Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae;

Treponema

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Treponema

I. Organism Information

A. Taxonomy Information

1. Species

a. Treponema pallidum

i. Taxonomy ID: 157

ii. Description:

Treponema pallidum is a motile spirochaete that is generally acquired by close sexual contact and can also be transmitted to a fetus during the later stages of pregnancy, giving rise to congenital syphilis. The helical structure of T. pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. It gains access to host's blood and lymph systems through tissue and mucus membranes. Treponema pallidum subsp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of inside a host.


iii. Variants

Treponema pallidum subsp. pallidum str. Nichols
Taxonomy ID: 243276


II. References

1.  Lafond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006 Jan;19(1):29-49.

2. Peeling RW, Hook EW 3rd. The pathogenesis of syphilis: the Great Mimicker, revisited. J Pathol. 2006 Jan;208(2):224-32.

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syphilis - Google News

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Syphilis cases on the rise in Rockingham County Local News ... - The Daily News of Newburyport


Syphilis cases on the rise in Rockingham County Local News ...
The Daily News of Newburyport
Rockingham County, New Hampshire, is in the midst of a syphilis outbreak, state officials reported Thursday.

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New Hampshire health officials warn of syphilis resurgence - Concord Monitor


Concord Monitor

New Hampshire health officials warn of syphilis resurgence
Concord Monitor
The sexually transmitted disease syphilis is making a resurgence in New Hampshire after almost disappearing a decade ago, and doctors are being warned to look out for it. Health care providers haven't seen syphilis for a long time. It may not be on ...
New Hampshire Experiencing Syphilis OutbreakCBS Boston / WBZ
NH Sees Spike in Cases of SyphilisNew Hampshire Public Radio
New Hampshire experiences syphilis outbreak WGMEWGME
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AIDS Healthcare Foundation warns of 'Syphilis Tsunami' - Wisconsin Gazette


AIDS Healthcare Foundation warns of 'Syphilis Tsunami'
Wisconsin Gazette
AIDS Healthcare Foundation recently launched an outdoor advertising campaign, with new billboards warning of a Syphilis Tsunami." AHF's Syphilis Tsunami campaign references the world-renowned landscape print The Great Wave off Kanagawa by ...

What is syphilis, why is called the French disease, can it lead to infertility, what are the cures and how is it caused? - The Sun


The Sun

What is syphilis, why is called the French disease, can it lead to infertility, what are the cures and how is it caused?
The Sun
Syphilis is a curable bacterial infection that can cause headaches, joint pains, tiredness and fever. It's sometimes known as the 'French disease' as the first written records of an outbreak occurred in 15th Century Naples, following a French invasion ...

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Syphilis: a Mysterious and Serious Ancient Disease RAPS - Regulatory Focus


Regulatory Focus

Syphilis: a Mysterious and Serious Ancient Disease RAPS
Regulatory Focus
This article alerts regulatory professionals to the continued presence of what may be a "forgotten" disease syphilis. Although syphilis is unique and may be ...
Syphilis: What is it, symptoms, treatment and how it is spread Metro ...Metro

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Syphilis 'not a disease of the past': STD has been on the rise in ... - Charleston Post Courier


Charleston Post Courier

Syphilis 'not a disease of the past': STD has been on the rise in ...
Charleston Post Courier
This 1967 image shows the hands of a patient who had been diagnosed with a secondary syphilitic infection. The secondary stage of syphilis is characterized by ...

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Services like Planned Parenthood important as syphilis cases on the rise Opinion - NJ.com


NJ.com

Services like Planned Parenthood important as syphilis cases on the rise Opinion
NJ.com
Especially harrowing to me and the communities I represent is the drastic increase in cases of syphilis. Across the country, syphilis is on the rise after being nearly eliminated; the number of new cases is higher than it's been in more than 20 years ...
The Man Who Secretly Taped Planned Parenthood Could Be Going To Prison Alongside His Criminal LawyersBuzzFeed News

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Reports Show Syphilis is on the Rise - Gay Pop Buzz - Gay Pop Buzz (blog)


Gay Pop Buzz (blog)

Reports Show Syphilis is on the Rise - Gay Pop Buzz
Gay Pop Buzz (blog)
Reports from Public Health England show that syphilis is on the rise, at the highest rates since 1949, and that gay men are most susceptible.
Gay and bisexual men warned as cases of syphilis hit highest levels ...PinkNews
STIs a major concern for Ministry Of Health -- NationNews Barbados ...Nation News
STD alarm Barbados TodayBarbados Today

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Ask the Doctor: Syphilis Outbreak in Washoe County - KTVN Channel 2 - Reno Tahoe Sparks News, Weather, Video - KTVN


KTVN

Ask the Doctor: Syphilis Outbreak in Washoe County - KTVN Channel 2 - Reno Tahoe Sparks News, Weather, Video
KTVN
According to the Washoe County Health District, the primary lesion of syphilis usually appears about 10 to 90 days after exposure. Medical experts say patients with any genital ulcer should have a syphilis serology and a herpes culture during their ...

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Cases of syphilis hit highest level in England since 1949 - The Guardian


The Guardian

Cases of syphilis hit highest level in England since 1949
The Guardian
The number of cases of syphilis in England have reached the highest level since 1949, figures show. Cases of the infection have almost doubled since 2012, according to data from Public Health England (PHE). In 2016 there were 5,920 syphilis diagnoses, ...
Report: England Syphilis Cases Reach Highest Level Since 1949Newsmax
Syphilis cases hit highest level since 1949 amid rise in risky sexTelegraph.co.uk
England: Syphilis cases up 12 percent, Most cases in nearly 70 yearsOutbreak News Today
Daily Mail -Mirror.co.uk
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Treponema genome sequence annotation status: click numbers to browse lists of genes or subsystems

Strain annotated in NMPDR Genome size, bp Protein Encoding Genes (PEGs) Sort Named genes in subsystems Named genes not in subsystems Hypothetical genes in subsystems Hypothetical genes not in subsystems Subsystems RNAs
Treponema denticola ATCC 35405 2,843,201 2,769 717(25.4%) 983(34.8%) 9(0.3%) 1119(39.6%) 251 52
Treponema pallidum subsp. pallidum str. Nichols 1,138,011 1,057 454(41.4%) 564(51.4%) 1(0.1%) 78(7.1%) 183 82

Topic revision: r3 - 02 Mar 2009 - 00:03:21 - TWiki Guest
 
Notice to NMPDR Users - The NMPDR BRC contract has ended and bacterial data from NMPDR has been transferred to PATRIC (http://www.patricbrc.org), a new consolidated BRC for all NIAID category A-C priority pathogenic bacteria. NMPDR was a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.