Two features are said to be similar or homologous if they share a nearly identical DNA sequence. Two similar features are called homologs, and the set of one particular feature's homologs is called its similarities. In bioinformatics? , similarities are the fundamental tool for reasoning about genes in new genomes. With millions of features in our database, it is not possible to compute similarities on demand. Instead, similarities are computed as new genomes make their way into the system via the pipeline and stored on an external SimilaritiesServer? .
Topic revision: r2 - 17 Apr 2008 - 08:23:49 - BruceParrello
NMPDR is a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.