /db_xref="GI:195977395"
                     /db_xref="GeneID:6760872"
                     /translation="MKKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSVFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG"
     gene            271295..271750
                     /locus_tag="Sez_0249"
                     /db_xref="GeneID:6760548"
     CDS             271295..271750
                     /locus_tag="Sez_0249"
                     /note="similar to ref|NP_606523.1| hypothetical protein
                     spyM18_0238 [Streptococcus pyogenes MGAS8232]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122640.1"
                     /db_xref="GI:195977396"
                     /db_xref="GeneID:6760548"
                     /translation="MLYDVLENIRRYKGIHHHLDLAIDFLMTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDRFCYFFPNEAHQPNGFNDGGDTVTKCLIKVLMED"
     gene            271775..272425
                     /locus_tag="Sez_0250"
                     /db_xref="GeneID:6760870"
     CDS             271775..272425
                     /locus_tag="Sez_0250"
                     /note="similar to ref|YP_595949.1| hypothetical membrane
                     spanning protein [Streptococcus pyogenes MGAS9429]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122641.1"
                     /db_xref="GI:195977397"
                     /db_xref="GeneID:6760870"
                     /translation="MSSKKRKLVQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLPFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSSLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLH"
     gene            272454..273374
                     /gene="nanA"
                     /locus_tag="Sez_0251"
                     /db_xref="GeneID:6760547"
     CDS             272454..273374
                     /gene="nanA"
                     /locus_tag="Sez_0251"
                     /note="similar to ref|NP_268611.1| putative
                     acylneuraminate lyase [Streptococcus pyogenes M1 GAS];
                     Catalyzes the cleavage of N-acetylneuraminic acid (sialic
                     acid) to form pyruvate and N-acetylmannosamine via a
                     Schiff base intermediate."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase NanA"
                     /protein_id="YP_002122642.1"
                     /db_xref="GI:195977398"
                     /db_xref="GeneID:6760547"
                     /translation="MKILTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAKHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLPELTEADLVICQQAAALIKQTKEQFCY"
     gene            273389..274273
                     /locus_tag="Sez_0252"
                     /db_xref="GeneID:6760868"
     CDS             273389..274273
                     /locus_tag="Sez_0252"
                     /note="Catalysis of ATP + N-acyl-D-mannosamine = ADP +
                     N-acyl-D-mannosamine 6-phosphate."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="YP_002122643.1"
                     /db_xref="GI:195977399"
                     /db_xref="GeneID:6760868"
                     /translation="MKHYLAIDIGGTAIKYGLMTETGDLLEKHEMATEAHKGGPAILD
                     KVKDLVAAYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CEVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDPVSAWNGRRIFEEVKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQIRFASHE
                     NNAGMIGAYYHFKHKEQI"
     gene            274273..275241
                     /locus_tag="Sez_0253"
                     /db_xref="GeneID:6760545"
     CDS             274273..275241
                     /locus_tag="Sez_0253"
                     /note="cephalosporin-C deacetylase; similar to
                     ref|YP_328767.1| acetyl xylan esterase, putative
                     [Streptococcus agalactiae A909]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl xylan esterase 1"
                     /protein_id="YP_002122644.1"
                     /db_xref="GI:195977400"
                     /db_xref="GeneID:6760545"
                     /translation="MIETMSLEEMMSYRGRHEVPKDFDHFWETCIKENQAASYQLDQK
                     DFGLDFADCYELRFKGSNGSTIYAKCVFPKAKQLVPVVFYFHGYQGQSPDWSDQFNYL
                     AAGYAVVSMDVRGQAGYSQDLGQFDGITVKGQVIRGMTSGPEQLFYKDVYLDVYQLID
                     IVSAFARVDDSRLYSYGWSQGGALSLIAAALHPKIAKTVAVYPFLSDFKRVLELGNHS
                     EPYDELFRYFKYHDPFHDTEAEVLGNLAYIDVKNFAHLITCPVVMLTCMEDVICPPST
                     QFAIFNRLATADKCHKLIPDYGHDPMGVKVKDFIFDQLTGSHFTKA"
     gene            complement(275390..276184)
                     /gene="rpiR"
                     /locus_tag="Sez_0254"
                     /db_xref="GeneID:6760866"
     CDS             complement(275390..276184)
                     /gene="rpiR"
                     /locus_tag="Sez_0254"
                     /note="similar to ref|YP_328768.1| phosphosugar-binding
                     transcriptional regulator, RpiR family [Streptococcus
                     agalactiae A909]; Binding to a specific DNA sequence in
                     order to modulate transcription."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid utilization regulator, RpiR family"
                     /protein_id="YP_002122645.1"
                     /db_xref="GI:195977401"
                     /db_xref="GeneID:6760866"
                     /translation="MEAALDSMTSLEKSIAQFFMETDLKVEELTASDMIKRLHVSQAA
                     LTRFAKKCGFTGYREFVFECQKSREAMDQKAPNLQNSNTKKVLMNYRELIEKATELIN
                     EKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVVCEALDDTDSFTWVNSS
                     ITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYRLDEIVHIATARH
                     LNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            276443..277216
                     /locus_tag="Sez_0255"
                     /db_xref="GeneID:6760544"
     CDS             276443..277216
                     /locus_tag="Sez_0255"
                     /note="similar to ref|YP_001127793.1| TatD related DNase
                     [Streptococcus pyogenes str. Manfredo]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative deoxyribonuclease"
                     /protein_id="YP_002122646.1"
                     /db_xref="GI:195977402"
                     /db_xref="GeneID:6760544"
                     /translation="MIEIFDTHTHLNVDHFNGKEDEELALAKELGVSYHNVVGFDQET
                     IDQALALADAYREVYATIGWHPTEAGSYTQAVEDRLIACLKHSKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARYLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            277188..277784
                     /locus_tag="Sez_0256"
                     /db_xref="GeneID:6760864"
     CDS             277188..277784
                     /locus_tag="Sez_0256"
                     /note="similar to ref|YP_279684.1| ribonuclease M5
                     [Streptococcus pyogenes MGAS6180]; Interacting selectively
                     with any nucleic acid."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="YP_002122647.1"
                     /db_xref="GI:195977403"
                     /db_xref="GeneID:6760864"
                     /translation="MQRGCLGLTEKLKIHEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYNGERIRKLIMGAVPTARHAFLHRHEARPRSKS
                     KGRSLGVEHASFEDLQKALSRVTQSFDDESYFDISQTDLIRLGLLLATDSRKRREYLG
                     EGLRIGYSNGKQLLKRLKLFGITLSEVEDVMSSYQAEQ"
     gene            complement(277855..278529)
                     /locus_tag="Sez_0257"
                     /db_xref="GeneID:6760543"
     CDS             complement(277855..278529)
                     /locus_tag="Sez_0257"
                     /note="similar to ref|YP_001201713.1| Thiol-disulfide
                     isomerase and thioredoxin [Streptococcus suis 98HAH33]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transport accessory protein"
                     /protein_id="YP_002122648.1"
                     /db_xref="GI:195977404"
                     /db_xref="GeneID:6760543"
                     /translation="MMKKPNLAYVFPLAPIGIQYLIFWDNSLRFWLPIIGTAIIYGIL
                     LAFKHRYPNVLSDKKGFYIIISFLPICFGVSQLMLNQQASMTAKQATTSTRSVTSTDH
                     SYRTCVQSLTKASLEEINSQSSEDRFYLLYIGRESCPFCRDFCPRLADAIQVTKAKVY
                     YLDTEHKSKALHEFADRFHIHSIPKLLVLRQGRLIKAFDNTNTDDKALISFLEAYQND
                     STLAAS"
     gene            279168..280040
                     /locus_tag="Sez_0258"
                     /db_xref="GeneID:6760862"
     CDS             279168..280040
                     /locus_tag="Sez_0258"
                     /note="similar to ref|YP_601711.1| dimethyladenosine
                     transferase [Streptococcus pyogenes MGAS10750];
                     Specifically dimethylates two adjacent adenosines in the
                     loop of a conserved hairpin near the 3'end of 16S rRNA in
                     the 30S particle. Its inactivation leads to kasugamycin
                     resistance."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyladenosine transferase"
                     /protein_id="YP_002122649.1"
                     /db_xref="GI:195977405"
                     /db_xref="GeneID:6760862"
                     /translation="MRIADYSVTKAILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGL"
     gene            280201..281073
                     /gene="engC"
                     /locus_tag="Sez_0259"
                     /db_xref="GeneID:6760542"
     CDS             280201..281073
                     /gene="engC"
                     /locus_tag="Sez_0259"
                     /note="similar to ref|YP_279686.1| ribosome-associated
                     GTPase [Streptococcus pyogenes MGAS6180]; Unusual
                     circulary permuted GTPase that catalyzes rapid hydrolysis
                     of GTP with a slow catalytic turnover."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-stimulated GTPase EngC"
                     /protein_id="YP_002122650.1"
                     /db_xref="GI:195977406"
                     /db_xref="GeneID:6760542"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNANLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALENGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            281082..281744
                     /gene="cbbE"
                     /locus_tag="Sez_0260"
                     /db_xref="GeneID:6760857"
     CDS             281082..281744
                     /gene="cbbE"
                     /locus_tag="Sez_0260"
                     /EC_number="5.1.3.1"
                     /note="similar to ref|NP_268618.1| ribulose-phosphate
                     3-epimerase [Streptococcus pyogenes M1 GAS];
                     pentose-5-phosphate 3-epimerase; PPE; enzyme that converts
                     D-ribulose 5-phosphate into D-xylulose 5-phosphate in
                     Calvin's reductive pentose phosphate cycle"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="YP_002122651.1"
                     /db_xref="GI:195977407"
                     /db_xref="GeneID:6760857"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTNAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPDCLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAVDLAAQVQTLRAAL
                     NG"
     gene            281737..282369
                     /gene="thiN"
                     /locus_tag="Sez_0261"
                     /db_xref="GeneID:6760541"
     CDS             281737..282369
                     /gene="thiN"
                     /locus_tag="Sez_0261"
                     /note="similar to ref|YP_601714.1| Thiamin
                     pyrophosphokinase [Streptococcus pyogenes MGAS10750];
                     Catalyzes the phosphorylation of thiamine to thiamine
                     pyrophosphate."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphokinase"
                     /protein_id="YP_002122652.1"
                     /db_xref="GI:195977408"
                     /db_xref="GeneID:6760541"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDV
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            282389..283642
                     /gene="rmuC"
                     /locus_tag="Sez_0262"
                     /db_xref="GeneID:6760855"
     CDS             282389..283642
                     /gene="rmuC"
                     /locus_tag="Sez_0262"
                     /note="similar to ref|YP_601715.1| RmuC family protein
                     [Streptococcus pyogenes MGAS10750]; Involved in DNA
                     recombination."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC-like"
                     /protein_id="YP_002122653.1"
                     /db_xref="GI:195977409"
                     /db_xref="GeneID:6760855"
                     /translation="MLVLVLIGLAAYSFVSIKHLQSRLEKALDNNADNLSDQLTYQLD
                     MANKTQLLELSTVMNRQQNELFQQLMDIRDTLHQGLAENRDRSDQRLEVMTQSLSQSV
                     KDLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMRTVAKDV
                     GTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAIKLPGNG
                     QGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIHSKYLNP
                     PETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLSVGFKTL
                     NLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAIVRALAT
                     VEDYQDQSTQSLLHIPLLEEADDED"
     gene            283632..284570
                     /locus_tag="Sez_0263"
                     /db_xref="GeneID:6760540"
     CDS             283632..284570
                     /locus_tag="Sez_0263"
                     /note="similar to ref|NP_268621.1| putative CMP-binding
                     factor [Streptococcus pyogenes M1 GAS]; putative 3'-5'
                     exoribonuclease"
                     /codon_start=1
                     /transl_table=11
                     /product="CMP-binding factor"
                     /protein_id="YP_002122654.1"
                     /db_xref="GI:195977410"
                     /db_xref="GeneID:6760540"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRVGEGEMTNRIFAMDNRSFYKPKY"
     gene            284694..285485
                     /gene="purR"
                     /locus_tag="Sez_0264"
                     /db_xref="GeneID:6760853"
     CDS             284694..285485
                     /gene="purR"
                     /locus_tag="Sez_0264"
                     /note="similar to ref|NP_268622.1| purine operon repressor
                     [Streptococcus pyogenes M1 GAS]; Controls the
                     transcription of the pur operon for purine biosynthetic
                     genes."
                     /codon_start=1
                     /transl_table=11
                     /product="Pur operon repressor"
                     /protein_id="YP_002122655.1"
                     /db_xref="GI:195977411"
                     /db_xref="GeneID:6760853"
                     /translation="MVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKAFE
                     ESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGYIYLSDLLS
                     TPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVRRDLKITEG
                     STVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSLLTEFDSTL
                     VGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            285522..288026
                     /locus_tag="Sez_0265"
                     /db_xref="GeneID:6760539"
     CDS             285522..288026
                     /locus_tag="Sez_0265"
                     /note="similar to ref|NP_268623.1| putative surface
                     exclusion protein [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface exclusion protein"
                     /protein_id="YP_002122656.1"
                     /db_xref="GI:195977412"
                     /db_xref="GeneID:6760539"
                     /translation="MEQENSRTKHVKNTIALTSTIALLGTSVGVSHQVKADDTKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKTTEETLSEQKQQLAETNTNIAETEGEIAKLETAK
                     EEQTADLAKAEELLETYSSMSEEDLAKSIEKHETELEATNTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLAAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKAKADLATVKETVSQQLASDLAANKAALAAKETELQKLQDGTATAQLNVAGSNTLVL
                     PKDYPIEEIKKLAASGYIGTAAYNDYYNKVASTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQAGTAGHYGVGPHDKTIIEASASTVGLRPNDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHRDGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVGSLNEHFVIFP
                     ESDIVDTARFSKTEIPKSGQLIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISHLQSQLDAAQAKSNKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKADLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQAILSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAIDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            288208..288621
                     /gene="rpsL"
                     /locus_tag="Sez_0266"
                     /db_xref="GeneID:6760850"
     CDS             288208..288621
                     /gene="rpsL"
                     /locus_tag="Sez_0266"
                     /note="similar to ref|NP_688761.1| 30S ribosomal protein
                     S12 [Streptococcus agalactiae 2603V/R]; Interacts with and
                     stabilizes bases of the 16S rRNA that are involved in tRNA
                     selection in the A site and with the mRNA backbone.
