Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae;

Treponema

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Treponema

I. Organism Information

A. Taxonomy Information

1. Species

a. Treponema pallidum

i. Taxonomy ID: 157

ii. Description:

Treponema pallidum is a motile spirochaete that is generally acquired by close sexual contact and can also be transmitted to a fetus during the later stages of pregnancy, giving rise to congenital syphilis. The helical structure of T. pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. It gains access to host's blood and lymph systems through tissue and mucus membranes. Treponema pallidum subsp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of inside a host.


iii. Variants

Treponema pallidum subsp. pallidum str. Nichols
Taxonomy ID: 243276


II. References

1.  Lafond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006 Jan;19(1):29-49.

2. Peeling RW, Hook EW 3rd. The pathogenesis of syphilis: the Great Mimicker, revisited. J Pathol. 2006 Jan;208(2):224-32.

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syphilis - Google News

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Syphilis cases expected to rise in Tulsa after outbreak in Oklahoma County - Tulsa World


Tulsa World

Syphilis cases expected to rise in Tulsa after outbreak in Oklahoma County
Tulsa World
Reports of syphilis, a curable infection, have grown across the state since an outbreak was declared in the Oklahoma City area earlier this year. Although the data for 2017 haven't been released, health officials believe the epidemic is likely to have ...

Health Department issues Syphilis Alert for Lubbock County - KCBD ... - KCBD-TV


News/Talk 790 KFYO

Japan Is Enlisting Sailor Moon To Help Ward Off Syphilis - Geek


Geek

Japan Is Enlisting Sailor Moon To Help Ward Off Syphilis
Geek
Japan has a syphilis problem. The United States has its own set of STD troubles, too. But Japan is experiencing a meteoric rise when it comes to complications from syphilis in the country, especially when it comes to young women. That's why the country ...

Lab notes: neutron stars collide; sexism and syphilis the week in science - The Guardian


The Guardian

Lab notes: neutron stars collide; sexism and syphilis the week in science
The Guardian
Lab notes: neutron stars collide; sexism and syphilis the week in science. Artist's impression of two neutron stars colliding on Monday. Artist's impression of two neutron stars colliding on Monday, an event 'seen' for the first time, in both ...

ITV's Victoria illustrates how 19th-century sexism helped syphilis to spread - The Guardian (blog)


The Guardian (blog)

ITV's Victoria illustrates how 19th-century sexism helped syphilis to spread
The Guardian (blog)
Historically, syphilis was extremely difficult to cure. Often patients would think that their disease had disappeared or been cured, only to have their bodies betray them with a resurgence of symptoms. This was the story outlined in Sunday night's ...

Doctors See A Surge In Babies With Syphilis-Associated Birth Defects - HuffPost


HuffPost

Doctors See A Surge In Babies With Syphilis-Associated Birth Defects
HuffPost
When you have congenital syphilis occurring, it means there has been a breakdown in the whole medical system that these cases are not being diagnosed until a baby is born, when they should be diagnosed antenatally or even before then, said Dr.
Rate of syphilis nearly doubles in Alachua CountyGainesville Sun
Sacramento County fights rising tide of STDs including syphilis and gonorrheaSacramento Bee
In the U.S., 110 Million S.T.D. Infections - The New York TimesNew York Times
cleveland.com -Infectious Disease Advisor -Santa Barbara Independent -Centers for Disease Control and Prevention
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Syphilis, chlamydia, and gonorrhea on the rise in King County - KING5.com


KING5.com

Syphilis, chlamydia, and gonorrhea on the rise in King County
KING5.com
King County saw the number of syphilis, gonorrhea, and chlamydia cases rise from 2015-16, according to a report from Seattle & King County Public Health. Syphilis and chlamydia cases each grew 11 percent over the one-year period, and gonorrhea cases ...
Louisiana ranked No. 2 in chlamydia, gonorrhea, syphilis rates ...NOLA.com
Georgia among worst states for chlamydia, gonorrhea and syphilis rates, CDC report saysAtlanta Journal Constitution
Louisiana Ranks 2nd for Chlamydia, Gonorrhea, Syphilis RatesU.S. News & World Report
Press of Atlantic City -Enumclaw Courier-Herald
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Japan is hoping Sailor Moon can fix its syphilis problem VICE News - VICE News


VICE News

Japan is hoping Sailor Moon can fix its syphilis problem VICE News
VICE News
The numbers are in. STDs in the United States are at an all-time high. The Centers for Disease Control says that more that 2 million cases of chlamydia, ...

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Babies being born with birth defects from congenital syphilis - NY ... - New York Daily News


New York Daily News

MSM in London diagnosed with early syphilis are a priority group for PrEP, suggests UK study - aidsmap


MSM in London diagnosed with early syphilis are a priority group for PrEP, suggests UK study
aidsmap
Gay and other men who have sex with men (MSM) recently diagnosed with early syphilis are a priority group for HIV pre-exposure prophylaxis (PrEP), results of a study published in Sexually Transmitted Infections suggest. Over two years of follow-up, 11 ...

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Treponema genome sequence annotation status: click numbers to browse lists of genes or subsystems

Strain annotated in NMPDR Genome size, bp Protein Encoding Genes (PEGs) Sort Named genes in subsystems Named genes not in subsystems Hypothetical genes in subsystems Hypothetical genes not in subsystems Subsystems RNAs
Treponema denticola ATCC 35405 2,843,201 2,769 717(25.4%) 983(34.8%) 9(0.3%) 1119(39.6%) 251 52
Treponema pallidum subsp. pallidum str. Nichols 1,138,011 1,057 454(41.4%) 564(51.4%) 1(0.1%) 78(7.1%) 183 82

Topic revision: r3 - 02 Mar 2009 - 00:03:21 - TWiki Guest
 
Notice to NMPDR Users - The NMPDR BRC contract has ended and bacterial data from NMPDR has been transferred to PATRIC (http://www.patricbrc.org), a new consolidated BRC for all NIAID category A-C priority pathogenic bacteria. NMPDR was a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.