Mycoplasma

Mycoplasma

A. Taxonomy Information

1. Genus

a. Mycoplasma

i. Taxonomy ID: 2093

ii. Description:

Mycoplasma is one of several genera within the Mollicutes, a class of bacteria that have small genomes, lack a cell wall, and have low GC-content. Their genome size ranges from 0.6 - 1.35 megabase-pairs. Mollicutes are parasites or commensals of humans, other animals including insects, and plants; the genus Mycoplasmas, by definition, are restricted to vertebrate hosts. Because Mycoplasmas lack cell walls, they are unaffected by most antibiotics such as penicillin that target cell wall synthesis. They can be parasitic or saprophytic. Several species are pathogenic in humans, including M. pneumoniae, which is an important cause of pneumonia and other respiratory disorders, and M. genitalium, which is believed to be involved in pelvic inflammatory diseases. They may cause or contribute to some cancers.

iii. Variants

Mycoplasma genitalium G-37
Taxonomy ID: 243273

Mycoplasma penetrans HF-2
Taxonomy ID: 272633

Mycoplasma pneumoniae M129
Taxonomy ID: 272634

II. References

1. Fraser, C. M., J. D. Gocayne, O. White, M. D. Adams, R. A. Clayton, R. D. Fleischmann, C. J. Bult, A. R. Kerlavage, G. Sutton, J. M. Kelley, and a. et. 1995. The minimal gene complement of Mycoplasma genitalium. Science 270:397-403.

2. Maniloff, J. 2002. Phylogeny and Evolution, p. 31-44. In Razin, S., and R. Herrmann (eds.), Molecular Biology and Pathogenicity of Mycoplasmas, Kluwer Academic/Plenum, New York.

3. Tsai S, Wear D.J., Shih J.W., Lo, S.C. 1995. Mycoplasmas and oncogenesis: persistent infection and multistage malignant transformation. Proc Natl Acad Sci U S A; 92(22):10197-201

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Mycoplasma - Google News

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