                     Located at the interface of the 30S and 50S subunits, it
                     traverses the body of the 30S subunit contacting proteins
                     on the other side and probably holding the rRNA structure
                     together. The combined cluster of proteins S8, S12 and S17
                     appears to hold together the shoulder and platform of the
                     30S subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="YP_002122657.1"
                     /db_xref="GI:195977413"
                     /db_xref="GeneID:6760850"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            288642..289112
                     /gene="rpsG"
                     /locus_tag="Sez_0267"
                     /db_xref="GeneID:6760537"
     CDS             288642..289112
                     /gene="rpsG"
                     /locus_tag="Sez_0267"
                     /note="similar to ref|NP_664003.1| 30S ribosomal protein
                     S7 [Streptococcus pyogenes MGAS315]; One of the primary
                     rRNA binding proteins, it binds directly to 16S rRNA where
                     it nucleates assembly of the head domain of the 30S
                     subunit. Is located at the subunit interface close to the
                     decoding center, probably blocks exit of the E-site tRNA."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="YP_002122658.1"
                     /db_xref="GI:195977414"
                     /db_xref="GeneID:6760537"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            289441..291519
                     /gene="fus"
                     /locus_tag="Sez_0268"
                     /db_xref="GeneID:6760846"
     CDS             289441..291519
                     /gene="fus"
                     /locus_tag="Sez_0268"
                     /note="similar to ref|NP_268626.1| elongation factor G
                     [Streptococcus pyogenes M1 GAS]; This protein promotes the
                     GTP-dependent translocation of the nascent protein chain
                     from the A-site to the P-site of the ribosome."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="YP_002122659.1"
                     /db_xref="GI:195977415"
                     /db_xref="GeneID:6760846"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPDEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(291651..291821)
                     /locus_tag="Sez_0269"
                     /db_xref="GeneID:6760536"
     CDS             complement(291651..291821)
                     /locus_tag="Sez_0269"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122660.1"
                     /db_xref="GI:195977416"
                     /db_xref="GeneID:6760536"
                     /translation="MQIPATTLQRNYYITISEKMQTYYPFSKDCFSSNGEPAKSFLGQ
                     LNVSLDVVESAS"
     gene            291899..292909
                     /locus_tag="Sez_0270"
                     /note="GAPDH/NAPlr"
                     /db_xref="GeneID:6760844"
     CDS             291899..292909
                     /locus_tag="Sez_0270"
                     /note="similar to dbj|BAD37145.1|
                     glyceraldehyde-3-phosphate dehydrogenase [Streptococcus
                     gordonii]; Also binds human plasminogen, Nephritis
                     associated plasmin receptor, probable moonlighting dual
                     function non-classical secreted protein."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent glyceraldehyde-3-phosphate
                     dehydrogenase / plasmin(ogen) receptor"
                     /protein_id="YP_002122661.1"
                     /db_xref="GI:195977417"
                     /db_xref="GeneID:6760844"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDQFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKEVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            293453..294307
                     /locus_tag="Sez_0271"
                     /db_xref="GeneID:6760535"
     CDS             293453..294307
                     /locus_tag="Sez_0271"
                     /note="similar to emb|CAA73175.1| acid phosphatase
                     [Streptococcus dysgalactiae subsp. equisimilis]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein E precursor"
                     /protein_id="YP_002122662.1"
                     /db_xref="GI:195977418"
                     /db_xref="GeneID:6760535"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            294516..295712
                     /gene="pgk"
                     /locus_tag="Sez_0272"
                     /db_xref="GeneID:6760841"
     CDS             294516..295712
                     /gene="pgk"
                     /locus_tag="Sez_0272"
                     /note="similar to ref|YP_001034309.1| phosphoglycerate
                     kinase [Streptococcus sanguinis SK36]; Second phase of
                     glycolysis; second step."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="YP_002122663.1"
                     /db_xref="GI:195977419"
                     /db_xref="GeneID:6760841"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRTHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVEAPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLILPVDSKEANAF
                     ADYTEVKVTEGEAVDAGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            295902..296030
                     /locus_tag="Sez_0273"
                     /db_xref="GeneID:6760534"
     CDS             295902..296030
                     /locus_tag="Sez_0273"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122664.1"
                     /db_xref="GI:195977420"
                     /db_xref="GeneID:6760534"
                     /translation="MNESEKGAMWVPFSAFCFRLIVSLLDVKTGFMQVSEPLLGML"
     gene            complement(296183..296317)
                     /locus_tag="Sez_0274"
                     /db_xref="GeneID:6760839"
     CDS             complement(296183..296317)
                     /locus_tag="Sez_0274"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122665.1"
                     /db_xref="GI:195977421"
                     /db_xref="GeneID:6760839"
                     /translation="MPKEIVLSKLSLKLKTAGQGPYLAGPENQKNETKAKQKTQLSQF"
     gene            296280..296657
                     /locus_tag="Sez_0275"
                     /db_xref="GeneID:6760532"
     CDS             296280..296657
                     /locus_tag="Sez_0275"
                     /note="similar to ref|YP_597334.1| hypothetical protein
                     MGAS9429_Spy1603 [Streptococcus pyogenes MGAS9429]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122666.1"
                     /db_xref="GI:195977422"
                     /db_xref="GeneID:6760532"
                     /translation="MRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTL
                     VFVPILTMLTIMFNVAFNNQSGIIGAVAALLIITLSIPNGEAFMYVIARVFETFCGVF
                     IAILVNTDVELIRNKWLNRKFKK"
     gene            296733..297105
                     /gene="glnR"
                     /locus_tag="Sez_0276"
                     /note="HTH-type transcriptional regulator GlnR;
                     unconfirmed disrupted gene, a potential error in the
                     sequence asssembly; transcriptional regulator MerR family"
                     /db_xref="GeneID:6760837"
     gene            297142..298488
                     /gene="glnA"
                     /locus_tag="Sez_0278"
                     /db_xref="GeneID:6760531"
     CDS             297142..298488
                     /gene="glnA"
                     /locus_tag="Sez_0278"
                     /note="similar to ref|YP_597332.1| glutamine synthetase
                     [Streptococcus pyogenes MGAS9429]; Plays an essential role
                     in the metabolism of nitrogen by catalyzing the
                     condensation of glutamate and ammonia to form glutamine,
                     Class I enzymes (GSI) are specific to prokaryotes, and are
                     oligomers of 12 identical subunits. The activity of
                     GSI-type enzyme is controlled by the adenylation of a
                     tyrosine residue. The adenylated enzyme is inactive."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase GlnA"
                     /protein_id="YP_002122667.1"
                     /db_xref="GI:195977423"
                     /db_xref="GeneID:6760531"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKEGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            298721..300379
                     /gene="oppA"
                     /locus_tag="Sez_0279"
                     /db_xref="GeneID:6760833"
     CDS             298721..300379
                     /gene="oppA"
                     /locus_tag="Sez_0279"
                     /note="similar to ref|NP_687990.1| ABC transporter,
                     substrate-binding protein [Streptococcus agalactiae
                     2603V/R]; This protein is a component of the oligopeptide
                     permease, a binding protein-dependent transport system, It
                     binds peptides up to five amino acids long with high
                     affinity. Also required for sporulation and competence."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide-binding protein OppA precursor"
                     /protein_id="YP_002122668.1"
                     /db_xref="GI:195977424"
                     /db_xref="GeneID:6760833"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPEGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKE"
     gene            300546..301460
                     /gene="oppB"
                     /locus_tag="Sez_0280"
                     /db_xref="GeneID:6760530"
     CDS             300546..301460
                     /gene="oppB"
                     /locus_tag="Sez_0280"
                     /note="similar to ref|NP_687185.1| oligopeptide ABC
                     transporter, permease protein [Streptococcus agalactiae
                     2603V/R]; Part of the binding-protein-dependent transport
                     system for oligopeptides; probably responsible for the
                     translocation of the substrate across the membrane. Also
                     required for sporulation and competence."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transport system permease protein
                     OppB"
                     /protein_id="YP_002122669.1"
                     /db_xref="GI:195977425"
                     /db_xref="GeneID:6760530"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLVVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILVTDMIISIADPRVRLG"
     gene            301470..302501
                     /gene="oppC"
                     /locus_tag="Sez_0281"
                     /db_xref="GeneID:6760831"
     CDS             301470..302501
                     /gene="oppC"
                     /locus_tag="Sez_0281"
                     /note="similar to ref|NP_687186.1| oligopeptide ABC
                     transporter, permease protein [Streptococcus agalactiae
                     2603V/R]; Part of the binding-protein-dependent transport
                     system for oligopeptides; probably responsible for the
                     translocation of the substrate across the membrane. Also
                     required for sporulation and competence."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transport system permease protein
                     OppC"
                     /protein_id="YP_002122670.1"
                     /db_xref="GI:195977426"
                     /db_xref="GeneID:6760831"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIKIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASLGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            302514..303560
                     /gene="oppD"
                     /locus_tag="Sez_0282"
                     /db_xref="GeneID:6760529"
     CDS             302514..303560
                     /gene="oppD"
                     /locus_tag="Sez_0282"
                     /note="similar to ref|NP_687187.1| oligopeptide ABC
                     transporter, ATP-binding protein [Streptococcus agalactiae
                     2603V/R]; Part of the binding protein-dependent transport
                     system for oligopeptides. Probably responsible for energy
                     coupling to the transport system. Required for sporulation
                     and competence."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transport ATP-binding protein OppD"
                     /protein_id="YP_002122671.1"
                     /db_xref="GI:195977427"
                     /db_xref="GeneID:6760529"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQAQTASSIIFITHDLGV
                     VAGMADRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            303560..304495
                     /gene="oppF"
                     /locus_tag="Sez_0283"
                     /db_xref="GeneID:6760829"
     CDS             303560..304495
                     /gene="oppF"
                     /locus_tag="Sez_0283"
                     /note="similar to ref|NP_687188.1| oligopeptide ABC
                     transporter, ATP-binding protein [Streptococcus agalactiae
                     2603V/R]; Part of the binding-protein-dependent transport
                     system for oligopeptides. Probably responsible for energy
                     coupling to the transport system."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transport ATP-binding protein OppF"
                     /protein_id="YP_002122672.1"
                     /db_xref="GI:195977428"
                     /db_xref="GeneID:6760829"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQDHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERRRIAEVYDPS
                     QELDGQERQMYEITPGHFVLATQAEADQYRAERGL"
     gene            complement(305117..306799)
                     /gene="ykqC"
                     /locus_tag="Sez_0284"
                     /db_xref="GeneID:6760528"
     CDS             complement(305117..306799)
                     /gene="ykqC"
                     /locus_tag="Sez_0284"
                     /note="similar to ref|ZP_00366343.1| COG0595: Predicted
                     hydrolase of the metallo-beta-lactamase superfamily
                     [Streptococcus pyogenes M49 591]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallo-beta-lactamase family protein,
                     Zn-dependent hydrolase"
                     /protein_id="YP_002122673.1"
                     /db_xref="GI:195977429"
                     /db_xref="GeneID:6760528"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(306801..307031)
                     /locus_tag="Sez_0285"
                     /db_xref="GeneID:6760827"
     CDS             complement(306801..307031)
                     /locus_tag="Sez_0285"
                     /note="similar to ref|YP_603146.1| Putative
                     transcriptional regulator [Streptococcus pyogenes
                     MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator"
                     /protein_id="YP_002122674.1"
                     /db_xref="GI:195977430"
                     /db_xref="GeneID:6760827"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            307317..308015
                     /locus_tag="Sez_0286"
                     /db_xref="GeneID:6760527"
     CDS             307317..308015
                     /locus_tag="Sez_0286"
                     /note="similar to ref|YP_603145.1| Non-proteolytic
                     protein, peptidase family M22 [Streptococcus pyogenes
                     MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative molecular chaperone metal-dependent
                     protease-like"
                     /protein_id="YP_002122675.1"
                     /db_xref="GI:195977431"
                     /db_xref="GeneID:6760527"
                     /translation="MKTLAFDTSNKALSVALLDDDTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLADLVSYDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            308018..308443
                     /gene="rimI"
                     /locus_tag="Sez_0287"
                     /db_xref="GeneID:6760824"
     CDS             308018..308443
                     /gene="rimI"
                     /locus_tag="Sez_0287"
                     /note="similar to ref|YP_597328.1|
                     ribosomal-protein-S18-alanine acetyltransferase
                     [Streptococcus pyogenes MGAS9429]; This Enzyme Acetylates
                     The N-Terminal Alanine Of Ribosomal Protein S18."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-protein-alanine acetyltransferase"
                     /protein_id="YP_002122676.1"
                     /db_xref="GI:195977432"
                     /db_xref="GeneID:6760824"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMRQLDGFEGRIFLEVRASNH
                     RAQQLYLKHGFEVIGQRNNYYHDPIEAALIMRREGKNDR"
     gene            308433..309449
                     /locus_tag="Sez_0288"
                     /db_xref="GeneID:6760526"
     CDS             308433..309449
                     /locus_tag="Sez_0288"
                     /note="similar to ref|ZP_00366339.1| COG0533:
                     Metal-dependent proteases with possible chaperone activity
                     [Streptococcus pyogenes M49 591]; Putative
                     metalloprotease."
                     /codon_start=1
                     /transl_table=11
                     /product="probable O-sialoglycoprotein endopeptidase"
                     /protein_id="YP_002122677.1"
                     /db_xref="GI:195977433"
                     /db_xref="GeneID:6760526"
                     /translation="MTDRYILAVESSCDETSVAVLKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLQSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAKEITDLAVVIPPLRLCGDNAGMIALAAAVEYDKGHVADLDLNAKPSLAFES
                     FHQQ"
     gene            309471..310499
                     /locus_tag="Sez_0289"
                     /db_xref="GeneID:6760821"
     CDS             309471..310499
                     /locus_tag="Sez_0289"
                     /note="similar to ref|ZP_00875785.1| Protein of unknown
                     function DUF218 [Streptococcus suis 89/1591]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122678.1"
                     /db_xref="GI:195977434"
                     /db_xref="GeneID:6760821"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLIFYLLLIVSVYTISSMLNT
                     FYLRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQVYRKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAVQQGIKSEDILVENQSRNTRENILFSKQLIPAGASFCLVTNRYHLFRA
                     LLLAKELALPCRGYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(310897..311232)
                     /gene="rpsN2"
                     /locus_tag="Sez_0290"
                     /db_xref="GeneID:6760525"
     CDS             complement(310897..311232)
                     /gene="rpsN2"
                     /locus_tag="Sez_0290"
                     /note="similar to ref|ZP_00366338.1| COG0199: Ribosomal
                     protein S14 [Streptococcus pyogenes M49 591]; Known to be
                     required for the assembly of 30S particles and may also be
                     responsible for determining the conformation of the 16S
                     rRNA at the A site."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14-2"
                     /protein_id="YP_002122679.1"
                     /db_xref="GI:195977435"
                     /db_xref="GeneID:6760525"
                     /translation="MVEEIQGADNALRLLNIKKEKAMAKKSKIAKYHKQLQLIEQYAD
                     LRRELKAKGDYEALRKLPRDSNPNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQ
                     LPGITKASW"
     gene            complement(311360..312532)
                     /locus_tag="Sez_0291"
                     /db_xref="GeneID:6760818"
     CDS             complement(311360..312532)
                     /locus_tag="Sez_0291"
                     /note="similar to ref|YP_281042.1| NAD(FAD)-utilizing
                     dehydrogenase [Streptococcus pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-utilizing dehydrogenase"
                     /protein_id="YP_002122680.1"
                     /db_xref="GI:195977436"
                     /db_xref="GeneID:6760818"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGHKTLLLDKNRRLGKKLAG
                     TGGGRCNVTNSGSLDELIAGIPGNGRFLYSVFSQFDNHDIIAFFRENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLTSTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKALMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKRLPIPITGKMSLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDINAHTGGFNITAALCSGWVAGSSQS"
     gene            312658..313188
                     /locus_tag="Sez_0292"
                     /db_xref="GeneID:6760524"
     CDS             312658..313188
                     /locus_tag="Sez_0292"
                     /note="similar to ref|YP_001127858.1| putative DNA-binding
                     protein [Streptococcus pyogenes str. Manfredo]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122681.1"
                     /db_xref="GI:195977437"
                     /db_xref="GeneID:6760524"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLIKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            313233..313820
                     /gene="polC"
                     /locus_tag="Sez_0293"
                     /db_xref="GeneID:6760814"
     CDS             313233..313820
                     /gene="polC"
                     /locus_tag="Sez_0293"
                     /note="similar to ref|NP_665412.1| DNA polymerase III
                     subunit epsilon [Streptococcus pyogenes MGAS315]; Required
                     for replicative DNA synthesis. This DNA polymerase also
                     exhibits 3' to 5' exonuclease activity."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III polC-type"
                     /protein_id="YP_002122682.1"
                     /db_xref="GI:195977438"
                     /db_xref="GeneID:6760814"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLAAFKQFVGDMPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAITDNPFAALGGLFD"
     gene            313915..314646
                     /locus_tag="Sez_0294"
                     /db_xref="GeneID:6760522"
     CDS             313915..314646
                     /locus_tag="Sez_0294"
                     /note="similar to ref|YP_599257.1| Transcriptional
                     regulator, MerR family [Streptococcus pyogenes MGAS10270];
                     Transcriptional regulator."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, MerR family"
                     /protein_id="YP_002122683.1"
                     /db_xref="GI:195977439"
                     /db_xref="GeneID:6760522"
                     /translation="MKDMSNIYLTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRR
                     IYTESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKK
                     HQLDTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVML
                     VLLTSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGH
                     TPRTRRLTCPHCHQKSYCLELAKEK"
     gene            314722..315237
                     /locus_tag="Sez_0295"
                     /note="IS861A"
                     /db_xref="GeneID:6760812"
     CDS             314722..315237
                     /locus_tag="Sez_0295"
                     /note="similar to ref|YP_602677.1| Transposase
                     [Streptococcus pyogenes MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS861 orfA"
                     /protein_id="YP_002122684.1"
                     /db_xref="GI:195977440"
