Glossary of Useful Terms

  • Alias An alias is a gene identifier from an outside organization or database. Inside the NMPDR's data structures, the FigId is used for each gene. Each gene also has a list ...
  • Assertion An assertion is a statement about the purpose of a particular feature in a genome . The most common type of assertion is the assignment of a FunctionalRole ...
  • BidirectionalBestHit BBH example: the black arrows represent best hits. The best hit of a particular gene to a target genome is the gene in that genome that represents a best ...
  • CoreOrganisms NMPDR is a Bioinformatics Resource Center. Each center specializes in certain pathogens. In NMPDR, we call these the core genomes or NMPDR genomes . The genomes ...
  • FastaFormat FASTA format is a standard format for encoding DNA or protein sequences. A FASTA file generally contains one or more sequences in FASTA format. A single sequence ...
  • Feature Features and Genes A feature is anything that can be mapped onto a strand of DNA, and is defined by its start and stop location. Feature is a catch all, general ...
  • FigFam FigFams are sets of ProteinSequences that are similar along their full length. Proteins are thought of as implementing one or more abstract FunctionalRoles. All of ...
  • FigId Every gene in the NMPDR database has a unique FigId. It has four parts, as shown in the diagram below. /FigID.png The prefix identifies the fact that this ...
  • FunctionalRole The functional role of a feature is the task it performs in the host organism. The role is stored in the NMPDR database as a descriptive phrase. Some functional ...
  • Genome Screen shot from the GenomeViewer showing a section of genome A genome is a related collection of DNA. In most cases, a genome represents the DNA for a single sequenced ...
  • Homologs Two features are said to be similar or homologous if they share a nearly identical DNA sequence. Two similar features are called homologs , and the set of one ...
  • Motif A protein motif is a small section of a protein that has a known function, is folded independently of the rest if the protein, or functions as a docking site. The ...
  • ProteinEncodingGene Protein encoding gene (PEG), protein coding sequence (CDS), and open reading frame (ORF) are synonymous terms. Protein encoding genes are commmonly described as structural ...
  • Subsystem Subsystem diagram for , an example of a subsystem based on a metabolic pathway. Subsystems are a generalization of the concept of pathways, and they have two components ...
Topic revision: r7 - 06 Apr 2008 - 04:36:09 - BruceParrello
 
NMPDR is a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.