Taxonomy: Bacteria; Firmicutes; Mollicutes; Mycoplasmataceae;

Mycoplasma

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Mycoplasma

I. Organism Information

A. Taxonomy Information

1. Genus

a. Mycoplasma

i. Taxonomy ID: 2093

ii. Description:

Mycoplasma is one of several genera within the Mollicutes, a class of bacteria that have small genomes, lack a cell wall, and have low GC-content. Their genome size ranges from 0.6 - 1.35 megabase-pairs. Mollicutes are parasites or commensals of humans, other animals including insects, and plants; the genus Mycoplasmas, by definition, are restricted to vertebrate hosts. Because Mycoplasmas lack cell walls, they are unaffected by most antibiotics such as penicillin that target cell wall synthesis. They can be parasitic or saprophytic. Several species are pathogenic in humans, including M. pneumoniae, which is an important cause of pneumonia and other respiratory disorders, and M. genitalium, which is believed to be involved in pelvic inflammatory diseases. They may cause or contribute to some cancers.

iii. Variants

Mycoplasma genitalium G-37
Taxonomy ID: 243273

Mycoplasma penetrans HF-2
Taxonomy ID: 272633

Mycoplasma pneumoniae M129
Taxonomy ID: 272634

II. References

1. Fraser, C. M., J. D. Gocayne, O. White, M. D. Adams, R. A. Clayton, R. D. Fleischmann, C. J. Bult, A. R. Kerlavage, G. Sutton, J. M. Kelley, and a. et. 1995. The minimal gene complement of Mycoplasma genitalium. Science 270:397-403.

2. Maniloff, J. 2002. Phylogeny and Evolution, p. 31-44. In Razin, S., and R. Herrmann (eds.), Molecular Biology and Pathogenicity of Mycoplasmas, Kluwer Academic/Plenum, New York.

3. Tsai S, Wear D.J., Shih J.W., Lo, S.C. 1995. Mycoplasmas and oncogenesis: persistent infection and multistage malignant transformation. Proc Natl Acad Sci U S A; 92(22):10197-201

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Mycoplasma - Google News

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New mycoplasma detection kit to help biopharma manufacturing - Alibaba News Channel


Alibaba News Channel

New mycoplasma detection kit to help biopharma manufacturing
Alibaba News Channel, NEW YORK - 16 hours ago
Applied Biosystems has developed the MicroSEQ detection platform, which could revolutionise the detection of bacterial mycoplasma in industrial scale ...

BioReliance Announces First Commercial Use of HyMy Assay - Business Wire (press release)


BioReliance Announces First Commercial Use of HyMy Assay
Business Wire (press release), CA - Nov 20, 2008
In addition to its speed, HyMy is superior to other mycoplasma detection methods because it can determine the viability or non-viability of more than 60 ...

What's Going Around - WHSV


What's Going Around
WHSV, VA - Nov 19, 2008
Walking pneumonia is caused by a mild bacterial infection called mycoplasma, which causes coughing and chest congestion for several weeks. ...

VNTR analysis reveals unexpected genetic diversitywithin ... - 7thSpace Interactive (press release)


VNTR analysis reveals unexpected genetic diversitywithin ...
7thSpace Interactive (press release), NY - Nov 8, 2008
Mycoplasma agalactiae is the main cause of contagious agalactia, a serious disease of sheep and goats, which has major clinical and economic impacts. ...

Free range egg production problems - Farming UK


Free range egg production problems
Farming UK, UK - Nov 14, 2008
One of the most common bacterial infections to cause egg production problems and shell quality problems in laying flocks is Mycoplasma, both Mycoplasma ...

Achilles' Heel Of Pancreatic Cancer Discovered - Science Daily (press release)


Achilles' Heel Of Pancreatic Cancer Discovered
Science Daily (press release) - Nov 6, 2008
... the researchers depleted arginine levels in cultures of pancreatic cell lines using arginine deiminase, an enzyme isolated from a Mycoplasma bacteria. ...

Resurrecting Mammoths Gets One Step Closer - Newsweek


Resurrecting Mammoths Gets One Step Closer
Newsweek - Nov 19, 2008
The largest such synthetic genome yet synthesized is the measly 582970 nucleotide one of the bacterium Mycoplasma genitalium. For mammoths, you d need to ...

AgriLabs: New Mycomune R Approved To Help Prevent Respiratory ... - CattleNetwork.com


AgriLabs: New Mycomune R Approved To Help Prevent Respiratory ...
CattleNetwork.com, KS - Oct 31, 2008
"Mycomune R offers producers significant advantages over previous products for preventing Mycoplasma bovis," said Jessica Newberry, DVM with Biomune Co. ...

What's Going Around - WSAZ-TV


What's Going Around
WSAZ-TV, WV - Nov 4, 2008
Mycoplasma, a respiratory illness, is also still in the mix in Ashland. The croup, a virus causing a loud distinctive cough, is also on the list of what's ...

Metabolic interruption for Pancreatic Cancer discovered - HealthJockey.com


HealthJockey.com

Metabolic interruption for Pancreatic Cancer discovered
HealthJockey.com, India - Nov 7, 2008
This experiment was done with the help of an enzyme cut-off from the Mycoplasma bacteria - arginine deiminase. In order to increase its circulatory time and ...

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Mycoplasma genome sequence annotation status: click numbers to browse lists of genes or subsystems

Strain annotated in NMPDR Genome size, bp Protein Encoding Genes (PEGs) Named genes in subsystems Named genes not in subsystems Hypothetical genes in subsystems Hypothetical genes not in subsystems Subsystems RNAs
Mycoplasma capricolum subsp. capricolum ATCC 27343 1,010,023 832 353(40.7%) 297(34.2%) 5(0.6%) 213(24.5%) 145 42
Mycoplasma gallisepticum R 996,422 726 346(45.1%) 223(29.0%) 3(0.4%) 196(25.5%) 146 43
Mycoplasma genitalium G-37 580,074 484 300(57.4%) 144(27.5%) 2(0.4%) 77(14.7%) 125 43
Mycoplasma hyopneumoniae 232 892,758 693 311(42.8%) 171(23.5%) 4(0.6%) 241(33.1%) 134 37
Mycoplasma hyopneumoniae 7448 920,079 663 308(44.2%) 174(25.0%) 4(0.6%) 211(30.3%) 132 37
Mycoplasma hyopneumoniae J 897,405 665 306(43.8%) 181(25.9%) 4(0.6%) 208(29.8%) 132 36
Mycoplasma mobile 163K 777,079 633 309(47.0%) 312(47.5%) 6(0.9%) 30(4.6%) 143 36
Mycoplasma mycoides subsp. mycoides SC str. PG1 1,211,703 1,021 384(36.2%) 388(36.5%) 4(0.4%) 286(26.9%) 154 45
Mycoplasma penetrans HF-2 1,358,633 1,039 372(34.4%) 433(40.1%) 9(0.8%) 266(24.6%) 150 34
Mycoplasma pneumoniae M129 816,394 689 323(44.2%) 190(26.0%) 3(0.4%) 215(29.4%) 138 43
Mycoplasma pulmonis UAB CTIP 963,879 782 349(42.5%) 237(28.9%) 4(0.5%) 231(28.1%) 133 37
Mycoplasma synoviae 53 799,476 672 344(48.2%) 205(28.7%) 5(0.7%) 160(22.4%) 141 45
Topic revision: r5 - 16 May 2008 - 06:03:14 - BruceParrello
 
NMPDR is a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.