                     /db_xref="GeneID:6760812"
                     /translation="MTLSYEDKVQIYELRHIGKSIKCLSEKFSIAESDLKYMIRLIDR
                     YGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTSLDYALPNSSMLSRWIAQYKKN
                     GYTILEKRRGRPPKMGRQPKKTLEQMTELERLQKELDYLRAENAVLKKLREYRLRDEA
                     KLKEQQKSSKN"
     gene            315261..316064
                     /locus_tag="Sez_0296"
                     /note="IS861B"
                     /db_xref="GeneID:6760521"
     CDS             315261..316064
                     /locus_tag="Sez_0296"
                     /note="similar to ref|YP_596865.1| transposase
                     [Streptococcus pyogenes MGAS9429]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS861 orfB"
                     /protein_id="YP_002122685.1"
                     /db_xref="GI:195977441"
                     /db_xref="GeneID:6760521"
                     /translation="MLEILDLSRSTYYYQVKQLAQEDKDMDLKELIQGIYDEHHGNYG
                     YRRIHLELRNRGFIVNHKKVQRLMTVMGLKARIRRKRKYSSYKGEVGKKADNLIKRQF
                     EGSKPYEKCYTDVTEFTLPEGKLYLSPVLDGYNSEIIDFTLSRSPDLKQVQTMLEKAF
                     PADSYNGTILHSDQGWQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFFGILKSE
                     MFYGLETTYQSLNELEQAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
     gene            complement(316121..316420)
                     /locus_tag="Sez_0297"
                     /db_xref="GeneID:6760810"
     CDS             complement(316121..316420)
                     /locus_tag="Sez_0297"
                     /note="similar to ref|YP_281033.1| hypothetical protein
                     M28_Spy1568 [Streptococcus pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122686.1"
                     /db_xref="GI:195977442"
                     /db_xref="GeneID:6760810"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            complement(316498..317649)
                     /gene="intR"
                     /locus_tag="Sez_0298"
                     /db_xref="GeneID:6760520"
     CDS             complement(316498..317649)
                     /gene="intR"
                     /locus_tag="Sez_0298"
                     /note="similar to ref|NP_816189.1| site-specific
                     recombinase, phage integrase family [Enterococcus faecalis
                     V583]; Site-specific tyrosine recombinase, which acts by
                     catalyzing the cutting and rejoining of the recombining
                     DNA molecules. The xerC-xerD complex is essential to
                     convert dimers of the bacterial chromosome into monomers
                     to permit their segregation at cell division. It also
                     contributes to the segregational stability of plasmids."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase xerC-like"
                     /protein_id="YP_002122687.1"
                     /db_xref="GI:195977443"
                     /db_xref="GeneID:6760520"
                     /translation="MAVTRQQNKKWKVDISDGYDAVTGEQKRHRKTDFKTRKEAERYE
                     ADYRINKLHQVTHKDKVSVSYLYSLVKEEDELRGNKRGTIDSQESYYRVYMSKYFKNA
                     DMRAVSVTDIKEYRNWLKSQPSVKGGTLTNSHVNQQMIFVHKMFDVAIANRIRQDNPC
                     NGLRRLSQQHKEMAYYTPEQFKQFDALFEEHEYPFQLLYRVLMFTGIRLGEALALTWK
                     QVNLDEKYIDIRYSAYYRKGKVHIGTVKTTQSNRRIYIHSAFAEELKQWKEKQSQLLN
                     EFTDNPSSLQIFQSTPEVLTGPNVSNFRVVLKKRMPKHLKLIRNHDFRHSHAAFLVSQ
                     GLRNGEGKDYIFFTLMKRLGHSSINTTINVYSHLFPTQQKEIASAFENF"
     gene            complement(317636..317923)
                     /locus_tag="Sez_0299"
                     /db_xref="GeneID:6760806"
     CDS             complement(317636..317923)
                     /locus_tag="Sez_0299"
                     /note="similar to ref|NP_813967.1| hypothetical protein
                     EF0165 [Enterococcus faecalis V583]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122688.1"
                     /db_xref="GI:195977444"
                     /db_xref="GeneID:6760806"
                     /translation="MKESIRGKKMIRIVNKDDVMKLTGFSDSQAKKLIREAKTRLVSE
                     GFSWYKNKRIGRVPIKTIEDILGFELSHKHDIIANVQEDTALEKGVSNGSN"
     gene            complement(317975..319210)
                     /locus_tag="Sez_0300"
                     /db_xref="GeneID:6760519"
     CDS             complement(317975..319210)
                     /locus_tag="Sez_0300"
                     /note="similar to ref|NP_965557.1| hypothetical protein
                     LJ1751 [Lactobacillus johnsonii NCC 533]; Unknown, has
                     some similarity with plasmid/phage replication initiation
                     proteins may function with Sez_0298 which has similarity
                     with plasmid/phage integrase/recombinase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122689.1"
                     /db_xref="GI:195977445"
                     /db_xref="GeneID:6760519"
                     /translation="MRNDILQNINFKNKHLHVGVDELTIVIQPNEETIGEHPDHWNQI
                     ANELSAIIAEKLSLPLLFGGMVKERISPQGYTTSYSFENMPYFLRIAFHEGYLKMGII
                     IKFSASALSLYQQAYENSYRVSIGVCEILKKLDEPYWNMHLSRIDFCADYFNFPLSVN
                     DIYSNLKCKKFEIINYKGNRNHKKMSAIEIDAEAKTVTIGSRKKGSNSFLKIYDKLTE
                     QLENNGRHAQLAQQFQSWVRFEVTFRGQYAKQLTKLILSLPSRDMFQQFIANKILEKY
                     CLINMVTGQPTEYSEALLNFSTIAPPLVATSPRNNQLMQNIHYILKGSGFFPVLEKVK
                     QIWGIPAVTILLKRLLFEYEYNYKPNDDVTNWLKKNALELQILEFEAYLDSVVEIFHI
                     KNAPSSPESAKKPGRKNAE"
     gene            complement(319372..319665)
                     /locus_tag="Sez_0301"
                     /db_xref="GeneID:6760803"
     CDS             complement(319372..319665)
                     /locus_tag="Sez_0301"
                     /note="similar to ref|ZP_01817519.1| hypothetical protein
                     CGSSp3BS71_03347 [Streptococcus pneumoniae SP3-BS71]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122690.1"
                     /db_xref="GI:195977446"
                     /db_xref="GeneID:6760803"
                     /translation="MRINNMAQVEIITVLGISNKEDKKEGWLSCVKTNSPAWKTLLLP
                     FNKEIFSSVFNQQLGIYEVKLNNTAVAFGSKPKFEIAEARLIVSFDEILKAYK"
     gene            complement(320151..320594)
                     /locus_tag="Sez_0302"
                     /db_xref="GeneID:6760518"
     CDS             complement(320151..320594)
                     /locus_tag="Sez_0302"
                     /note="similar to ref|XP_788744.2| PREDICTED: similar to
                     kelch-like ECH-associated protein 1 [Strongylocentrotus
                     purpuratus]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122691.1"
                     /db_xref="GI:195977447"
                     /db_xref="GeneID:6760518"
                     /translation="MDETKKARGGIEIKPDEEYQVVGYSNENHAPIFLGLVVGRDKNT
                     LRVASTTTRLDSFLSEFVSKKNKLITEIASLETELEREVDLKERAINDLDIEIDELKN
                     KLEELQQTYKKRKKLVDAELRKNFYNWIDSNWLLRILYSLYENFS"
     gene            320885..322174
                     /locus_tag="Sez_0303"
                     /db_xref="GeneID:6760801"
     CDS             320885..322174
                     /locus_tag="Sez_0303"
                     /note="similar to ref|ZP_01968479.1| hypothetical protein
                     RUMTOR_02056 [Ruminococcus torques ATCC 27756]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122692.1"
                     /db_xref="GI:195977448"
                     /db_xref="GeneID:6760801"
                     /translation="MQKTIQEFYQEQRTEFSSSLKNYLNYLQSILNWSISFVAESTGI
                     SQNILESWRDNTFISEPSFDELETLSTFASYIEAECKSQMDKDKYKAVYLMHKTRNKF
                     NDELSNLTLKLKESCYIMTKKHPDELTDSHFSEALDEFLYCIKIKYKISSVNVAQELG
                     VSKNTISSWRVGAVPNYENTKKLAEYATKILFNSKNYSDENEFERFTDNFIRFCYHRM
                     EQLDSTKYAQDIIVSLLQGKLKSSKDEPAKIEHLPNSIRKATEFGLFDTIIDGDTVFP
                     GASGLSERAVAKKNKATFVKNFNRLLHLLDKVANNRISDYKELGLCKLSEKDYTLKDE
                     HKQKLQELIRNKLNYRSIDDDGKPLSVQRGLAEYLNVDIAQITNWKNGVDLPTFSNLH
                     KLQKLFGFDRENAFLISEISDFLFLTTLLNLVKQDGE"
     gene            complement(322293..323123)
                     /locus_tag="Sez_0304"
                     /db_xref="GeneID:6760517"
     CDS             complement(322293..323123)
                     /locus_tag="Sez_0304"
                     /note="similar to ref|XP_001431093.1| hypothetical protein
                     GSPATT00033548001 [Paramecium tetraurelia strain d4-2]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122693.1"
                     /db_xref="GI:195977449"
                     /db_xref="GeneID:6760517"
                     /translation="MWYNIFKNLEVSMKTKKIITLALSCLCLTTLLSACASSNTQTTN
                     IPSTASSSKKSTMTIGEYLANDKKPIILFEVKEIDKDTPINSAYVFQNGKVTTYNLSI
                     PLGDLAKLDTNKIIDLLEDKYYKKIQKGYEREIEIWKNDYAYSKENIQEFIGRLEEFK
                     PQLDNFEIKSFPYIINLETDSSGNSTSLEHLKFERIEIKYDPRIDAEGHMDMGIRTSS
                     NIITVHSYAGTYSIYDASFAAFHVPDSSFTKFLITPVKNEITFELDQPTTKLKSITID"
     gene            323629..323766
                     /locus_tag="Sez_0305"
                     /db_xref="GeneID:6760799"
     CDS             323629..323766
                     /locus_tag="Sez_0305"
                     /note="similar to ref|YP_536282.1| hypothetical protein
                     LSL_1395 [Lactobacillus salivarius UCC118]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122694.1"
                     /db_xref="GI:195977450"
                     /db_xref="GeneID:6760799"
                     /translation="MEKVIQNKDTTFSNFMIQACEHVLRDLWDKKKKIPKKVDFFNKI
                     S"
     gene            323797..324507
                     /locus_tag="Sez_0306"
                     /db_xref="GeneID:6760516"
     CDS             323797..324507
                     /locus_tag="Sez_0306"
                     /note="similar to ref|XP_001592791.1| hypothetical protein
                     SS1G_05712 [Sclerotinia sclerotiorum 1980]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122695.1"
                     /db_xref="GI:195977451"
                     /db_xref="GeneID:6760516"
                     /translation="MNNLPQQIYKFAQVFSASRKRDIEKIFSDNEFETKNSRHILNWD
                     FIYRDIANTAKLNKLTSPAMDMGALWTARGVIIEGILYIFMMKQRFEDVINKYEKHHY
                     LTCIARSKNSHLNGKEEGKLSIELFNDLDDDELSESQIEQAKKLLGDHYDFIDEVRVM
                     TFNKKTKEVTVNQVNAFCEFVDAVNITEFDFTKLEVDGRENTPEKPIVALKPGVQKKM
                     EEPKRVSFPAEKKEEIGE"
     gene            324534..325703
                     /locus_tag="Sez_0307"
                     /db_xref="GeneID:6760797"
     CDS             324534..325703
                     /locus_tag="Sez_0307"
                     /note="similar to ref|ZP_00875721.1| Helix-turn-helix
                     motif:Protein of unknown function DUF955 [Streptococcus
                     suis 89/1591]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="YP_002122696.1"
                     /db_xref="GI:195977452"
                     /db_xref="GeneID:6760797"
                     /translation="MMLQISFNGERLKEARLFNKKSITQIAEFLNVSKQMVSKYEKGR
                     ATPSEESLGILEKELQFPRDFFFGNDNFSLSSTGTFFRSRYTATQTEKMPAEINKNYV
                     ALIRDYLGKFIDFPKLDWELSGLDFTPKEYASYIREKWELGDRPIDNLSLLMEEKGFV
                     ISRIDTQSEKVDAFGSAVKVNDNEYYVVVLEGTDYSFYRQQFSLAHELGHWLMHENCK
                     SPQEMGAVEYKQMEDEANEFAAEFLLPKNSFKSSITGREKDIEYYRHLKRVWQVSISM
                     MIMRSKSLDIIDSNEYTNLYKKLSYRGWRKNEPLDSTKLISNPLSLKQSVELLVENRI
                     VMDISADIYRVYNKLLPNFLIEKLCNLDEGYLDELNDRYPNIISLNKERIARGKN"
     gene            325743..326762
                     /locus_tag="Sez_0308"
                     /db_xref="GeneID:6760515"
     CDS             325743..326762
                     /locus_tag="Sez_0308"
                     /note="similar to ref|YP_001308760.1| hypothetical protein
                     Cbei_1630 [Clostridium beijerinckii NCIMB 8052]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122697.1"
                     /db_xref="GI:195977453"
                     /db_xref="GeneID:6760515"
                     /translation="MNGYSKDEVERVLLNIESQRFKENLNNETCLYKNCTHKPIDSHI
                     IQRALLGETLAEDNNVYVWMPQNVARGISQGKEVFFEKTSINRSGVFKGFCGDKGDSH
                     DAKLFRGIETDVKSTSIEEYVFLYSYRSLIYHLWLEKGLTLSQADKVSKMLSNPVITE
                     LSAKINDIPTETRTLLSIDDELPRFENLKKVYEKYIDSEGKIGNFSDGFFVKFLPLDR
                     ITIDFATLGTKVYNSEYPITLGVLPKYKDMPNLFFIVAHKDDETNVLIENLKQITLDN
                     ISQYCWLIQNLPMKWSTNSFLSPKLYDHLTLSGELSQLQNFIASTELLDFNDYQNFNL
                     INVFK"
     gene            327184..327321
                     /locus_tag="Sez_0309"
                     /db_xref="GeneID:6760795"
     CDS             327184..327321
                     /locus_tag="Sez_0309"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122698.1"
                     /db_xref="GI:195977454"
                     /db_xref="GeneID:6760795"
                     /translation="MLVFVMSLCEAVVSVVLGGLTSGAIKKVISLHFYNNNLRINLTL
                     D"
     gene            327391..327834
                     /locus_tag="Sez_0310"
                     /db_xref="GeneID:6760514"
     CDS             327391..327834
                     /locus_tag="Sez_0310"
                     /note="similar to ref|YP_330353.1| hypothetical protein
                     SAK_1753 [Streptococcus agalactiae A909]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122699.1"
                     /db_xref="GI:195977455"
                     /db_xref="GeneID:6760514"
                     /translation="MTTMTTGKQSKTTLAANALKLGLTSAMFAGGAFLALGSAPAVSA
                     STHAGNEQSVTQRLTDQEIYERAQQLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQS
                     EAPQPPAAPQLTGQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            327973..328659
                     /locus_tag="Sez_0311"
                     /db_xref="GeneID:6760793"
     CDS             327973..328659
                     /locus_tag="Sez_0311"
                     /note="similar to ref|NP_734897.1| similar to
                     two-component response regulator [Streptococcus agalactiae
                     NEM316]; Member of the two-component regulatory system,
                     has some similarity with SaeR and PhoP."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="YP_002122700.1"
                     /db_xref="GI:195977456"
                     /db_xref="GeneID:6760793"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYERVWEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKT
                     VWGLGYKLEE"
     gene            328697..329707
                     /locus_tag="Sez_0312"
                     /db_xref="GeneID:6760513"
     CDS             328697..329707
                     /locus_tag="Sez_0312"
                     /note="similar to ref|NP_687428.1| sensor histidine kinase
                     [Streptococcus agalactiae 2603V/R]; Member of the
                     two-component regulatory system, has similarity with SaeS
                     and PhoR."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system histidine kinase"
                     /protein_id="YP_002122701.1"
                     /db_xref="GI:195977457"
                     /db_xref="GeneID:6760513"
                     /translation="MSMLITIAGLIVGLNQMLITIEDISYILVIALIASVAGGIVNMI
                     LLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQMSSELKVSFESLS
                     ESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLNTISRQTNRLNQL
                     VEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQENRSVHIEVAKEVVKI
                     NSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQGQGIKKEDLPLI
                     FKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGSCFSLLLPASPPL
                     GD"
     gene            complement(330079..331809)
                     /gene="fnz"
                     /locus_tag="Sez_0313"
                     /db_xref="GeneID:6760790"
     CDS             complement(330079..331809)
                     /gene="fnz"
                     /locus_tag="Sez_0313"
                     /note="similar to dbj|BAD00710.1| fibronectin-binding
                     protein [Streptococcus equi subsp. zooepidemicus];
                     Unknown, putative cell surface fibronectin-binding
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein Fnz"
                     /protein_id="YP_002122702.1"
                     /db_xref="GI:195977458"
                     /db_xref="GeneID:6760790"
                     /translation="MERRELKTKSFRKVLTTSATCIVLATSFAGGTLRVWADKYYGWN
                     DGTRRDSPFFLYVSPQNDPKRELKDECIVYCFNRDKQWPETWGVNRTFSQVQSEVTFK
                     LPLYEKKKGSDEVFKNNAPRFRGTVKNVTAALVAVLKSGYPTVKSINHLDAEKSRKVT
                     QLAIWYFSDSENDPDTYLQPSEKLTQEEKTAFNSLVEEGKKAGETLSSTGDYTLDIYI
                     TTDKNYAQKQYQNLLGSHVIPKKDDTPNLHGSGPKLNGEIGGKTELPNSIGGESRYPN
                     DEKGEAGPPATPQKPNDPLQGLEGGNSPIVEQNYGSTEGYHGQSGILEETEDTNPPGI
                     ILGGSGNVETHEDTRNPHLMGIGGGLAGESGETTPKPGQTGGHGPIIEITEDTQKGMS
                     GQSGGTIESENTKKPEVLIGGQGQTIETTEDTQKGMSGNSGGTIESEDTKKPEVLIGG
                     QGQIIDFSENTQSGMSGQSGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGG
                     TTIVEDTKKPTPKPKPAPAPIVNDEKPNKGTHLPQTSEFKQLTLSIIGAMSMLLVLCL
                     SLFKRPSKKD"
     gene            332050..333558
                     /locus_tag="Sez_0314"
                     /db_xref="GeneID:6760511"
     CDS             332050..333558
                     /locus_tag="Sez_0314"
                     /note="similar to ref|NP_268584.1| putative regulatory
                     protein - RofA related [Streptococcus pyogenes M1 GAS];
                     RofA-like, probable regulator of adjacent predicted cell
                     surface fibronectin-binding protein."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, RofA-like protein
                     (RALP)"
                     /protein_id="YP_002122703.1"
                     /db_xref="GI:195977459"
                     /db_xref="GeneID:6760511"
                     /translation="MLEEYLEPMINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPYYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRREFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSTLLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILSQ"
     gene            334154..334936
                     /locus_tag="Sez_0315"
                     /db_xref="GeneID:6760788"
     CDS             334154..334936
                     /locus_tag="Sez_0315"
                     /note="similar to ref|YP_001643140.1| Abortive infection
                     protein [Bacillus weihenstephanensis KBAB4]"
                     /codon_start=1
                     /transl_table=11
                     /product="CAAX amino terminal protease family protein"
                     /protein_id="YP_002122704.1"
                     /db_xref="GI:195977460"
                     /db_xref="GeneID:6760788"
                     /translation="MSAYKALLLVTLKIKISRWQYSLANQRTVRIEEESLDIIKRHRA
                     AVLVMLYIIAVYLYRQVSNVIELPPLLNTFLFYGRHLLIFALGICWLYRADYQRDWQQ
                     FSTKWVKNTLWVLVIFAVLYAANILLSSLPLPEGSNAAVLANRYNASEGFETVIFILV
                     VSIIGPFNEELIFRKILIGEGQSGTGMLLARLLGSSLLFGLVHIYSFSELSSIVVYGG
                     LGLLLGLVYVWKKNIYFSTAAHILNNGIGYVFILLELLGVLR"
     gene            complement(335194..335508)
                     /locus_tag="Sez_0316"
                     /db_xref="GeneID:6760510"
     CDS             complement(335194..335508)
                     /locus_tag="Sez_0316"
                     /note="similar to ref|NP_269854.1| putative repressor -
                     phage associated [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="repressor"
                     /protein_id="YP_002122705.1"
                     /db_xref="GI:195977461"
                     /db_xref="GeneID:6760510"
                     /translation="MEQLELANLLGRKSSSSISEWERGKYTPKSGLLSDIAAIFNVSL
                     TDLMEKDLTLENKGVTYQLPQRDLVMISEQLSENNYNKWLDFGQDLLSHQDKEENHKP
                     SK"
     gene            335726..335968
                     /locus_tag="Sez_0317"
                     /db_xref="GeneID:6760786"
     CDS             335726..335968
                     /locus_tag="Sez_0317"
                     /note="similar to ref|YP_060907.1| Transcriptional
                     regulator, Cro/CI family [Streptococcus pyogenes
                     MGAS10394]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Cro/CI family"
                     /protein_id="YP_002122706.1"
                     /db_xref="GI:195977462"
                     /db_xref="GeneID:6760786"
                     /translation="MRGGGKILSKATLKELRIAQKKTQKELSALTGISVRTLARYEKD
                     VQKLRRAKYEKLRGIAEALTISVDDIFLGDDSDFMK"
     gene            336157..336549
                     /locus_tag="Sez_0318"
                     /db_xref="GeneID:6760509"
     CDS             336157..336549
                     /locus_tag="Sez_0318"
                     /note="similar to ref|YP_329140.1| pyridoxamine
                     5'-phosphate oxidase family [Streptococcus agalactiae
                     A909]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122707.1"
                     /db_xref="GI:195977463"
                     /db_xref="GeneID:6760509"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGHAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(336655..338940)
                     /gene="pepX"
                     /locus_tag="Sez_0319"
                     /db_xref="GeneID:6760783"
     CDS             complement(336655..338940)
                     /gene="pepX"
                     /locus_tag="Sez_0319"
                     /note="similar to ref|YP_599253.1| x-prolyl-dipeptidyl
                     aminopeptidase [Streptococcus pyogenes MGAS10270]; Removes
                     N-terminal dipeptides sequentially from polypeptides
                     having unsubstituted N-termini provided that the
                     penultimate residue is proline."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="YP_002122708.1"
                     /db_xref="GI:195977464"
                     /db_xref="GeneID:6760783"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKESFAIFLRKL
                     FFHFQDTDYPLSHMIATKELDLLSFLASDEALTKEVFDLVALQVLGFIPAVDFTDTQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADHIKCEVVYTHGLQDWNVKPRQVYNIFNALPDGLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGEDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILSAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSNLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(338960..339619)
                     /locus_tag="Sez_0320"
                     /db_xref="GeneID:6760508"
     CDS             complement(338960..339619)
                     /locus_tag="Sez_0320"
                     /note="similar to ref|NP_269852.1| putative
                     transcriptional regulatory protein [Streptococcus pyogenes
                     M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, CrP/Fnr family"
                     /protein_id="YP_002122709.1"
                     /db_xref="GI:195977465"
                     /db_xref="GeneID:6760508"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            339788..340987
                     /gene="norA"
                     /locus_tag="Sez_0321"
                     /db_xref="GeneID:6760781"
     CDS             339788..340987
                     /gene="norA"
                     /locus_tag="Sez_0321"
                     /note="similar to ref|YP_281028.1| quinolone resistance
                     norA protein [Streptococcus pyogenes MGAS6180]; Putative
                     quinolone antibiotic resistance protein."
