Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;

Staphylococcus

Staphylococcus search

Read about Staphylococcus:

Hide info

Staphylococcus aureus

I. Organism Information

A. Taxonomy Information

1. Species

a. Staphylococcus aureus

i. Taxonomy ID: 1280

ii. Description:

Staphylococcus aureus is a Gram-positive pathogen that causes a wide range of diseases, and is becoming increasingly resistant to antibiotics (1). These resistant bacteria are called methicillin-resistant Staphylococcus aureus, or MRSA. S. aureus is responsible for a variety of ailments, including carbuncles, food poisoning, wound and medical device-related infections, bacteremia, necrotizing pneumonia, and endocarditis (2). S. aureus forms a fairly large yellow colony on rich medium and is hemolytic on blood agar. Staphylococci are facultative anaerobes that ferment glucose to lactate. The bacteria are catalase-positive and oxidase-negative. S. aureus can grow at a temperature range of 15 to 45 degrees and at NaCl concentrations as high as 15 percent. Almost all strains of S. aureus produce the enzyme coagulase. S. aureus should always be considered a potential pathogen (3).

To contribute more information, please contact help@nmpdr.org

iii. Variants

Staphylococcus aureus subsp. aureus
Taxonomy ID: 46170

Staphylococcus aureus subsp. aureus COL
Taxonomy ID: 93062
Parent: Staphylococcus aureus subsp. aureus

Staphylococcus aureus subsp. aureus MRSA252
Taxonomy ID: 282458
Parent: Staphylococcus aureus subsp. aureus

Staphylococcus aureus subsp. aureus MSSA476
Taxonomy ID: 282459
Parent: Staphylococcus aureus subsp. aureus

Staphylococcus aureus subsp. aureus MW2
Taxonomy ID: 196620

Parent: Staphylococcus aureus subsp. aureus

Staphylococcus aureus subsp. aureus Mu50
Taxonomy ID: 158878
Parent: Staphylococcus aureus subsp. aureus

Staphylococcus aureus subsp. aureus N315
Taxonomy ID: 158879
Parent: Staphylococcus aureus subsp. aureus

B. Lifecycle and Morphology

1. (To contribute to this description of the infection cycle, please contact help@nmpdr.org)

a. Shape:

Cocci 0.5-1.0 μm in diameter. Cells occur singly or in pairs. Division is in two planes, giving rise to clusters. Colonies are smooth, raised, glistening, circular, entire and translucent. Single colonies may obtain a size of 6-8 mm in diameter (4).

b. Picture:

SEM of Staphylococcus aureus
SEM of numerous clumps of methicillin-resistant Staphylococcus aureus bacteria, commonly referred to by the acronym, MRSA (magnified 9560x), by Janice Carr, CDC

C. Genome Summary

1. Genome of Staphylococcus aureus subsp. aureus COL

a. Chromosome

i. Genbank Accession Number: NC_002951
ii. Size: 2,809,422 bp
iii. S. aureus COL is an early methicillin-resistant isolate (5).

b. Plasmid pT181

i. Genbank Accession Number: NC_006629
ii. Size: 4,440 bp



II. References

1.  Sanger Institute

2.  Holden MT, Feil EJ, Lindsay JA, Peacock SJ, Day NP, Enright MC, Foster TJ, Moore CE, Hurst L, Atkin R, Barron A, Bason N, Bentley SD, Chillingworth C, Chillingworth T, Churcher C, Clark L, Corton C, Cronin A, Doggett J, Dowd L, Feltwell T, Hance Z, Harris B, Hauser H, Holroyd S, Jagels K, James KD, Lennard N, Line A, Mayes R, Moule S, Mungall K, Ormond D, Quail MA, Rabbinowitsch E, Rutherford K, Sanders M, Sharp S, Simmonds M, Stevens K, Whitehead S, Barrell BG, Spratt BG, Parkhill J. (2004) Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc. Natl. Acad. Sci. USA. 101: 9786-91.

3.   http://textbookofbacteriology.net/staph.html


4.   Bergey's Manual of Determinative Bacteriology, 9th edition. John G. Holt, Noel R. Krieg, Peter H.A. Sneath, James T. Staley, and Stanley T. Williams, editors. Baltimore: Williams and Wilkins, 1994, pp. 518.

5.   Gill SR, Fouts DE, Archer GL, Mongodin EF, Deboy RT, Ravel J, Paulsen IT, Kolonay JF, Brinkac L, Beanan M, Dodson RJ, Daugherty SC, Madupu R, Angiuoli SV, Durkin AS, Haft DH, Vamathevan J, Khouri H, Utterback T, Lee C, Dimitrov G, Jiang L, Qin H, Weidman J, Tran K, Kang K, Hance IR, Nelson KE, and Fraser CM. (2005) Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain. J. Bacteriol. 187: 2426-2438.

