An assertion is a statement about the purpose of a particular feature in a genome. The most common type of assertion is the assignment of a FunctionalRole to a ProteinEncodingGene; however, other types of assertions are possible, and assertions can be made for any type of feature, not just ProteinEncodingGenes. The process of making an assertion is called annotation; however, it is not uncommon for the terms annotation and assertion to be used interchangeably.

Inside the NmpdrWebsite, a single assertion is selected for each feature and given the elevated role of functional assignment. In the GenomeViewer, the functional assignment is also referred to as the function or current assignment of a feature. In the Annotation Overview on the SeedViewerAnnotationPage? , you can use the history button placed next to the current assignment to see all of the annotations for the feature. This is shown in the picture below.

Screen fragment of annotation overview, showing history

It is often useful to know what other assertions have been made about a feature. This information is collected in the AnnotationClearinghouse (see AliasesAndEquivalentGenes). In the picture below, you can see the clearinghouse results for fig|273036.3.peg.1023. Note that the clearinghouse includes assertions made by other institutions.

Submitted assertions for fig|273036.3.peg.1023
Topic revision: r3 - 18 Aug 2008 - 15:31:23 - BruceParrello
 
NMPDR is a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.