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator superfamily transporter"
                     /protein_id="YP_002122710.1"
                     /db_xref="GI:195977466"
                     /db_xref="GeneID:6760781"
                     /translation="MEDKLFNKHFVGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVLGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYL
                     VRLLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRLIIVLCSVLIAVVVAGAFAFPVTNISLNSEQLAKTKSWTVDSFIEQKALFITL
                     IAFLMGIAYASVLGFQKLYTTEIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFRQLFWLAAVIPVACAVMYFLKTQ
                     AKAIDKG"
     gene            341007..341459
                     /locus_tag="Sez_0322"
                     /db_xref="GeneID:6760507"
     CDS             341007..341459
                     /locus_tag="Sez_0322"
                     /note="similar to ref|NP_688723.1| universal stress
                     protein family [Streptococcus agalactiae 2603V/R]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein family"
                     /protein_id="YP_002122711.1"
                     /db_xref="GI:195977467"
                     /db_xref="GeneID:6760507"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLSYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            341579..342409
                     /gene="gla"
                     /locus_tag="Sez_0323"
                     /db_xref="GeneID:6760777"
     CDS             341579..342409
                     /gene="gla"
                     /locus_tag="Sez_0323"
                     /note="similar to ref|YP_601194.1| Aquaporin / Glycerol
                     uptake facilitator protein [Streptococcus pyogenes
                     MGAS2096]; Mixed channel protein that transports both
                     water and glycerol."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol facilitator-aquaporin Gla"
                     /protein_id="YP_002122712.1"
                     /db_xref="GI:195977468"
                     /db_xref="GeneID:6760777"
                     /translation="MKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLVIAFGYG
                     LGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQLVVVAV
                     YKPYFVQTDNPNNILGSFSTISAVDDGAKSSRKAAYINGFLNEFVGSFVLFFGAMALT
                     KNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSLGGPTGP
                     ALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVVAVAAFKFLYIK"
     gene            342901..343656
                     /locus_tag="Sez_0324"
                     /db_xref="GeneID:6760506"
     CDS             342901..343656
                     /locus_tag="Sez_0324"
                     /note="similar to ref|NP_269848.1| putative C3-degrading
                     proteinase [Streptococcus pyogenes M1 GAS]"
                     /codon_start=1
                     /transl_table=11
                     /product="C3-degrading proteinase"
                     /protein_id="YP_002122713.1"
                     /db_xref="GI:195977469"
                     /db_xref="GeneID:6760506"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRAVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPITLEFNKETGQDLTIAPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVFSDPSQLEIWFVK"
     gene            343653..344603
                     /locus_tag="Sez_0325"
                     /db_xref="GeneID:6760775"
     CDS             343653..344603
                     /locus_tag="Sez_0325"
                     /note="similar to gb|AAT87717.1| Penicillin-binding
                     protein [Streptococcus pyogenes MGAS10394]; Unknown,
                     similar to beta lactamase."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="YP_002122714.1"
                     /db_xref="GI:195977470"
                     /db_xref="GeneID:6760775"
                     /translation="MTLEVIEEVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKEDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGTAAGSAGLFSTLRDL
                     ELFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQLAA
                     IFLTNRTYDKDDRALWIKERRQLRDVIYRAFDTDDTDSPK"
     gene            complement(344824..347211)
                     /gene="pfl"
                     /locus_tag="Sez_0326"
                     /db_xref="GeneID:6760505"
     CDS             complement(344824..347211)
                     /gene="pfl"
                     /locus_tag="Sez_0326"
                     /note="similar to ref|NP_358009.1| Pyruvate formate-lyase
                     [Streptococcus pneumoniae R6]; Glucose metabolism
                     (nonoxidative conversion)."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase"
                     /protein_id="YP_002122715.1"
                     /db_xref="GI:195977471"
                     /db_xref="GeneID:6760505"
                     /translation="MVNLDCKCNRLDLLLDFKEKLMATVKTNADVFEKAWEGFKGTDW
                     KEKASISRFVQANYTPYDGDESFLAGVTERSLHIKKIIEETKAHYEATRFPYDTRPTS
                     IADIPAGFIDKDKELIFGIQNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFT
                     KHVTTVNDGIFRAYTSNIRRARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEK
                     VNDWNAITEIDEESIRLREEINLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNI
                     AFMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFA
                     RTKAYDALYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWT
                     DKLPYAFRRYCMHMSHKHSSIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNI
                     QYFGARVNVLKALLTGLNGGYDDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLT
                     DTYVDALNIIHYMTDKYNYEAVQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVK
                     PIRDEDGYIYDYETIGDYPRWGEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSL
                     LTITSNVAYSKQTGNSPVHRGVYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNS
                     LASLDFSYAADGISLTTQVSPRALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLN
                     DVYDKIMAGEDVIVRISGYCVNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            347357..348460
                     /gene="dinB"
                     /locus_tag="Sez_0327"
                     /db_xref="GeneID:6760773"
     CDS             347357..348460
                     /gene="dinB"
                     /locus_tag="Sez_0327"
                     /note="similar to ref|YP_060898.1| DNA polymerase IV
                     [Streptococcus pyogenes MGAS10394]; Poorly processive,
                     error-prone DNA polymerase involved in untargeted
                     mutagenesis. Copies undamaged DNA at stalled replication
                     forks, which arise in vivo from mismatched or misaligned
                     primer ends. These misaligned primers can be extended by
                     polIV. Exhibits no 3'-5' exonuclease (proofreading)
                     activity. May be involved in translesional synthesis, in
                     conjunction with the beta clamp from polIII."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV DinB"
                     /protein_id="YP_002122716.1"
                     /db_xref="GI:195977472"
                     /db_xref="GeneID:6760773"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKD
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FRRYTDQVEPVSIDEAYLDVTSNKLGIKSALKIARLIQYDIWNSLHLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRIRKSISSERTYAKLLYQEADIKAEI
                     SKNASRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARLIDQTARELFD
                     SLEEHKEGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            complement(348603..349088)
                     /locus_tag="Sez_0328"
                     /db_xref="GeneID:6760504"
     CDS             complement(348603..349088)
                     /locus_tag="Sez_0328"
                     /note="similar to ref|NP_665398.1| hypothetical protein
                     SpyM3_1594 [Streptococcus pyogenes MGAS315]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122717.1"
                     /db_xref="GI:195977473"
                     /db_xref="GeneID:6760504"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGTTVSYV
                     PYIIGIVLYLISIISQLFSQIELVSMIIVLAELALYSFAFYKAKTLNEKDKDKPQSIE
                     E"
     gene            complement(349184..351688)
                     /gene="recD"
                     /locus_tag="Sez_0329"
                     /db_xref="GeneID:6760771"
     CDS             complement(349184..351688)
                     /gene="recD"
                     /locus_tag="Sez_0329"
                     /note="similar to ref|YP_603119.1| Exodeoxyribonuclease V
                     alpha chain [Streptococcus pyogenes MGAS10750]; Exhibits
                     several catalytic activities, including ATP-dependent
                     exonuclease, ATP-stimulated endonuclease, ATP-dependent
                     unwinding and DNA-dependent ATPase activities. strand
                     cleavage occurs 5' to 3' during the unwinding of duplex
                     DNA at Chi sequences, which locally stimulate
                     recombination."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V alpha chain"
                     /protein_id="YP_002122718.1"
                     /db_xref="GI:195977474"
                     /db_xref="GeneID:6760771"
                     /translation="MLSKHSASFREAAIVNVLEPAAVQVFDYLAQKGTVMEHFFTGTV
                     DRIIFDNASNFFKILLLAIEDTDSDFDEADIVITGTMAEIIEGEAYTFWGELTQHPRY
                     GQQLRLSRYQKAKPSSAGLVSYFSSEHFKGIGQKTAEKIIALYGNNPIDDILKNPSRL
                     NEISSLSKANREAFVAKLKANYGTEQVIAALADLGLANRFAFQLFDKYKEEAVHIVKD
                     NPYQLIEDIQGFGFKLADSLAEQLGIESDSPKRFRAALLHCLLEQSIKRGDTYIQARE
                     LLALTISLLEDTRPVECDPAIVANQLTQLIDEGKVMTIGTRVFDSSLYYAEDGIQKHL
                     TRLLQQPLTKEPSQDTIDQEIQAIQEEFAITYDKIQKQAISQALTSKVFILTGGPGTG
                     KTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGRAARRMNELTGLASATIHRHLGLN
                     GDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLTAINSNTQLIIVGDSDQLPSVGPG
                     QVLADLLKVDRIPHITLDKIFRQSEESTIVDLANHIRQGILAPDFCQKKADRSYFEAQ
                     APFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGLAGINSLNQLMQNLLNPLADQTEF
                     LFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDLIPAKYTESKQDEIVIDFDGTEIV
                     YPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQSGRLLQRNLIYTAITRSKSKLIM
                     LGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHTAAASANESNESSLSVKPAPSPQK
                     EQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKKS"
     gene            complement(351812..352411)
                     /gene="lepB"
                     /locus_tag="Sez_0330"
                     /db_xref="GeneID:6760503"
     CDS             complement(351812..352411)
                     /gene="lepB"
                     /locus_tag="Sez_0330"
                     /note="similar to ref|YP_603118.1| Signal peptidase I
                     [Streptococcus pyogenes MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="YP_002122719.1"
                     /db_xref="GI:195977475"
                     /db_xref="GeneID:6760503"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            complement(352436..353311)
                     /gene="rnhC"
                     /locus_tag="Sez_0331"
                     /db_xref="GeneID:6760769"
     CDS             complement(352436..353311)
                     /gene="rnhC"
                     /locus_tag="Sez_0331"
                     /note="similar to ref|YP_001127877.1| ribonuclease HIII
                     [Streptococcus pyogenes str. Manfredo]; Ribonuclease HIII
                     EC:3.1.26 cleaves RNA from DNA-RNA hybrids. It catalyses
                     endonucleolytic cleavage to 5'-phospho-monoesters. Two
                     types of ribonuclease H in Bacillus subtilis, RNase HII
                     (rnhB) and RNase HIII (rnhC), are both known
                     experimentally and are quite similar to each other."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="YP_002122720.1"
                     /db_xref="GI:195977476"
                     /db_xref="GeneID:6760769"
                     /translation="MSSSLIKQLAPYRISNASPYVRLAAKKDGVTLMLYTSGKLVLQG
                     RQAAGLAQELGLQETVADQRPAPSSAQDMPLIGSDEVGNGSYFGGIAVVASFVRPEDH
                     ALLRQLGVDDSKNLSDMSIVQIAPVLKKHIQHRALLLSPKKYNEMVGKGKPYNAVSVK
                     VALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPLTFEEKAEGKYL
                     AVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQVLAAYGMAGLEHCAKL
                     HFANTKKAQALLKNQ"
     gene            353462..353773
                     /locus_tag="Sez_0332"
                     /db_xref="GeneID:6760502"
     CDS             353462..353773
                     /locus_tag="Sez_0332"
                     /note="similar to ref|YP_597299.1| hypothetical cytosolic
                     protein [Streptococcus pyogenes MGAS9429]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122721.1"
                     /db_xref="GI:195977477"
                     /db_xref="GeneID:6760502"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            353770..354318
                     /gene="cvpA"
                     /locus_tag="Sez_0333"
                     /db_xref="GeneID:6760767"
     CDS             353770..354318
                     /gene="cvpA"
                     /locus_tag="Sez_0333"
                     /note="similar to ref|YP_597298.1| CvpA family membrane
                     protein [Streptococcus pyogenes MGAS9429]"
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein CvpA"
                     /protein_id="YP_002122722.1"
                     /db_xref="GI:195977478"
                     /db_xref="GeneID:6760767"
                     /translation="MMLSVLILLLLSWSFYIGYNRGLILQTFYCFGALMSLLFAHHGY
                     KALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAG
                     VLVHLAPVDYFDGFEAKLASGLLAVLVSILFLSMALTILATIPMPFIQGRLHGSLLSR
                     LLVEHCPFISSILRQLWVTAIL"
     gene            354391..356727
                     /gene="mutSB"
                     /locus_tag="Sez_0334"
                     /db_xref="GeneID:6760501"
     CDS             354391..356727
                     /gene="mutSB"
                     /locus_tag="Sez_0334"
                     /note="similar to ref|YP_140176.1| DNA mismatch repair
                     protein [Streptococcus thermophilus LMG 18311]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination inhibitory protein MutS2"
                     /protein_id="YP_002122723.1"
                     /db_xref="GI:195977479"
                     /db_xref="GeneID:6760501"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLEVKKLLQVSAEA
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQAAVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILKQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATN
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDMALAESESILSQLHEKAELKPHEIIEAKHRLKQLVPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            356864..357073
                     /locus_tag="Sez_0335"
                     /db_xref="GeneID:6760765"
     CDS             356864..357073
                     /locus_tag="Sez_0335"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122724.1"
                     /db_xref="GI:195977480"
                     /db_xref="GeneID:6760765"
                     /translation="MSLAGLLLPTRPSLASSLGHEQLLTCLLDTRKNKLLLLAAYPCD
                     KQPKRSLFFNSLAVIPAMQVMLRFF"
     gene            complement(357070..358422)
                     /gene="ykgC"
                     /locus_tag="Sez_0336"
                     /db_xref="GeneID:6760500"
     CDS             complement(357070..358422)
                     /gene="ykgC"
                     /locus_tag="Sez_0336"
                     /note="similar to ref|YP_001198058.1| pyridine
                     nucleotide-disulfide oxidoreductase [Streptococcus suis
                     05ZYH33]"
                     /codon_start=1
                     /transl_table=11
                     /product="probable pyridine nucleotide-disulfide
                     oxidoreductase YkgC"
                     /protein_id="YP_002122725.1"
                     /db_xref="GI:195977481"
                     /db_xref="GeneID:6760500"
                     /translation="MALSNNKKEATMEAYELIVIGFGKAGKTLAAKMAQLGKRVALIE
                     QSPTMYGGTCINIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGV
                     TLYNGKASFVSNKTIQVEAGQEQILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTG
                     ILALTEQPLRLAIIGAGNIGLEFASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDY
                     LEKAGVTFKLSATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTD
                     IKLDDRYAVVVDDYCQTTVEGVYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHK
                     DRGYLPTTVFIEPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVI
                     VNTETNEILGATLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            358568..358882
                     /gene="trxA"
                     /locus_tag="Sez_0337"
                     /db_xref="GeneID:6760763"
     CDS             358568..358882
                     /gene="trxA"
                     /locus_tag="Sez_0337"
                     /note="similar to ref|NP_722180.1| putative thioredoxin
                     [Streptococcus mutans UA159]; Component of the
                     thioredoxin-thioredoxin reductase system. Participates in
                     various redox reactions through the reversible oxidation
                     of its active center dithiol to a disulfide and catalyzes
                     dithiol-disulfide exchange reactions."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="YP_002122726.1"
                     /db_xref="GI:195977482"
                     /db_xref="GeneID:6760763"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            complement(359128..360108)
                     /gene="mlpZ"
                     /locus_tag="Sez_0338"
                     /db_xref="GeneID:6760499"
     CDS             complement(359128..360108)
                     /gene="mlpZ"
                     /locus_tag="Sez_0338"
                     /note="similar to gb|AAQ08496.1| Szp protein
                     [Streptococcus equi subsp. zooepidemicus]; This protein is
                     one of the different antigenic serotypes of protein M.
                     Protein M is closely associated with virulence of the
                     bacterium and can render the organism resistant to
                     phagocytosis."