Hide info

Hide info

Staphylococcus - Google News

©2016 Google

Researchers Discover New Way to Attack Staphylococcus aureus - Sci-News.com


Sci-News.com

Researchers Discover New Way to Attack Staphylococcus aureus
Sci-News.com
Staphylococcus aureus is a common bacterium that can normally be found in the nose, on the skin or in the lower intestine of any person. This germ is the leading cause of recurrent infections in humans that include pneumonia, bacteremia, osteomyelitis, ...
Researchers find new way to kill Staphylococcus aureus bacteriaNews-Medical.net
New findings detail how beneficial bacteria in the nose suppress pathogenic bacteriaScience Daily
Beneficial bacteria in nose can suppress pathogenic bacteriaTimes of India
Wellcome Trust -Cosmos
all 10 news articles »

Market Research Report on China Methicillin-Resistant Staphylococcus Aureus (MRSA) Infections Industry Analysis ... - Medgadget (blog)


Market Research Report on China Methicillin-Resistant Staphylococcus Aureus (MRSA) Infections Industry Analysis ...
Medgadget (blog)
Researchmoz added Most up-to-date research on China Methicillin-Resistant Staphylococcus Aureus (MRSA) Infections Industry 2016 Market Research Report to its huge collection of research reports. The China Methicillin-Resistant Staphylococcus ...

Methicillin-resistant Staphylococcus aureus (MRSA) - Market Insights, Epidemiology and Market Forecast-2023 - Medgadget (blog)


Methicillin-resistant Staphylococcus aureus (MRSA) - Market Insights, Epidemiology and Market Forecast-2023
Medgadget (blog)
DelveInsights Methicillin-resistant Staphylococcus aureus (MRSA) Market Insights, Epidemiology and Market Forecast-2023 Reports provides an overview of the disease and global market trends of the Methicillin-resistant Staphylococcus aureus (MRSA) for ...

and more »

Green monkeys acquired Staphylococcus aureus from humans - Science Daily


Winona Daily News

Green monkeys acquired Staphylococcus aureus from humans
Science Daily
... Mark J Pallen, Edward J Feil, and Martin Antonio. Whole-genome sequencing reveals transmission of Staphylococcus aureus from humans to green monkeys in The Gambia. Applied and Environmental Microbiology, July 2016 DOI: 10.1128/AEM.01496-16 ...
Humans give bacterial infection to monkeys while feeding them peanutsThe Independent
Humans Can Pass Staph Germs to Monkeys - HealthDayHealthDay
How Does Copper Interact with Staph aureus?Contagionlive.com

all 5 news articles »

Green monkeys acquired Staphylococcus aureus from humans ... - EurekAlert (press release)


EurekAlert (press release)

Green monkeys acquired Staphylococcus aureus from humans ...
EurekAlert (press release)
Already it's known that many deadly diseases that afflict humans were originally acquired through contact with animals. However new research from the ...

and more »

How staphylococci trigger blood poisoning - Science Daily


How staphylococci trigger blood poisoning
Science Daily
Septicemia or blood poisoning caused by Staphylococcus aureus leads to thousands of deaths each year in Germany alone. Just how the infection begins -- and can lead to multiple organ failure -- was little understood until now. There are few options for ...

AmpliPhi Biosciences Completes Enrollment of Its Investigational ... - Business Wire (press release)


AmpliPhi Biosciences Completes Enrollment of Its Investigational ...
Business Wire (press release)
AmpliPhi Biosciences Corporation (NYSEMKT:APHB), a global leader in the development of bacteriophage-based antibacterial therapies to treat drug-resis.

and more »

New Antibiotic Found in Human Noses - VOA Learning English - Voice of America (blog)


Voice of America (blog)

New Antibiotic Found in Human Noses - VOA Learning English
Voice of America (blog)
The discovery of an antibiotic compound in the nose means it could be a great source for making the valuable drugs. New antibiotics are needed because the ...

and more »

The nose knows how to kill MRSA - Nature.com


Nature.com

The nose knows how to kill MRSA
Nature.com
The potential new soldier in the fight against MRSA is a molecule called lugdunin produced by the bacterium Staphylococcus lugdunensis, report Andreas Peschel and colleagues at the University of T bingen, Germany, on 27 July in Nature.
Antibiotic Found in Noses Here's What You Need to KnowNational Geographic
'Nose-y' Bacteria Could Yield A New Way To Fight InfectionNPR
Human nose holds novel antibiotic effective against multiresistant pathogensScience Daily
The Hindu -Los Angeles Times -TIME -Northeastern University
all 156 news articles »

Antibiotic Resistance Breakthrough: New Treatment Prevents Bacterial Skin Infections - Medical Daily


Medical Daily

Antibiotic Resistance Breakthrough: New Treatment Prevents Bacterial Skin Infections
Medical Daily
Researchers at the University of Sheffield have developed an experimental treatment designed to protect skin wounds from being infected by various multidrug-resistant strains of Staphylococcus aureus. Rather than attacking the germs, however, the ...

