Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae;

Treponema

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Treponema

I. Organism Information

A. Taxonomy Information

1. Species

a. Treponema pallidum

i. Taxonomy ID: 157

ii. Description:

Treponema pallidum is a motile spirochaete that is generally acquired by close sexual contact and can also be transmitted to a fetus during the later stages of pregnancy, giving rise to congenital syphilis. The helical structure of T. pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. It gains access to host's blood and lymph systems through tissue and mucus membranes. Treponema pallidum subsp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of inside a host.


iii. Variants

Treponema pallidum subsp. pallidum str. Nichols
Taxonomy ID: 243276


II. References

1.  Lafond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006 Jan;19(1):29-49.

2. Peeling RW, Hook EW 3rd. The pathogenesis of syphilis: the Great Mimicker, revisited. J Pathol. 2006 Jan;208(2):224-32.

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syphilis - Google News

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Review: Embodying the humanity in the drama of the Tuskegee syphilis study - Salt Lake Tribune


Utah Theater Bloggers Association

Review: Embodying the humanity in the drama of the Tuskegee syphilis study
Salt Lake Tribune
Separately spotlighted to her right, prizewinning young dancer Willie (Sean J. Carter) struggles to practice steps on a leg he is swiftly losing to syphilis. Isolated in their own light to her left are the two doctors one black (Brien Jones) and one ...
Strong script lifts MISS EVERS' BOYSUtah Theater Bloggers Association (blog)

all 2 news articles »

Planned Parenthood sues TN over cuts to STD program - The Tennessean


WBIR-TV

Planned Parenthood sues TN over cuts to STD program
The Tennessean
Larry McCormack / The Tennessean Abortion opponents are claiming another victory in the battle to defund Planned Parenthood by excluding it from state and federal funding for HIV and syphilis prevention programs. Two Tennessee Planned Parenthood groups ...
Planned Parenthood sues Tennessee health department over funding lossDeSoto Appeal
Planned Parenthood Files Suit Against Dept. Of HealthNewsChannel5.com
TN Lawsuit says Leaders Put Politics Ahead of HealthPublic News Service
Elizabethton Star -Nashville Public Radio -WREG
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Number of sex infections in over-45s doubles in 10 years due to rising divorce ... - Daily Mail


Daily Mail

Number of sex infections in over-45s doubles in 10 years due to rising divorce ...
Daily Mail
Cases of chlamydia and herpes have more than doubled in ten years, while syphilis which was almost eradicated ten years ago have risen fourfold. Researchers say one in five adults receiving HIV treatment is at least 50 twice as many in that age ...
Cases of sexually transmitted infections double in a decade among older BritsMirror.co.uk
HIV infection double among the elderlyTimes of India
STI rates double in older adults over last decadeCTV.ca
Scotsman -London Free Press
all 51 news articles »

Men who have sex with men and syphilis risk - Private MD


Private MD

Men who have sex with men and syphilis risk
Private MD
Rates of syphilis infection are rising at alarming speeds, and all sexually active young people should take steps to protect themselves from infection, which may include seeking STD testing for themselves and their partners. However, men who have sex ...

Number of Floridians infected with syphilis dramatically increases - Florida Courier


Private MD

Number of Floridians infected with syphilis dramatically increases
Florida Courier
BY RHETTA PEOPLES Statistics show people living in the area along the I-4 corridor in Florida may be infected with syphilis at a higher rate than previous years. According to the Center for Disease Control and Prevention (CDC), syphilis is a sexually ...
Sexually transmitted diseases mapped out with CDC digital health atlasMedCity News

all 3 news articles »

Syphilis Cases Increase In SW Ohio - Ohio News Network


Syphilis Cases Increase In SW Ohio
Ohio News Network
Dayton and Montgomery counties' public health officials said that high numbers of syphilis cases in Cincinnati are to blame for an increase in syphilis cases in Dayton. Montgomery County has seen the number of syphilis cases more than double in just a ...
Dayton worried about Cincinnati syphilisCincinnati.com (blog)
Sexually transmitted diseases spreading in SW OhioMarion Star

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Dr. Jeffrey Botkin to Participate in MISS EVERS' BOYS Talkback at the Grand ... - Broadway World


Dr. Jeffrey Botkin to Participate in MISS EVERS' BOYS Talkback at the Grand ...
Broadway World
The play, based on the Tuskegee syphilis experiment, was a finalist for the Pulitzer Prize for Drama that same year. As part of the production, the theatre is hosting a talk back after the 2:00 pm matinee performance on Saturday, February 11.
EttaGrace Company brings the Tuskegee Experiment to lifeExaminer.com

all 2 news articles »

Cincinnati Disputes Claim That City is Spreading Syphilis - WKRC TV Cincinnati


Private MD

Cincinnati Disputes Claim That City is Spreading Syphilis
WKRC TV Cincinnati
Cincinnati is dealing with an outbreak of syphilis and has been for several years. Now, officials in a city to our north say cases from Cincinnati are traveling up Interstate 75. Local 12 News reporter Angenette Levy went to the Cincinnati Department ...
Ohio: STD Surge in Cincinnati Hits Dayton RegionTheBody.com
Communities see STD rates risePrivate MD

all 3 news articles »

Search for syphilis cure in Kunal's new fiction - Times of India


Zee News

Search for syphilis cure in Kunal's new fiction
Times of India
The remedy for the 19th century scourge of syphilis, ancient Chinese therapies and a West-meets-East love story in which a young Portuguese doctor comes to China to learn its medicine and philosophy in the backdrop of the Boxer Rebellion is the ...
The Unfamiliar Excites Me, Says Novelist Kunal BasuOutlook

all 6 news articles »

Let's talk about sex! - QNotes


QNotes

Let's talk about sex!
QNotes
The program is identified as Stopping Mecklenburg's Acceleration of Syphilis and HIV, also known as SMASH. Currently, Mecklenburg County has the highest rate of syphilis in the state. Through SMASH people are able to access free and confidential HIV ...
Health Worker Presses For Screening Tests of STDsTopNews United States
STDs in baby boomers increasingUPI.com
Sex Life of Older Adults and Rising STDsABC News (blog)
The Ranger -Irish Times -AOL Lifestyle UK
all 83 news articles »

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Treponema genome sequence annotation status: click numbers to browse lists of genes or subsystems

Strain annotated in NMPDR Genome size, bp Protein Encoding Genes (PEGs) Sort Named genes in subsystems Named genes not in subsystems Hypothetical genes in subsystems Hypothetical genes not in subsystems Subsystems RNAs
Treponema denticola ATCC 35405 2,843,201 2,769 717(25.4%) 983(34.8%) 9(0.3%) 1119(39.6%) 251 52
Treponema pallidum subsp. pallidum str. Nichols 1,138,011 1,057 454(41.4%) 564(51.4%) 1(0.1%) 78(7.1%) 183 82

Topic revision: r3 - 02 Mar 2009 - 00:03:21 - Leslie Mc Neil
 
Notice to NMPDR Users - The NMPDR BRC contract has ended and bacterial data from NMPDR has been transferred to PATRIC (http://www.patricbrc.org), a new consolidated BRC for all NIAID category A-C priority pathogenic bacteria. NMPDR was a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.