                     /codon_start=1
                     /transl_table=11
                     /product="M-like protein"
                     /protein_id="YP_002122727.1"
                     /db_xref="GI:195977483"
                     /db_xref="GeneID:6760499"
                     /translation="MNKKSAKRKRSDIIAKLAMTSALTLGVGAAAVMTEQTEVRADVL
                     YQGSLDMRNKEAVEKFVQELKEEVKKKYPDGVTRHKISHVLDGYKNIRAEIETKLSAA
                     EHTRDMYGKQLGLTEKAYQSEKAKKEKLEEELQASQQQNQELNAKLDSEVKEKQELQE
                     QLRKEKEEKDAALAALQEQLNTANQKVQELEATKADLQAKLSEQEQLNAKLKEEVADL
                     TAKLEKLKHCQDTPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEQ
                     PKSMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIAAGTIAIPKRKEED"
     gene            complement(360903..362051)
                     /gene="mutY"
                     /locus_tag="Sez_0339"
                     /db_xref="GeneID:6760761"
     CDS             complement(360903..362051)
                     /gene="mutY"
                     /locus_tag="Sez_0339"
                     /note="similar to ref|YP_140171.1| A/G-specific adenine
                     glycosylase [Streptococcus thermophilus LMG 18311];
                     Adenine glycosylase active on G-A and C-A mispairs."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="YP_002122728.1"
                     /db_xref="GI:195977484"
                     /db_xref="GeneID:6760761"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEIDYDIGDPKNRKIFQAVMEVLIDPDRPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSQGRLLLEKNTQGRLLGGFWSFP
                     LIETDFVSQQLTLFEDKPVVLETMSQTALFEERYGLVPDWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLETYLSKQS"
     gene            362177..362365
                     /locus_tag="Sez_0340"
                     /db_xref="GeneID:6760498"
     CDS             362177..362365
                     /locus_tag="Sez_0340"
                     /note="similar to ref|NP_721760.1| hypothetical protein
                     SMU.1400c [Streptococcus mutans UA159]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122729.1"
                     /db_xref="GI:195977485"
                     /db_xref="GeneID:6760498"
                     /translation="MFLLIILIMVWICQFLQADSTPFIKNNKAVRKNVAVPEWLVRLA
                     DREKVNDSEVLTKALERK"
     gene            363170..363310
                     /locus_tag="Sez_0341"
                     /db_xref="GeneID:6760759"
     CDS             363170..363310
                     /locus_tag="Sez_0341"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122730.1"
                     /db_xref="GI:195977486"
                     /db_xref="GeneID:6760759"
                     /translation="MSFLLVSGFDLATKTYESGDQRALMIKMALLFMRLRQGLRRLFF
                     SI"
     gene            363429..363719
                     /gene="rpsF"
                     /locus_tag="Sez_0342"
                     /db_xref="GeneID:6760497"
     CDS             363429..363719
                     /gene="rpsF"
                     /locus_tag="Sez_0342"
                     /note="similar to ref|NP_269832.1| 30S ribosomal protein
                     S6 [Streptococcus pyogenes M1 GAS]; Binds together with
                     S18 to 16S ribosomal RNA."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6 RpsF"
                     /protein_id="YP_002122731.1"
                     /db_xref="GI:195977487"
                     /db_xref="GeneID:6760497"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTNNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            363738..364226
                     /gene="ssb2"
                     /locus_tag="Sez_0343"
                     /db_xref="GeneID:6760756"
     CDS             363738..364226
                     /gene="ssb2"
                     /locus_tag="Sez_0343"
                     /note="similar to ref|NP_607899.1| single-strand
                     DNA-binding protein [Streptococcus pyogenes MGAS8232];
                     This protein is essential for replication of the
                     chromosome. It is also involved in DNA recombination and
                     repair."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="YP_002122732.1"
                     /db_xref="GI:195977488"
                     /db_xref="GeneID:6760756"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREASSSGSYGGGFNGSPAANSYSAPTQQTPNFGRDESPFGGSNPMDISDDDL
                     PF"
     gene            364385..364624
                     /gene="rpsR"
                     /locus_tag="Sez_0344"
                     /db_xref="GeneID:6760496"
     CDS             364385..364624
                     /gene="rpsR"
                     /locus_tag="Sez_0344"
                     /note="similar to ref|NP_269830.1| 30S ribosomal protein
                     S18 [Streptococcus pyogenes M1 GAS]; Binds as a
                     heterodimer with protein S6 to the central domain of the
                     16S rRNA, where it helps stabilize the platform of the 30S
                     subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="YP_002122733.1"
                     /db_xref="GI:195977489"
                     /db_xref="GeneID:6760496"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            364825..365340
                     /locus_tag="Sez_0345"
                     /note="IS861A"
                     /db_xref="GeneID:6760754"
     CDS             364825..365340
                     /locus_tag="Sez_0345"
                     /note="similar to ref|YP_602677.1| Transposase
                     [Streptococcus pyogenes MGAS10750]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS861 orfA"
                     /protein_id="YP_002122734.1"
                     /db_xref="GI:195977490"
                     /db_xref="GeneID:6760754"
                     /translation="MTLSYEDKVQIYELRHIGKSIKCLSEKFSIAESDLKYMIRLIDR
                     YGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTSLDYALPNSSMLSRWIAQYKKN
                     GYTILEKRRGRPPKMGRQPKKTLEQMTELERLQKELDYLRAENAVLKKLREYRLRDEA
                     KLKEQQKSSKN"
     gene            365364..366167
                     /locus_tag="Sez_0346"
                     /note="IS861B"
                     /db_xref="GeneID:6760495"
     CDS             365364..366167
                     /locus_tag="Sez_0346"
                     /note="similar to ref|YP_596865.1| transposase
                     [Streptococcus pyogenes MGAS9429]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS861 orfB"
                     /protein_id="YP_002122735.1"
                     /db_xref="GI:195977491"
                     /db_xref="GeneID:6760495"
                     /translation="MLEILDLSRSTYYYQVKQLAQEDKDMDLKELIQGIYDEHHGNYG
                     YRRIHLELRNRGFIVNHKKVQRLMTVMGLKARIRRKRKYSSYKGEVGKKADNLIKRQF
                     EGSKPYEKCYTDVTEFTLPEGKLYLSPVLDGYNSEIIDFTLSRSPDLKQVQTMLEKAF
                     PADSYNGTILHSDQGWQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFFGILKSE
                     MFYGLETTYQSLNELEQAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
     gene            complement(366317..366967)
                     /locus_tag="Sez_0347"
                     /db_xref="GeneID:6760752"
     CDS             complement(366317..366967)
                     /locus_tag="Sez_0347"
                     /note="similar to ref|YP_281004.1| hypothetical membrane
                     spanning protein [Streptococcus pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical membrane spanning protein"
                     /protein_id="YP_002122736.1"
                     /db_xref="GI:195977492"
                     /db_xref="GeneID:6760752"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDEDIKTLLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNATVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYAATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMTPQR"
     gene            complement(367144..368088)
                     /gene="corA"
                     /locus_tag="Sez_0348"
                     /db_xref="GeneID:6760493"
     CDS             complement(367144..368088)
                     /gene="corA"
                     /locus_tag="Sez_0348"
                     /note="similar to ref|YP_001127890.1| CorA-like Mg2+
                     transporter protein [Streptococcus pyogenes str.
                     Manfredo]; May play a role in the transport of magnesium."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium and cobalt transport protein CorA"
                     /protein_id="YP_002122737.1"
                     /db_xref="GI:195977493"
                     /db_xref="GeneID:6760493"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIAEQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            368284..371106
                     /gene="uvrA"
                     /locus_tag="Sez_0349"
                     /db_xref="GeneID:6760750"
     CDS             368284..371106
                     /gene="uvrA"
                     /locus_tag="Sez_0349"
                     /note="similar to ref|NP_269827.1| excinuclease ABC
                     subunit A [Streptococcus pyogenes M1 GAS]; The UvrABC
                     repair system catalyzes the recognition and processing of
                     DNA lesions. UvrA is an ATPase and a DNA-binding protein.
                     A damage recognition complex composed of 2 uvrA and 2 uvrB
                     subunits scans DNA for abnormalities. When the presence of
                     a lesion has been verified by uvrB, the uvrA molecules
                     dissociate."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
                     /protein_id="YP_002122738.1"
                     /db_xref="GI:195977494"
                     /db_xref="GeneID:6760750"
                     /translation="MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETSSDYT
                     RNVMRGYMNELTCAACHGYRLNDQALCVRVGGEHGLTIGQVSELSIADHLQLLDGLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPSA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRFIDIKGAAQNNL
                     QNLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNSEKPGRHRSITGIEHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVAAGTPEEVAAVEESYTGQYLKLKL"
     gene            371684..372781
                     /locus_tag="Sez_0350"
                     /db_xref="GeneID:6760492"
     CDS             371684..372781
                     /locus_tag="Sez_0350"
                     /note="similar to ref|YP_060856.1| Xaa-Pro dipeptidase
                     [Streptococcus pyogenes MGAS10394]; The hydrolysis of a
                     peptide bond or bonds within a protein."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP-
                     specific)"
                     /protein_id="YP_002122739.1"
                     /db_xref="GI:195977495"
                     /db_xref="GeneID:6760492"
                     /translation="MSIKEITMSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTG
                     FSGTSATVFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSL
                     AFEDQVSFSFYQHLQATFAGVSLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCD
                     VLDFIKPGQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQG
                     ETLTLDFGCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKASAGMTYREF
                     DAIPRQLIAEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDG
                     KYGVRIEDDLVITETGCQVLTKAPKELIVLT"
     gene            372824..373285
                     /gene="comEB"
                     /locus_tag="Sez_0351"
                     /db_xref="GeneID:6760748"
     CDS             372824..373285
                     /gene="comEB"
                     /locus_tag="Sez_0351"
                     /note="similar to ref|YP_060855.1| ComE operon protein 2
                     [Streptococcus pyogenes MGAS10394]; Catalysis of the
                     reaction: dCMP + H2O = dUMP + NH3, Dispensable for
                     transformability."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase; late competence protein ComEB"
                     /protein_id="YP_002122740.1"
                     /db_xref="GI:195977496"
                     /db_xref="GeneID:6760748"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVGYVQHDVPQIILGGAVEP"
     gene            373379..373936
                     /gene="efp"
                     /locus_tag="Sez_0352"
                     /db_xref="GeneID:6760491"
     CDS             373379..373936
                     /gene="efp"
                     /locus_tag="Sez_0352"
                     /note="similar to ref|NP_269824.1| elongation factor P
                     [Streptococcus pyogenes M1 GAS]; Involved in peptide bond
                     synthesis. Stimulates efficient translation and
                     peptide-bond synthesis on native or reconstituted 70S
                     ribosomes in vitro. Probably functions indirectly by
                     altering the affinity of the ribosome for aminoacyl-tRNA,
                     thus increasing their reactivity as acceptors for peptidyl
                     transferase."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="YP_002122741.1"
                     /db_xref="GI:195977497"
                     /db_xref="GeneID:6760491"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            373979..374368
                     /locus_tag="Sez_0353"
                     /db_xref="GeneID:6760746"
     CDS             373979..374368
                     /locus_tag="Sez_0353"
                     /note="similar to ref|YP_001127895.1| hypothetical protein
                     SpyM50304 [Streptococcus pyogenes str. Manfredo]"
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="YP_002122742.1"
                     /db_xref="GI:195977498"
                     /db_xref="GeneID:6760746"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            374394..374813
                     /gene="nusB"
                     /locus_tag="Sez_0354"
                     /db_xref="GeneID:6760490"
     CDS             374394..374813
                     /gene="nusB"
                     /locus_tag="Sez_0354"
                     /note="similar to ref|NP_688684.1| transcription
                     antitermination protein NusB [Streptococcus agalactiae
                     2603V/R]; Involved in the transcription termination
                     process."
                     /codon_start=1
                     /transl_table=11
                     /product="N utilization substance protein B-like NusB"
                     /protein_id="YP_002122743.1"
                     /db_xref="GI:195977499"
                     /db_xref="GeneID:6760490"
                     /translation="MRERAFQALFTMEMGGDFLLASQFAYDYDKEVADDKQPSELPVF
                     LLNLVNGVMDHKAELDEVIKKNLKAGWSIERLTVVDKTMLRLGLFEMTLFEETPDRVA
                     LNEIIEIAKKYSDDTSAKFINGLLSQFVSDESVAVTD"
     gene            375046..375312
                     /locus_tag="Sez_0355"
                     /db_xref="GeneID:6760744"
     CDS             375046..375312
                     /locus_tag="Sez_0355"
                     /note="similar to ref|YP_001451052.1| hypothetical protein
                     SGO_1783 [Streptococcus gordonii str. Challis substr.
                     CH1]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122744.1"
                     /db_xref="GI:195977500"
                     /db_xref="GeneID:6760744"
                     /translation="MSDTITSSPVAASAAVSELVGVDTSRTHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKLPQLAAKLEKRDLEEATR"
     gene            375324..375683
                     /locus_tag="Sez_0356"
                     /db_xref="GeneID:6760489"
     CDS             375324..375683
                     /locus_tag="Sez_0356"
                     /note="similar to ref|YP_001035341.1| hypothetical protein
                     SSA_1393 [Streptococcus sanguinis SK36]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122745.1"
                     /db_xref="GI:195977501"
                     /db_xref="GeneID:6760489"
                     /translation="MIKEESEEKWLALTRQINELEWLEEDLLSMKRQHEQAVSELQAD
                     CRHLSFALESLLNHMSEDYAGKYAEQEANDHLIRQIDRYVDEHLDHVSTYTMGVRRRL
                     ERDKEELIGERSRLRWE"
     gene            375674..376573
                     /locus_tag="Sez_0357"
                     /db_xref="GeneID:6760742"
     CDS             375674..376573
                     /locus_tag="Sez_0357"
                     /note="similar to ref|YP_001035340.1| hypothetical protein
                     SSA_1392 [Streptococcus sanguinis SK36]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122746.1"
                     /db_xref="GI:195977502"
                     /db_xref="GeneID:6760742"
                     /translation="MGVTYSAAESKALIQAMTNNIQIANEITDRLSSGCDHLIASLDS
                     GELQGAAYTAGRGLFTAIIIPSIKKLQAAIDAIQVELTTYQRADAQIARYGTLDRDHL
                     TELKRLRERQLQVIQAQIDENESFMKQVSSLLTGDYGTLWSDTSTLYHAKNQLEIGIR
                     EVTTKLESLEWFLTQTSDCFRDSLVVLQLAIQGATQLSQVFMSSDGSYSTAGLDMSWV
                     TSLRNQEISPVNASKYTQNHYHNILTRTIKAIKSSSERPLQKSERLVAAYEDYLYFLN
                     KPAFDDQRKNSEKNYNHRVLIFV"
     gene            376570..377013
                     /locus_tag="Sez_0358"
                     /db_xref="GeneID:6760488"
     CDS             376570..377013
                     /locus_tag="Sez_0358"
                     /note="similar to ref|YP_697958.1| bacteriocin
                     [Clostridium perfringens SM101]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122747.1"
                     /db_xref="GI:195977503"
                     /db_xref="GeneID:6760488"
                     /translation="MIVNKMGDDILSVNVNAPYLSQVAGSQLSAAILDNKHFYDLVNT
                     GQPLDLKSRTYHGHNYSVWSRQWESELPGDYAGNYLYGYVGTGFLDASGTYLKTAAGI
                     AQVFSDKDIPKWLKNLSSGHYGDNEGDTQMIQAGIDGYMKRKKSK"
     gene            377271..377516
                     /locus_tag="Sez_0359"
                     /db_xref="GeneID:6760740"
     CDS             377271..377516
                     /locus_tag="Sez_0359"
                     /note="similar to ref|YP_001035338.1| hypothetical protein
                     SSA_1390 [Streptococcus sanguinis SK36]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122748.1"
                     /db_xref="GI:195977504"
                     /db_xref="GeneID:6760740"
                     /translation="MGDIGYRYSITERVIKKYDSNTDNGIIVATGHKGATIDGDGIIV
                     PLKGKRKYSVTEDHDYSITITNLSDKPVAFRAIVADR"
     gene            377723..377929
                     /locus_tag="Sez_0360"
                     /db_xref="GeneID:6760487"
     CDS             377723..377929
                     /locus_tag="Sez_0360"
                     /note="similar to ref|XP_503073.1| hypothetical protein
                     [Yarrowia lipolytica]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122749.1"
                     /db_xref="GI:195977505"
                     /db_xref="GeneID:6760487"
                     /translation="MQVLLGGQAHQAFFWGPIWVYPGGLGFPTSCFGFYFSAPSKGEA
                     RGKPLITEEELLPLEACSWQEGNW"
     gene            complement(377894..378859)
                     /gene="scrR"
                     /locus_tag="Sez_0361"
                     /db_xref="GeneID:6760738"
     CDS             complement(377894..378859)
                     /gene="scrR"
                     /locus_tag="Sez_0361"
                     /note="similar to ref|YP_282907.1| sucrose operon
                     repressor [Streptococcus pyogenes MGAS5005]; Negative
                     regulator of scrB expression."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LacI family ScrR"
                     /protein_id="YP_002122750.1"
                     /db_xref="GI:195977506"
                     /db_xref="GeneID:6760738"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKHGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPNIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKSADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDDLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEILLKKIRQEKTSKDYVLPITLLPGASL"
     gene            complement(378864..380303)
                     /gene="scrB"
                     /locus_tag="Sez_0362"
                     /db_xref="GeneID:6760485"
     CDS             complement(378864..380303)
                     /gene="scrB"
                     /locus_tag="Sez_0362"
                     /note="similar to ref|YP_280995.1| sucrose-6-phosphate
                     hydrolase [Streptococcus pyogenes MGAS6180]; Catalysis of
                     the hydrolysis of terminal non-reducing
                     beta-D-fructofuranoside residues in
                     beta-D-fructofuranosides."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase ScrB"
                     /protein_id="YP_002122751.1"
                     /db_xref="GI:195977507"
                     /db_xref="GeneID:6760485"
                     /translation="MDLPRSIRYRPYQEWNKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQNQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRGRLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDINYPTDKYAYQGALSLVKELRLKNG
                     RLYQAPVPALSKLRDKSQPFQNKKNCSNCYELALTVEAQQTAELLLFADTQQKGLKLT