Hide info

Staphylococcus genome sequence annotation status: click numbers to browse lists of genes or subsystems

Strain annotated in NMPDR Phenotype Genome size, bp Protein Encoding Genes (PEGs) Sort Named genes in subsystems Named genes not in subsystems Hypothetical genes in subsystems Hypothetical genes not in subsystems Subsystems RNAs
Staphylococcus aureus RF122 Bovine mastitis 2,742,531 2,523 1213(45.4%) 731(27.4%) 113(4.2%) 615(23.0%) 316 110
Staphylococcus aureus subsp. aureus COL methicillin resistant, hospital acquired (MRSA) 2,813,862 2,622 1247(44.8%) 718(25.8%) 98(3.5%) 722(25.9%) 330 108
Staphylococcus aureus subsp. aureus JH1 vancomycin susceptible, hospital acquired (MRSA) 2,879,577 2,685 1194(43.4%) 779(28.3%) 110(4.0%) 666(24.2%) 314 172
Staphylococcus aureus subsp. aureus JH9 vancomycin nonsusceptible, isogenic to JH1, hospital acquired (MRSA, VISA) 2,862,918 2,675 1202(43.9%) 773(28.2%) 108(3.9%) 657(24.0%) 316 165
Staphylococcus aureus subsp. aureus MRSA252 methicillin resistant, hospital acquired (MRSA) 2,902,619 2,663 1254(45.7%) 756(27.5%) 77(2.8%) 659(24.0%) 338 110
Staphylococcus aureus subsp. aureus MSSA476 methicillin susceptible, community acquired 2,820,454 2,609 1231(45.1%) 763(28.0%) 82(3.0%) 652(23.9%) 335 157
Staphylococcus aureus subsp. aureus MW2 methicillin resistant, community acquired (CA-MRSA) 2,820,462 2,644 1202(43.7%) 790(28.7%) 92(3.3%) 669(24.3%) 337 53
Staphylococcus aureus subsp. aureus Mu3   2,880,168 2,495 1094(43.7%) 768(30.7%) 90(3.6%) 549(22.0%) 296 108
Staphylococcus aureus subsp. aureus Mu50 methicillin and vancomycin resistant, hospital acquired (MRSA, VRSA) 2,903,147 2,771 1293(44.0%) 818(27.9%) 142(4.8%) 683(23.3%) 337 108
Staphylococcus aureus subsp. aureus N315 methicillin resistant, hospital acquired (MRSA) 2,839,469 2,648 1279(45.3%) 814(28.9%) 90(3.2%) 638(22.6%) 340 110
Staphylococcus aureus subsp. aureus NCTC 8325 lab strain 2,821,361 2,895 1222(39.9%) 832(27.1%) 110(3.6%) 901(29.4%) 320 109
Staphylococcus aureus subsp. aureus USA300 methicillin resistant, community acquired (CA-MRSA) 2,917,469 2,607 1223(44.1%) 833(30.1%) 86(3.1%) 629(22.7%) 316 105
Staphylococcus aureus subsp. aureus str. Newman   2,878,897 2,523 1077(42.6%) 782(30.9%) 71(2.8%) 599(23.7%) 293 109
Staphylococcus epidermidis ATCC 12228   2,564,615 2,472 1147(44.7%) 723(28.2%) 47(1.8%) 647(25.2%) 325 118
Staphylococcus epidermidis RP62A   2,643,840 2,529 1122(42.7%) 678(25.8%) 45(1.7%) 780(29.7%) 316 120
Staphylococcus haemolyticus JCSC1435   2,697,861 2,694 1164(41.8%) 773(27.7%) 53(1.9%) 796(28.6%) 323 111
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305   2,577,899 2,517 1140(43.7%) 765(29.3%) 42(1.6%) 662(25.4%) 327 122
Topic revision: r6 - 23 Aug 2008 - 11:08:12 - TWiki Guest
 
Notice to NMPDR Users - The NMPDR BRC contract has ended and bacterial data from NMPDR has been transferred to PATRIC (http://www.patricbrc.org), a new consolidated BRC for all NIAID category A-C priority pathogenic bacteria. NMPDR was a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.