                     IDTRKGQLTIDRSKAGAQYAQEFRARRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            380582..382465
                     /gene="scrA"
                     /locus_tag="Sez_0363"
                     /db_xref="GeneID:6760736"
     CDS             380582..382465
                     /gene="scrA"
                     /locus_tag="Sez_0363"
                     /note="similar to ref|YP_001127899.1| Gene info PTS
                     system, sucrose-specific IIABC component [Streptococcus
                     pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent
                     sugar phosphotransferase system (PTS), a major
                     carbohydrate active -transport system, catalyzes the
                     phosphorylation of incoming sugar substrates concomitant
                     with their translocation across the cell membrane. This
                     system is involved in sucrose transport."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system sucrose-specific EIIBCA component
                     ScrA"
                     /protein_id="YP_002122752.1"
                     /db_xref="GI:195977508"
                     /db_xref="GeneID:6760736"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPRVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYFVTLLVGLGLAFAIA
                     YIWGFKDKSDQAALATQAKSEPAQKASAAEELLSPVAGELIDLSEVADPVFSSGSMGQ
                     GIAIKPEGRILYSPVDGRVETALETGHAYAIKSDKGAEILLHIGIDTVSMAGDGFEAF
                     VKVGQTVKAGDALGSFDIARIQQAGLDATTMLLVTNSADVHAVQVLAQGKVAVGSPVI
                     LVK"
     gene            382695..385730
                     /gene="endOF2"
                     /locus_tag="Sez_0364"
                     /db_xref="GeneID:6760484"
     CDS             382695..385730
                     /gene="endOF2"
                     /locus_tag="Sez_0364"
                     /note="similar to ref|NP_665373.1| putative
                     sucrose-specific PTS permease, enzyme II [Streptococcus
                     pyogenes MGAS315]; Endohydrolysis of the
                     di-N-acetylchitobiosyl unit in high-mannose glycopeptides
                     and glycoproteins. Complex biantennary glycans are the
                     preferred substrates. Tri- and tetraantennary glycans are
                     not hydrolyzed, and high mannose glycans are very poor
                     substrates."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase F2 precursor"
                     /protein_id="YP_002122753.1"
                     /db_xref="GI:195977509"
                     /db_xref="GeneID:6760484"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLVRVKAEDKLVQTS
                     PSVSAIDDLHYLSENSKKEFKEELSKVEKAQPEKLKEIVSKAQRANQQAKTLAEMKIP
                     EKIPMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSL
                     FWQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDAQKYPNTPEGNKALAKAI
                     VDEYVYKYNLDGLDVDVERDSIPKVNGQESNANIQRSIAVFEEIGKLIGPKGADRSRL
                     FIMDSTYMADKNPLIERGAPYIDLLLVQVYGAQGEKGGFDNANHKAVDTMEERWESYS
                     KYIRPEQYMVGFSFYEEKANSGNLWYDVNVEDDTNPNIGSEIKGTRAERYAKWQPKTG
                     GVKGGIFSYGIDRDGVAHPKKNGPKTPDLDKIVKSDYKVSKALKKVMENDKSYELIDE
                     TDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPAIQSLEGLNKLKKLAKLELIGLS
                     QITKLDSLVLPANAKPTKDTLVSGLETYKNDDRKEEAKAIPQVALTISGLTGLKELNL
                     AGFERETLAGIDAASLTSLEKVDLSKNKLDLAAGTENRQILDTMLATVTKHGGVSEKT
                     FVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSEADYKAYQ
                     EQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETYKVEFFSP
                     TNSTKPVHEAKVVVGEEKTMMVNLAEGATIIGGSADQTNAKKVFDGLLNNDTTTLSTS
                     NKASIIFELKESGLVKHWRFFNDSAKKKEDYIKEAKLEAFVGHLEDSSKVKDSLEKST
                     EWVTVSDYSGEAQEFSQPLNNVGAKYWRITIDNKKSQYGYVSLPELQLIGYQLPAAYP
                     VMATLAAAEELSQQKDKFSQKQLKELEVKVAALKAALDNKMFNADTINASFADVKAYV
                     DKLLADAAGKKTPGKATKEAQLVTTDAKEKAESEKSKAN"
     gene            386100..386984
                     /gene="scrK"
                     /locus_tag="Sez_0365"
                     /db_xref="GeneID:6760733"
     CDS             386100..386984
                     /gene="scrK"
                     /locus_tag="Sez_0365"
                     /note="similar to ref|NP_607886.1| secreted
                     endoglycosidase [Streptococcus pyogenes MGAS8232];
                     Catalysis of the reaction: ATP + D-fructose = ADP +
                     D-fructose 6-phosphate."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="YP_002122754.1"
                     /db_xref="GI:195977510"
                     /db_xref="GeneID:6760733"
                     /translation="MKTLFGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIGRT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLAAAFAIP
                     FYVTTDVNSSAYGEVISRPDIDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYMM
                     LHSDDVANAFLGVCPFHQGCLEGMAAGPSLEARTGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLARVQEAFTRLINGYLPVPDVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            387130..388044
                     /gene="pmi"
                     /locus_tag="Sez_0366"
                     /db_xref="GeneID:6760483"
     CDS             387130..388044
                     /gene="pmi"
                     /locus_tag="Sez_0366"
                     /note="similar to ref|NP_269816.1| putative
                     mannose-6-phosphate isomerase [Streptococcus pyogenes M1
                     GAS]; Involved in the conversion of glucose to
                     GDP-L-fucose."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase Pmi"
                     /protein_id="YP_002122755.1"
                     /db_xref="GI:195977511"
                     /db_xref="GeneID:6760483"
                     /translation="MHDKIWGGTKLREVFGYELPTETTGEYWAISAHPNGVSTVSNGS
                     YQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAYGLAHEGELGK
                     TECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAGDFFYVPSGTM
                     HAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTIGKPENSTPAT
                     LELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSLTIDQAVYELQ
                     KGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            388422..390950
                     /gene="secA"
                     /locus_tag="Sez_0367"
                     /db_xref="GeneID:6760731"
     CDS             388422..390950
                     /gene="secA"
                     /locus_tag="Sez_0367"
                     /note="similar to ref|NP_607882.1| preprotein translocase
                     subunit SecA [Streptococcus pyogenes MGAS8232]; Involved
                     in protein export. Interacts with the secY/secE subunits.
                     SecA has a central role in coupling the hydrolysis of ATP
                     to the transfer of pre-secretory periplasmic and outer
                     membrane proteins across the membrane."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecA subunit"
                     /protein_id="YP_002122756.1"
                     /db_xref="GI:195977512"
                     /db_xref="GeneID:6760731"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGKGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNHDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERATQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            391066..391422
                     /gene="acpS"
                     /locus_tag="Sez_0368"
                     /db_xref="GeneID:6760482"
     CDS             391066..391422
                     /gene="acpS"
                     /locus_tag="Sez_0368"
                     /note="similar to ref|YP_280988.1| 4'-phosphopantetheinyl
                     transferase [Streptococcus pyogenes MGAS6180]; Transfers
                     the 4'-phosphopantetheine moiety from coenzyme A to a Ser
                     of acyl-carrier protein."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-[acyl-carrier-protein] synthase"
                     /protein_id="YP_002122757.1"
                     /db_xref="GI:195977513"
                     /db_xref="GeneID:6760482"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHN
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            391419..392519
                     /gene="alr"
                     /locus_tag="Sez_0369"
                     /db_xref="GeneID:6760729"
     CDS             391419..392519
                     /gene="alr"
                     /locus_tag="Sez_0369"
                     /note="similar to ref|YP_603085.1| alanine racemase
                     [Streptococcus pyogenes MGAS10750]; Provides the D-alanine
                     required for cell wall biosynthesis, catalysis of the
                     reaction: L-alanine = D-alanine."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase Alr"
                     /protein_id="YP_002122758.1"
                     /db_xref="GI:195977514"
                     /db_xref="GeneID:6760729"
                     /translation="MISSLHRPTVARVDLEAIQANIDKIQRHIPKKVKTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADESDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAESEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLLQAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            392789..394204
                     /gene="ispZ"
                     /locus_tag="Sez_0370"
                     /db_xref="GeneID:6760481"
     CDS             392789..394204
                     /gene="ispZ"
                     /locus_tag="Sez_0370"
                     /note="similar to ref|YP_599208.1| Immunogenic secreted
                     protein [Streptococcus pyogenes MGAS10270]; pfam05257,
                     CHAP domain. This domain corresponds to an amidase
                     function, MurNAc-L-Ala amidase. Many of these proteins are
                     involved in cell wall metabolism of bacteria. This domain
                     is found at the N-terminus of the bifunctional Escherichia
                     coli GSP synthetase/GSP amidase, where is functions as a
                     glutathionylspermidine amidase."
                     /codon_start=1
                     /transl_table=11
                     /product="immunogenic secreted protein"
                     /protein_id="YP_002122759.1"
                     /db_xref="GI:195977515"
                     /db_xref="GeneID:6760481"
                     /translation="MRKDKLLRMVMLMTLLAPHLETARVLAEDTGAEVSQISATANEA
                     VVAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGAASSSTGQPTP
                     ASPEVSPQPASEAVAQGAQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAKIMEELDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            394405..398160
                     /locus_tag="Sez_0371"
                     /db_xref="GeneID:6760727"
     CDS             394405..398160
                     /locus_tag="Sez_0371"
                     /note="similar to ref|YP_597265.1| putative
                     Fe3+-siderophore transport protein [Streptococcus pyogenes
                     MGAS9429]; Involoved in iron acquisition."
                     /codon_start=1
                     /transl_table=11
                     /product="putative Fe3+-siderophore transport protein"
                     /protein_id="YP_002122760.1"
                     /db_xref="GI:195977516"
                     /db_xref="GeneID:6760727"
                     /translation="MKSINKCAILALSTLALAQSAQTVRSEATQVSSSLVTTVKLKDN
                     ILLFEEIGPYADKSEGKLYYKNIEKILIDGKEYDKKLEGDYSYDINYQGIKVNAKDIT
                     EGRHQLFIVNKTNGGILVVFDKKGNDVTFVSAKPSDDTTASPQQATAKTEKPAKGTSH
                     DGLATLSFITKLEATEGELLFPEIDRYSSTKQIKELAHQITKVRVNDQDYKDLIYDSV
                     KDKSGYVSDLKGLHLGTTAFKEGDNKIVISSQSFEDVIITVKKSGEQYTFVAAKQKQG
                     QGSQQEAPQGLDFTKLESAIKEAERIIASEVNKEQVKDLSSKLQVIKESYRQIDNEKL
                     LKETYELLMDSIKSYQGTDLAVTDLKAGTYTLTFKANKENTEEASMLQGAFDKKAKLV
                     VKEDGKMEISLLNTALGQFLIDFSIESKGQYPTSVRTQVGERDINNNYIRSEFTLPIE
                     ELDKLHKGAVLVSAMGGQESDLHHYDKYTKLDMTFSATASKGWTGYQAEIDDKEKGIG
                     SERLEKVLVKLGKDLNGDGKMSPEEIAKIEGELRLDHYDLTDISLLKHAKHITELHLE
                     GNQISSIPKETFSQMTNLRFLNLRSNVITTLDKDTFAHNSQLKELYLSSNYMPSLEEG
                     LFRNLAQLDQLDLSKNRISVIRDGVFNGLSRLTSLALAENIITEFSENALASLDNLNF
                     FDVSENQLGSLPSSLNKLTKLSYIVANRNQILDIANIDFSHMPNLLTVDLASNELTKI
                     PQGAFKANKQLSKLNVYNNLLTNISEADFADLKALDLDLKFNCLSGVSDKLRQLMGTN
                     KLNPQKQLANLSAALNHQAITYHQGFSLLDLYYWEQQTLSSTEAEISSIEDYNKRLKA
                     SSSDVIALLNERYADWDIVIQLQKKTSTGQYVTVDERRLNSDPQDELQGSFDLKGAGV
                     YRVRKALITKEFAKKREHIYLTSNDVEVKEDQLAGSGQSKGLDINKLEDGVYYIKASM
                     LKNDLQSESMSHQAIDHRVKLIVNKGVYDLEVTFKGMKVGNLTGYLGELSYFVDGYQR
                     DLTGRPVGKTEKAEVVSYFTDVTGKPLSDAYGSNYPQVLRFRLIDQAKKDGLVPLRVF
                     VPIMDAISKGTGFQTVFMKLDLQSLTKDKAQLPHSEDNQGHGTIGELLQPHTGIIGGH
                     TSPAIPNLTNLLAKKSTAPDNKAKENDKTGTDKLKSLISSHKASKAGAAKASARTAKA
                     KAKSAKPKAAKHSQEQMKADHRGHIIIGLASFIVIAVGLILGRKKLF"
     gene            398413..399294
                     /locus_tag="Sez_0372"
                     /db_xref="GeneID:6760480"
     CDS             398413..399294
                     /locus_tag="Sez_0372"
                     /note="similar to gb|ABI79311.1| heme-binding protein
                     [Streptococcus equi subsp. equi]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="YP_002122761.1"
                     /db_xref="GI:195977517"
                     /db_xref="GeneID:6760480"
                     /translation="MIKRLFKKLIGGLVILLVCLAAIGGKAYADKGELYSCVIRRDYR
                     HPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLADFSGNYQF
                     WVQPGGAGAFQAAAYSVTKVGTDTNGTTKDIAIALPDINTVVRGSMYVEPMGREVVFY
                     LSPSELQEGYSGDMVASFAAGEAKADHAVTAPAKADEKKAPSKPDSKDDKSAPNPPAR
                     PIGQSSTLKKQSSPSKKGQAAGLTTSLDKSKPESSQKPVNNPLSVLVYYIPTALLLSR
                     ALVLFIKKKRKNNEESH"
     gene            399278..400162
                     /locus_tag="Sez_0373"
                     /db_xref="GeneID:6760725"
     CDS             399278..400162
                     /locus_tag="Sez_0373"
                     /note="similar to gb|ABI79312.1| heme-binding lipoprotein
                     [Streptococcus equi subsp. equi]; Binds citrate-dependent
                     iron(III); part of the binding- protein-dependent
                     transport system for uptake of citrate-dependent
                     iron(III)."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome ABC Transporter heme
                     substrate-binding lipoprotein"
                     /protein_id="YP_002122762.1"
                     /db_xref="GI:195977518"
                     /db_xref="GeneID:6760725"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPKAEKKADKERIVATSVAVV
                     DICDRLNLDLIGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEKFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPDLILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVN"
     gene            400164..401186
                     /locus_tag="Sez_0374"
                     /db_xref="GeneID:6760479"
     CDS             400164..401186
                     /locus_tag="Sez_0374"
                     /note="similar to ref|NP_665363.1| putative ferrichrome
                     ABC transporter (permease) [Streptococcus pyogenes
                     MGAS315]; This is one of the proteins involved in the
                     high- affinity transport of ferrichrome."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease protein"
                     /protein_id="YP_002122763.1"
                     /db_xref="GI:195977519"
                     /db_xref="GeneID:6760479"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMILLLMLLFGLMLYAVSVGGL
                     SVSYQRIFSGLFVAYDPEVALIYDLRFPRIVITLLAGAGISTSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDLI"
     gene            401183..401965
                     /locus_tag="Sez_0375"
                     /db_xref="GeneID:6760722"
     CDS             401183..401965
                     /locus_tag="Sez_0375"
                     /note="similar to ref|YP_060837.1| Ferrichrome transport
                     ATP-binding protein [Streptococcus pyogenes MGAS10394];
                     Part of the binding-protein-dependent transport system for
                     Fe(3+)-ferrichrome. Probably responsible for energy
                     coupling to the transport system."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter ATP-binding protein"
                     /protein_id="YP_002122764.1"
                     /db_xref="GI:195977520"
                     /db_xref="GeneID:6760722"
                     /translation="MSHEQGLISVEDLSFTYRDRLILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAKKVAVVHQDNQAVADLLVGDLV
                     AMARQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILTLIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGTIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            402011..403774
                     /locus_tag="Sez_0376"
                     /db_xref="GeneID:6760478"
     CDS             402011..403774
                     /locus_tag="Sez_0376"
                     /note="similar to ref|NP_607874.1| putative ABC
                     transporter (ATP-binding protein) [Streptococcus pyogenes
                     MGAS8232]; Component of a transport system."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_002122765.1"
                     /db_xref="GI:195977521"
                     /db_xref="GeneID:6760478"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTVADVLTVASQGIDSLDTYYSYYLSLAMRTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADKRYEESFVAKAEAFRRATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQG
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVAIDLASKQAINQEILYVSDQSTLLNMSIYENLAIATQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKKAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQAELEANLYG"
     gene            403767..405449
                     /locus_tag="Sez_0377"
                     /db_xref="GeneID:6760720"
     CDS             403767..405449
                     /locus_tag="Sez_0377"
                     /note="similar to ref|YP_597258.1| ABC transporter
                     ATP-binding protein [Streptococcus pyogenes MGAS9429];
                     Component of a transport system."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_002122766.1"
                     /db_xref="GI:195977522"
                     /db_xref="GeneID:6760720"
                     /translation="MVKNDYSTYQLVLRLLAMMKHLLVWIALAVVFAVLGFMLTVSIP
                     TSLAYLGLEVMAGHAIGLKWLYLFIALALLRGLFRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAIIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAIEDLTFTYPKHQETVYHHLSVAFEKKGIIGIQGESGSGKSTLMKVIMKWYSW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACAEGLDTLVTGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            405430..406023
                     /locus_tag="Sez_0378"
                     /db_xref="GeneID:6760477"
     CDS             405430..406023
                     /locus_tag="Sez_0378"
                     /note="similar to ref|NP_607872.1| hypothetical protein
                     spyM18_1861 [Streptococcus pyogenes MGAS8232]; Permease
                     component of an ABC transporter."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="YP_002122767.1"
                     /db_xref="GI:195977523"
                     /db_xref="GeneID:6760477"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGGFFFLTGHFFASMLPALLFGCLADGIA
                     LLGKYQSRLVNLLSYFVFAFVNSGPIILMWLLKDAYIKSLLARGKDMAYVNRVMYDFT
                     AANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            406020..406703
                     /locus_tag="Sez_0379"
                     /db_xref="GeneID:6760717"
     CDS             406020..406703
                     /locus_tag="Sez_0379"
                     /note="similar to ref|NP_607871.1| hypothetical protein
                     spyM18_1860 [Streptococcus pyogenes MGAS8232]; Possibly
                     involved in cobalt transport."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein"
                     /protein_id="YP_002122768.1"
                     /db_xref="GI:195977524"
                     /db_xref="GeneID:6760717"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLGLSVLPLHVLLPVYLFRLLSFAAVAGQLLYPSVLAALIFVKTT
                     TAYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKVIRQSLKIRGIFLDSWAIVRQ
                     PRRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIL
                     ATIIYMVLQ"
     gene            406700..408094
                     /locus_tag="Sez_0380"
                     /db_xref="GeneID:6760476"
     CDS             406700..408094
                     /locus_tag="Sez_0380"
                     /note="similar to ref|YP_001127916.1| ABC transporter
                     ATP-binding protein [Streptococcus pyogenes str.
                     Manfredo]; Part of the ABC transporter complex possibly
                     involved in cobalt import. Responsible for energy coupling
                     to the transport system."
                     /codon_start=1
                     /transl_table=11
                     /product="putative importer ATP-binding protein"
                     /protein_id="YP_002122769.1"
                     /db_xref="GI:195977525"
                     /db_xref="GeneID:6760476"
                     /translation="MIKTKQLQFSYTNRRQTACELRDCQVEAGQFIVLCGQSGSGKST
                     FLKLLNGLIPDYFSGQLQGSLRVLSHQAGQASVEVLSRQVSSVFQNPASQFFYREVKH
                     ELVFPCENQGLEPALILERLDTLAADFDIKDLLEADMLKLSGGQKQRVAIAAAIMQGT
                     AIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAEHRLHYLLDLADHFYYFSAGR
                     LERVLSSKDLLALPDQEREELGLRRCELTAVTKALRAKTVFEHYDPEHALQIKQLEVK
                     AGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLAGIFEAKEAKISYLGVTLSAK
                     DRLSITSLVLQDVGLQLFAETVEKELNLGHHRHQATDDLVNRLGLSQLLDKHPASLSG
                     GEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVNLLKELKQQKKVVIVISHDEE
                     LLDQACDSIYQLGR"
     gene            408472..410487
                     /gene="recG"
                     /locus_tag="Sez_0381"
                     /db_xref="GeneID:6760714"
     CDS             408472..410487
                     /gene="recG"
                     /locus_tag="Sez_0381"
                     /note="similar to ref|NP_722150.1| putative ATP-dependent
                     DNA helicase, RecG [Streptococcus mutans UA159]; Critical
                     role in recombination and DNA repair. Help process
                     Holliday junction intermediates to mature products by
                     catalyzing branch migration. Has a DNA unwinding activity
                     characteristic of a DNA helicase with a 3' to 5' polarity.
                     RecG unwind branched duplex DNA (Y-DNA)."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="YP_002122770.1"
                     /db_xref="GI:195977526"
                     /db_xref="GeneID:6760714"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLD
                     KIVLDQEVAIFGRWDQRKAALTGMKLLMTLEDDLQPVYHVAQGISQPALIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKVAEKRTALSAIADGSVDMIVGTHALIQDTVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHQQLDSVL
                     AWVKTELAKGAQAYVISPLIEESETLDLKNAVALEAELKDYFKASASIALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVATEIVAAKNWQLDPRWAPILANLRVADQFD"
     gene            complement(410608..411531)
                     /gene="ansA"
                     /locus_tag="Sez_0382"
                     /db_xref="GeneID:6760475"
     CDS             complement(410608..411531)
                     /gene="ansA"
                     /locus_tag="Sez_0382"
                     /note="similar to ref|NP_269796.1| putative L-asparaginase
                     [Streptococcus pyogenes M1 GAS]; Catalysis of the
                     reaction: L-asparagine + H2O = L-aspartate + NH3."
                     /codon_start=1
                     /transl_table=11
                     /product="probable L-asparaginase"
                     /protein_id="YP_002122771.1"
                     /db_xref="GI:195977527"
                     /db_xref="GeneID:6760475"
                     /translation="MQADEAGKVSPNQNNPMTQVGLSLEHIHLTVVDFLNLPSPHITP
                     HHMLKMYHYIQQRVSQFDAVVITHGTDTLEETAYFLDTMVLPIELPIVITGAMRSANE
                     IGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTHTTNVSTFQTPTHGP
                     LGIVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSILSLLTPDRIQGLVI
                     EALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYCGGGASLKRAGVMFV
                     KELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            411645..413033
                     /locus_tag="Sez_0383"
                     /db_xref="GeneID:6760711"
     CDS             411645..413033
                     /locus_tag="Sez_0383"
                     /note="similar to ref|ZP_00365596.1| COG0561: Predicted
                     hydrolases of the HAD superfamily [Streptococcus pyogenes
                     M49 591]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase (HAD superfamily)"
                     /protein_id="YP_002122772.1"
                     /db_xref="GI:195977528"
                     /db_xref="GeneID:6760711"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILSRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQELYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(413320..413748)
                     /locus_tag="Sez_0384"
                     /db_xref="GeneID:6760474"
     CDS             complement(413320..413748)
                     /locus_tag="Sez_0384"
                     /note="similar to ref|YP_280968.1| universal stress
                     protein family [Streptococcus pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="YP_002122773.1"
                     /db_xref="GI:195977529"
                     /db_xref="GeneID:6760474"
                     /translation="MVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDTRALQSVAT
                     FDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEKIDLI
                     MVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            414047..415260
                     /gene="alaT"
                     /locus_tag="Sez_0385"
                     /note="aspartate aminotransferase; unconfirmed disrupted
                     gene, a potential error in the sequence asssembly"
                     /db_xref="GeneID:6760709"
     gene            415432..416214
                     /gene="codY"
                     /locus_tag="Sez_0387"
                     /db_xref="GeneID:6760473"
     CDS             415432..416214
                     /gene="codY"
                     /locus_tag="Sez_0387"
                     /note="similar to ref|YP_060823.1| transcriptional
                     repressor CodY [Streptococcus pyogenes MGAS10394];
                     DNA-binding protein that represses the expression of many
                     genes that are induced as cells make the transition from
                     rapid exponential growth to stationary phase. It is a
                     GTP-binding protein that senses the intracellular GTP
                     concentration as an indicator of nutritional limitations.
                     At low GTP concentration it no longer binds GTP and stop
                     to act as a transcriptional repressor (By similarity)."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing transcriptional pleiotropic
                     repressor codY"
                     /protein_id="YP_002122774.1"
                     /db_xref="GI:195977530"
                     /db_xref="GeneID:6760473"
                     /translation="MPNLLQKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PVESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            416842..417399
                     /locus_tag="Sez_0388"
                     /db_xref="GeneID:6760707"
     CDS             416842..417399
                     /locus_tag="Sez_0388"
                     /note="similar to ref|YP_001034560.1| Isochorismitase
                     family protein, putative [Streptococcus sanguinis SK36];
                     Catalysis of the reaction: nicotinamide + H2O = nicotinate
                     + NH3."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrazinamidase/nicotinamidase"
                     /protein_id="YP_002122775.1"
                     /db_xref="GI:195977531"
                     /db_xref="GeneID:6760707"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYSKYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     SRENHQWALNHCRTVLGAKLLDRLS"
     gene            417881..418183
                     /gene="gatC"
                     /locus_tag="Sez_0389"
                     /db_xref="GeneID:6760471"
     CDS             417881..418183
                     /gene="gatC"
                     /locus_tag="Sez_0389"
                     /note="similar to ref|YP_599185.2| aspartyl/glutamyl-tRNA
                     amidotransferase subunit C [Streptococcus pyogenes
                     MGAS10270]; Allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in
                     organisms which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases. The reaction takes place in
                     the presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA(Gln) amidotransferase subunit C
                     GatC"
                     /protein_id="YP_002122776.1"
                     /db_xref="GI:195977532"
                     /db_xref="GeneID:6760471"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGIAITTTMADKKNIMRADIAEAGVDRKFLFQNVPEKENHFIKVPAILDDGGDA"
     gene            418183..419649
                     /gene="gatA"
                     /locus_tag="Sez_0390"
                     /db_xref="GeneID:6760705"
     CDS             418183..419649
                     /gene="gatA"
                     /locus_tag="Sez_0390"
                     /note="similar to ref|NP_607859.1| aspartyl/glutamyl-tRNA
                     amidotransferase subunit A [Streptococcus pyogenes
                     MGAS8232]; Furnishes a means for formation of correctly
                     charged Gln-tRNA(Gln) through the transamidation of
                     misacylated Glu- tRNA(Gln) in organisms which lack
                     glutaminyl-tRNA synthetase. The reaction takes place in
                     the presence of glutamine and ATP through an activated
                     gamma-phospho-Glu-tRNA(Gln)."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA(Gln) amidotransferase subunit A
                     GatC"
                     /protein_id="YP_002122777.1"
                     /db_xref="GI:195977533"
                     /db_xref="GeneID:6760705"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIAEEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIIIGKTNMDEFAMGGSTETSYFKKTKNAWDRSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLTVIAGSDRKDSTSAPVQIADYTSKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQAAAAFEATTDYHKQQPMIFGGDS"
     gene            419649..421088
                     /gene="gatB"
                     /locus_tag="Sez_0391"
                     /db_xref="GeneID:6760470"
     CDS             419649..421088
                     /gene="gatB"
                     /locus_tag="Sez_0391"
                     /note="similar to ref|NP_269788.1| aspartyl/glutamyl-tRNA
                     amidotransferase subunit B [Streptococcus pyogenes M1
                     GAS]; Allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in
                     organisms which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases. The reaction takes place in
                     the presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase
                     subunit B GatB"
                     /protein_id="YP_002122778.1"
                     /db_xref="GI:195977534"
                     /db_xref="GeneID:6760470"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPAERRVSYIKDLGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIDQLALTPDSLVEMIAIIADGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            421317..422261
                     /locus_tag="Sez_0392"
                     /db_xref="GeneID:6760703"
     CDS             421317..422261
                     /locus_tag="Sez_0392"
                     /note="similar to ref|YP_820933.1| permease of the
                     drug/metabolite transporter (DMT) superfamily
                     [Streptococcus thermophilus LMD-9]"
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite transporter (DMT) superfamily
                     protein"
                     /protein_id="YP_002122779.1"
                     /db_xref="GI:195977535"
                     /db_xref="GeneID:6760703"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHEVGINALTSLRLI
                     ISGLVLSSMAYMRQRDAVIRLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVFFAIILMKETFHPIDL
                     LGMALILIAVLVISLRDLLLAQRKKQLALKAKRLPSSD"
     gene            422309..422551
                     /locus_tag="Sez_0393"
                     /db_xref="GeneID:6760469"
     CDS             422309..422551
                     /locus_tag="Sez_0393"
                     /note="similar to ref|YP_060816.1| Hypothetical membrane
                     spanning protein [Streptococcus pyogenes MGAS10394]"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_002122780.1"
                     /db_xref="GI:195977536"
                     /db_xref="GeneID:6760469"
                     /translation="MMIWSLIVGAIIGMIAGRITEKSHSMGCFTMTAAGLIGSAVGQK
                     LFGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            422760..423767
                     /gene="sfs"
                     /locus_tag="Sez_0394"
                     /db_xref="GeneID:6760701"
     CDS             422760..423767
                     /gene="sfs"
                     /locus_tag="Sez_0394"
                     /note="similar to gb|AAD29424.1|AF136451_1
                     fibronectin-binding protein SFS [Streptococcus equi];
                     Probable secreted adhesin, however lacks canonical
                     secretion signal sequence. Has some similarity with the
                     eukaryotic ECM protein, repetin."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein Sfs-like"
                     /protein_id="YP_002122781.1"
                     /db_xref="GI:195977537"
                     /db_xref="GeneID:6760701"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQASPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPSTP
                     NLEGNNRKNPLKGLDGENKPKEDLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYE
                     DGYGGKKHKGDYPKRFDESSPKEYNDYSQGYNDNYGNGYLDGLADRDGKRGYGYSYNP
                     D"
     gene            424032..424298
                     /locus_tag="Sez_0395"
                     /db_xref="GeneID:6760468"
     CDS             424032..424298
                     /locus_tag="Sez_0395"
                     /note="similar to gb|AAK99021.1| Conserved hypothetical
                     protein [Streptococcus pneumoniae R6]; Unknown, ACT domain
                     containing transcriptional regulators, related to gcvR of
                     E.coli."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122782.1"
                     /db_xref="GI:195977538"
                     /db_xref="GeneID:6760468"
                     /translation="MKVIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            424313..425650
                     /locus_tag="Sez_0396"
                     /db_xref="GeneID:6760698"
     CDS             424313..425650
                     /locus_tag="Sez_0396"
                     /note="similar to ref|YP_001449706.1| glycerol-3-phosphate
                     dehydrogenase (NAD(P)+) [Streptococcus gordonii str.
                     Challis substr. CH1]; De novo phospholipid biosynthesis;
                     glycerol-3 phosphate formation."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase (NAD(P)+)"
                     /protein_id="YP_002122783.1"
                     /db_xref="GI:195977539"
                     /db_xref="GeneID:6760698"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCVDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLPLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTKKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEMGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEMVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            425767..426432
                     /locus_tag="Sez_0397"
                     /db_xref="GeneID:6760467"
     CDS             425767..426432
                     /locus_tag="Sez_0397"
                     /note="similar to ref|NP_607855.1| putative
                     phosphoglycerate mutase [Streptococcus pyogenes MGAS8232]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase family"
                     /protein_id="YP_002122784.1"
                     /db_xref="GI:195977540"
                     /db_xref="GeneID:6760467"
                     /translation="MFNTIGRAQGWSDTPLTKAGEEGIRELGLGLKAAGIPFKAAFSS
                     DSGRTMQTMEIILRESENEFLPYTRDKRIREWCFGSLDGAYDSELFLGVLPRTRAFEN
                     RDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIALAIENAGGGNAIVVS
                     HGMTIGTFMWLIDPDREKQYIDNGSVTVVEFENGQFTIKTIGDMSYRYCGREIIESIR
                     DEE"
     gene            426422..427165
                     /locus_tag="Sez_0398"
                     /db_xref="GeneID:6760695"
     CDS             426422..427165
                     /locus_tag="Sez_0398"
                     /note="similar to ref|NP_607854.1| putative
                     D,D-carboxypeptidase [Streptococcus pyogenes MGAS8232];
                     Vancomycin-inducible, penicillin-resistant, DD-
                     carboxypeptidase that hydrolyzes depsipeptide- and
                     D-alanyl-D- alanine-containing peptidoglycan precursors.
                     Insensitive to beta- lactams."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="YP_002122785.1"
                     /db_xref="GI:195977541"
                     /db_xref="GeneID:6760695"
                     /translation="MKNNAIRVLLQALVVLLFLSGIYLFIKPEQQAVGQKANQTAPAP
                     KAVKQAKKTTDLPKVSATDWQLVLVNHDHPQEERSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASAQYITAHSLSLEEYLTRLKEKK"
     gene            427213..427698
                     /locus_tag="Sez_0399"
                     /db_xref="GeneID:6760466"
     CDS             427213..427698
                     /locus_tag="Sez_0399"
                     /note="similar to ref|NP_607853.1| putative
                     N-acetyl-muramidase [Streptococcus pyogenes MGAS8232]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-muramidase"
                     /protein_id="YP_002122786.1"
                     /db_xref="GI:195977542"
                     /db_xref="GeneID:6760466"
                     /translation="MVALIGPLLFNAKGTSASQEMSVPYTERQFIQLVAKEVKPLAKN
                     YGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQASISLKKQAASKHKTAYAI
                     YRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGIKNLLKVCRPIAILMIRAMPKGLC
                     S"
     gene            428181..429215
                     /gene="hrcA"
                     /locus_tag="Sez_0400"
                     /db_xref="GeneID:6760693"
     CDS             428181..429215
                     /gene="hrcA"
                     /locus_tag="Sez_0400"
                     /note="similar to ref|ZP_00780723.1| heat-inducible
                     transcription repressor HrcA [Streptococcus agalactiae
                     18RS21]; Negative regulator of class I heat shock genes
                     (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock
                     induction of these operons."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="YP_002122787.1"
                     /db_xref="GI:195977543"
                     /db_xref="GeneID:6760693"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDFYQLVKAFDFEAFKLE
                     DVLLRASQMLSDMTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            429260..429829
                     /gene="grpE"
                     /locus_tag="Sez_0401"
                     /db_xref="GeneID:6760465"
     CDS             429260..429829
                     /gene="grpE"
                     /locus_tag="Sez_0401"
                     /note="similar to ref|NP_720560.1| heat shock protein GrpE
                     (HSP-70 cofactor) [Streptococcus mutans UA159];
                     Participates actively in the response to hyperosmotic and
                     heat shock by preventing the aggregation of
                     stress-denatured proteins, in association with dnaK and
                     grpE. It is the nucleotide exchange factor for dnaK and
                     may function as a thermosensor. Unfolded proteins bind
                     initially to dnaJ; upon interaction with the dnaJ-bound
                     protein, dnaK hydrolyzes its bound ATP, resulting in the
                     formation of a stable complex. GrpE releases ADP from
                     dnaK; ATP binding to dnaK triggers the release of the
                     substrate protein, thus completing the reaction cycle.
                     Several rounds of ATP- dependent interactions between
                     dnaJ, dnaK and grpE are required for fully efficient
                     folding."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein GrpE"
                     /protein_id="YP_002122788.1"
                     /db_xref="GI:195977544"
                     /db_xref="GeneID:6760465"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSADTVADEAAKE
                     LSELEQALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVDGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            430217..432070
                     /gene="dnaK"
                     /locus_tag="Sez_0402"
                     /db_xref="GeneID:6760691"
     CDS             430217..432070
                     /gene="dnaK"
                     /locus_tag="Sez_0402"
                     /note="similar to ref|YP_599175.1| Chaperone protein dnaK
                     [Streptococcus pyogenes MGAS10270]; Acts as a chaperone."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein DnaK"
                     /protein_id="YP_002122789.1"
                     /db_xref="GI:195977545"
                     /db_xref="GeneID:6760691"
                     /translation="MYKRGKNIMSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTT
                     PSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMIL
                     QYLKGYAEDYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALA
                     YGLDKTDKEEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFL
                     VAEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEM
                     SLSRAKFDDLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAE
                     TGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDR
                     NTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQI
                     EVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRK
                     EEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQAALDELKKAQESGDLDDMKAKL
                     EALNEKAQALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            432227..433363
                     /gene="dnaJ"
                     /locus_tag="Sez_0403"
                     /db_xref="GeneID:6760464"
     CDS             432227..433363
                     /gene="dnaJ"
                     /locus_tag="Sez_0403"
                     /note="similar to ref|YP_603051.1| Chaperone protein dnaJ
                     [Streptococcus pyogenes MGAS10750]; Participates actively
                     in the response to hyperosmotic and heat shock by
                     preventing the aggregation of stress-denatured proteins
                     and by disaggregating proteins, also in an autonomous,
                     dnaK-independent fashion. Unfolded proteins bind initially
                     to dnaJ; upon interaction with the dnaJ-bound protein,
                     dnaK hydrolyzes its bound ATP, resulting in the formation
                     of a stable complex. GrpE releases ADP from dnaK; ATP
                     binding to dnaK triggers the release of the substrate
                     protein, thus completing the reaction cycle. Several
                     rounds of ATP-dependent interactions between dnaJ, dnaK
                     and grpE are required for fully efficient folding. Also
                     involved, together with dnaK and grpE, in the DNA
                     replication of plasmids through activation of initiation
                     proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein DnaJ"
                     /protein_id="YP_002122790.1"
                     /db_xref="GI:195977546"
                     /db_xref="GeneID:6760464"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDICHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            433621..434481
                     /locus_tag="Sez_0404"
                     /db_xref="GeneID:6760688"
     CDS             433621..434481
                     /locus_tag="Sez_0404"
                     /note="similar to ref|NP_607848.1| enoyl-CoA hydratase
                     [Streptococcus pyogenes MGAS8232]; Possibly oxidizes fatty
                     acids."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-2,cis-3-decenoyl-ACP isomerase"
                     /protein_id="YP_002122791.1"
                     /db_xref="GI:195977547"
                     /db_xref="GeneID:6760688"
                     /translation="MIVKLFGHKIICSSNKLSEKRSDMTFQNIIFELEEDLAILTLNR
                     PEVSNGFNIPACQEILEAIQLVKDNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDV
                     QSLVKIAELVQDISFAIKQLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAF
                     VNVGLAPDAGGLFLLTRAVGLNRATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTC
                     SQLLKRLRRGSSNSYAGMKSLVWQSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYG
                     DRRRPNFQGK"
     gene            434561..434995
                     /locus_tag="Sez_0405"
                     /db_xref="GeneID:6760463"
     CDS             434561..434995
                     /locus_tag="Sez_0405"
                     /note="similar to ref|YP_280949.1| transcriptional
                     regulator, MarR family [Streptococcus pyogenes MGAS6180];
                     Transcriptional repressor."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator of fatty acid
                     biosynthesis FabT"
                     /protein_id="YP_002122792.1"
                     /db_xref="GI:195977548"
                     /db_xref="GeneID:6760463"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            434995..435969
                     /locus_tag="Sez_0406"
                     /db_xref="GeneID:6760685"
     CDS             434995..435969
                     /locus_tag="Sez_0406"
                     /note="similar to ref|YP_060806.1| 3-oxoacyl-(acyl carrier
                     protein) synthase III [Streptococcus pyogenes MGAS10394];
                     Catalyzes the condensation reaction of fatty acid
                     synthesis by the addition to an acyl acceptor of two
                     carbons from malonyl-ACP. Catalyzes the first condensation
                     reaction which initiates fatty acid synthesis and may
                     therefore play a role in governing the total rate of fatty
                     acid production. Possesses both acetoacetyl-ACP synthase
                     and acetyl transacylase activities. Its substrate
                     specificity determines the biosynthesis of branched- chain
                     and/or straight-chain of fatty acids."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III"
                     /protein_id="YP_002122793.1"
                     /db_xref="GI:195977549"
                     /db_xref="GeneID:6760685"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGARSQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSIAAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            436027..436251
                     /gene="acpP"
                     /locus_tag="Sez_0407"
                     /db_xref="GeneID:6760461"
     CDS             436027..436251
                     /gene="acpP"
                     /locus_tag="Sez_0407"
                     /note="similar to ref|NP_687379.1| acyl carrier protein
                     [Streptococcus agalactiae 2603V/R]; Carrier of the growing
                     fatty acid chain in fatty acid biosynthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein AcpP"
                     /protein_id="YP_002122794.1"
                     /db_xref="GI:195977550"
                     /db_xref="GeneID:6760461"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            436446..437432
                     /locus_tag="Sez_0408"
                     /db_xref="GeneID:6760683"
     CDS             436446..437432
                     /locus_tag="Sez_0408"
                     /note="similar to ref|NP_269774.1| putative
                     trans-2-enoyl-ACP reductase II [Streptococcus pyogenes M1
                     GAS]; Catalysis of the reaction: acyl-[acyl-carrier
                     protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier
                     protein] + NADH + H+."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase (FMN)"
                     /protein_id="YP_002122795.1"
                     /db_xref="GI:195977551"
                     /db_xref="GeneID:6760683"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSVPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVVN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            437445..438365
                     /gene="fabD"
                     /locus_tag="Sez_0409"
                     /db_xref="GeneID:6760460"
     CDS             437445..438365
                     /gene="fabD"
                     /locus_tag="Sez_0409"
                     /note="similar to ref|NP_269773.1| acyl-carrier-protein
                     S-malonyltransferase [Streptococcus pyogenes M1 GAS];
                     Fatty acid biosynthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl CoA-acyl carrier protein transacylase
                     FabD"
                     /protein_id="YP_002122796.1"
                     /db_xref="GI:195977552"
                     /db_xref="GeneID:6760460"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQHAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGA
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIDVMKANGVNQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            438382..439116
                     /gene="fabG"
                     /locus_tag="Sez_0410"
                     /db_xref="GeneID:6760679"
     CDS             438382..439116
                     /gene="fabG"
                     /locus_tag="Sez_0410"
                     /note="similar to ref|NP_607842.1|
                     3-ketoacyl-(acyl-carrier-protein) reductase [Streptococcus
                     pyogenes MGAS8232]; Fatty acid biosynthesis pathway; first
                     reduction step."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase FabG"
                     /protein_id="YP_002122797.1"
                     /db_xref="GI:195977553"
                     /db_xref="GeneID:6760679"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKVNLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILSQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            439132..440364
                     /gene="fabF"
                     /locus_tag="Sez_0411"
                     /db_xref="GeneID:6760459"
     CDS             439132..440364
                     /gene="fabF"
                     /locus_tag="Sez_0411"
                     /note="similar to ref|YP_060801.1| 3-oxoacyl-(acyl carrier
                     protein) synthase II [Streptococcus pyogenes MGAS10394];
                     Catalyzes the condensation reaction of fatty acid
                     synthesis by the addition to an acyl acceptor of two
                     carbons from malonyl-ACP. Has a preference for short chain
                     acid substrates."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase II
                     FabF"
                     /protein_id="YP_002122798.1"
                     /db_xref="GI:195977554"
                     /db_xref="GeneID:6760459"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAVEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSRMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAMRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAISN
                     TFGFGGHNAVLAFKRWED"
     gene            440366..440839
                     /gene="accB"
                     /locus_tag="Sez_0412"
                     /db_xref="GeneID:6760676"
     CDS             440366..440839
                     /gene="accB"
                     /locus_tag="Sez_0412"
                     /note="similar to ref|YP_603041.1| acetyl-CoA carboxylase
                     biotin carboxyl carrier protein subunit [Streptococcus
                     pyogenes MGAS10750]; This protein is a component of the
                     acetyl coenzyme A carboxylase complex; first, biotin
                     carboxylase catalyzes the carboxylation of the carrier
                     protein and then the transcarboxylase transfers the
                     carboxyl group to form malonyl-CoA."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin carboxyl carrier protein of acetyl-CoA
                     carboxylase AccB"
                     /protein_id="YP_002122799.1"
                     /db_xref="GI:195977555"
                     /db_xref="GeneID:6760676"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPVAAPA
                     PEPVTLHQEVAPISLTQEIVSRQESLPASSDLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            440836..441258
                     /gene="fabZ"
                     /locus_tag="Sez_0413"
                     /db_xref="GeneID:6760458"
     CDS             440836..441258
                     /gene="fabZ"
                     /locus_tag="Sez_0413"
                     /note="similar to dbj|BAB16042.1| similar to Bacillus
                     subtilis hydroxymyristoyl-(acyl carrier protein)
                     dehydratase [Streptococcus equi subsp. zooepidemicus];
                     Involved in saturated fatty acids biosynthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="(3R)-hydroxymyristoyl-[acyl carrier protein]
                     dehydratase FabZ"
                     /protein_id="YP_002122800.1"
                     /db_xref="GI:195977556"
                     /db_xref="GeneID:6760458"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            441293..442656
                     /gene="accC"
                     /locus_tag="Sez_0414"
                     /note="biotin carboxylase AccC; unconfirmed disrupted
                     gene, a potential error in the sequence asssembly"
                     /db_xref="GeneID:6760674"
     gene            442665..443531
                     /gene="accD"
                     /locus_tag="Sez_0416"
                     /db_xref="GeneID:6760457"
     CDS             442665..443531
                     /gene="accD"
                     /locus_tag="Sez_0416"
                     /note="similar to ref|YP_603038.1| acetyl-CoA carboxylase
                     subunit beta [Streptococcus pyogenes MGAS10750]; This
                     protein is a component of the acetyl coenzyme A
                     carboxylase complex; first, biotin carboxylase catalyzes
                     the carboxylation of the carrier protein and then the
                     transcarboxylase transfers the carboxyl group to form
                     malonyl-CoA."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-coenzyme A carboxylase carboxyl
                     transferase subunit beta AccD"
                     /protein_id="YP_002122801.1"
                     /db_xref="GI:195977557"
                     /db_xref="GeneID:6760457"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNIPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPGYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAINER
                     LPVIIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            443528..444298
                     /gene="accA"
                     /locus_tag="Sez_0417"
                     /db_xref="GeneID:6760672"
     CDS             443528..444298
                     /gene="accA"
                     /locus_tag="Sez_0417"
                     /note="similar to ref|YP_280938.1| acetyl-CoA carboxylase
                     subunit alpha [Streptococcus pyogenes MGAS6180]; This
                     protein is a component of the acetyl coenzyme A
                     carboxylase complex; first, biotin carboxylase catalyzes
                     the carboxylation of the carrier protein and then the
                     transcarboxylase transfers the carboxyl group to form
                     malonyl-CoA."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-coenzyme A carboxylase carboxyl
                     transferase subunit alpha AccA"
                     /protein_id="YP_002122802.1"
                     /db_xref="GI:195977558"
                     /db_xref="GeneID:6760672"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIIEMIRSHLIDEITQLQAKSLEELLDQRYQRFRKY"
     gene            complement(444529..445806)
                     /gene="serS"
                     /locus_tag="Sez_0418"
                     /db_xref="GeneID:6760456"
     CDS             complement(444529..445806)
                     /gene="serS"
                     /locus_tag="Sez_0418"
                     /note="similar to ref|NP_269765.1| seryl-tRNA synthetase
                     [Streptococcus pyogenes M1 GAS]; Catalysis of the
                     reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate +
                     L-seryl-tRNA(Ser)."
                     /codon_start=1
                     /transl_table=11
                     /product="seryl-tRNA synthetase SerS"
                     /protein_id="YP_002122803.1"
                     /db_xref="GI:195977559"
                     /db_xref="GeneID:6760456"
                     /translation="MLDLKRIRTDFDAVAAKLKTRGVSEDTLTTLKALDEQRRALLVQ
                     TEELKAQRNIASAAIAQAKRQKKDASQQIADMQQLAANIKVIDAKLADIDQEITSIIT
                     VLPNTPHDSVPIGADEEDNVEIRRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYDELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLELIKPR"
     gene            446391..447458
                     /locus_tag="Sez_0419"
                     /db_xref="GeneID:6760670"
     CDS             446391..447458
                     /locus_tag="Sez_0419"
                     /note="similar to ref|NP_734813.1| hypothetical protein
                     gbs0344 [Streptococcus agalactiae NEM316]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122804.1"
                     /db_xref="GI:195977560"
                     /db_xref="GeneID:6760670"
                     /translation="MRKNVMTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEG
                     EADSYFIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLL
                     FALFGFPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVL
                     LVFAIFSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVY
                     MGSLVVTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPT
                     TLGIYLVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLML
                     FKKLGFQHLLKWVDKKIPFAD"
     gene            complement(447626..448009)
                     /gene="manO"
                     /locus_tag="Sez_0420"
                     /db_xref="GeneID:6760455"
     CDS             complement(447626..448009)
                     /gene="manO"
                     /locus_tag="Sez_0420"
                     /note="similar to ref|YP_280936.1| hypothetical cytosolic
                     protein [Streptococcus pyogenes MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose operon regulator ManO"
                     /protein_id="YP_002122805.1"
                     /db_xref="GI:195977561"
                     /db_xref="GeneID:6760455"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKIARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(448143..449054)
                     /gene="manZ"
                     /locus_tag="Sez_0421"
                     /db_xref="GeneID:6760668"
     CDS             complement(448143..449054)
                     /gene="manZ"
                     /locus_tag="Sez_0421"
                     /note="similar to ref|NP_607833.1| putative
                     mannose-specific phosphotransferase system component IID
                     [Streptococcus pyogenes MGAS8232]; This is a component of
                     the phosphoenolpyruvate-dependent sugar phosphotransferase
                     system (Pts), a major carbohydrate active -transport
                     system."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-Specific Phosphotransferase System
                     Component IID ManZ"
                     /protein_id="YP_002122806.1"
                     /db_xref="GI:195977562"
                     /db_xref="GeneID:6760668"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKIQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(449070..449879)
                     /gene="manY"
                     /locus_tag="Sez_0422"
                     /db_xref="GeneID:6760454"
     CDS             complement(449070..449879)
                     /gene="manY"
                     /locus_tag="Sez_0422"
                     /note="similar to ref|YP_280934.1| PTS system,
                     mannose-specific IIC component [Streptococcus pyogenes
                     MGAS6180]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose-specific IIC component ManY"
                     /protein_id="YP_002122807.1"
                     /db_xref="GI:195977563"
                     /db_xref="GeneID:6760454"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEVVQGVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            complement(450047..451039)
                     /gene="manX"
                     /locus_tag="Sez_0423"
                     /db_xref="GeneID:6760666"
     CDS             complement(450047..451039)
                     /gene="manX"
                     /locus_tag="Sez_0423"
                     /note="similar to ref|YP_001127956.1| putative
                     mannose-specific phosphotransferase system (PTS), IIAB
                     component [Streptococcus pyogenes str. Manfredo]; The
                     phosphoenolpyruvate-dependent sugar phosphotransferase
                     system (PTS), a major carbohydrate active -transport
                     system, catalyzes the phosphorylation of incoming sugar
                     substrates concomitant with their translocation across the
                     cell membrane. This system is involved in mannose
                     transport."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose-specific EIIAB component
                     ManX"
                     /protein_id="YP_002122808.1"
                     /db_xref="GI:195977564"
                     /db_xref="GeneID:6760666"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSMAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            complement(451167..451394)
                     /locus_tag="Sez_0424"
                     /db_xref="GeneID:6760453"
     CDS             complement(451167..451394)
                     /locus_tag="Sez_0424"
                     /note="similar to ref|XP_954798.1| glutamate-cysteine
                     ligase, putative [Theileria annulata strain Ankara]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_002122809.1"
                     /db_xref="GI:195977565"
                     /db_xref="GeneID:6760453"
                     /translation="MKANETIVLQKTMVFLMPFPSIDERISNIFVIFQHIFFFMRHKN
                     PFIINILLIRQRIMKIFSYFVRFFRKGLIFK"
     gene            complement(451391..452203)
                     /locus_tag="Sez_0425"
                     /db_xref="GeneID:6760663"
     CDS             complement(451391..452203)
                     /locus_tag="Sez_0425"
                     /note="similar to ref|NP_607830.1| hypothetical protein
                     spyM18_1809 [Streptococcus pyogenes MGAS8232]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hydrolase (HAD superfamily)"
                     /protein_id="YP_002122810.1"
                     /db_xref="GI:195977566"
                     /db_xref="GeneID:6760663"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQAKGHEVIISTG
                     RPYRMALDYYLQLELKTPMISFNGSLTHLPEQRWKYEHNVTLDKAYLLKLLAVQEDFQ
                     MDFIASEYRKAFYITMNRPESIDPNLFGVEAITPDMALQIDKITQDPNALLMQTHHED
                     KYALAKAMRAFFKDEIEVDSWGGPLNILEMSPKNINKAYALKYLLSIYNKEPKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPFADQQLAYSNEEDGVARKLEELFL"
     gene            452462..453922
                     /locus_tag="Sez_0426"
                     /db_xref="GeneID:6760452"
     CDS             452462..453922
                     /locus_tag="Sez_0426"
                     /note="similar to ref|YP_060789.1| Guanine