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I. Organism Information
A. Taxonomy Information
1. Species
a. V. cholerae
i. Taxonomy ID: 666
ii. Description:
Vibrio cholerae is a Gram negative, motile, curved rod. Its main portal of entry is via oral ingestion of contaminated food or water. More than 138 serogroups are known. Serogroup O1 is responsible for pandemic cholera and is divided into two biotypes, Classical and El Tor. The El Tor biotype is responsible for the current cholera pandemic.
To contribute a blurb on serotypes, biotypes, or handling the organism in healthcare or laboratory facilities, please contact help@nmpdr.org Your contribution will be credited with a byline.
iii. Variants
Vibrio cholerae serotype O1
Vibrio cholerae serotype O139
Taxonomy ID: 45888
Vibrio cholerae serotype non-O1/non-O139
Taxonomy ID: 156539
b. V. parahaemolyticus
c. V. vulnificus
B. Lifecycle and Morphology
1. V. cholerae
a. Free-swimming
The vibrio life cycle consists of a free-swimming phase in marine and estuarine environments in association with zooplankton, crustaceans, insects, and water plants. Vibrios interact with various surfaces found in the environment to generate biofilms, which may promote survival.
i. Shape: Flagellated cell is 0.5-0.8 µm in width and 1.4-2.6 µm in length. Monotrichous or multitrichous flagella are enclosed in a sheath continuous with the outer membrane of the cell wall. On solid media, cells may produce numerous lateral flagella with a wavelength shorter than that of the sheathed polar flagellum.
b. Host phase
The host phase of the vibrio life cycle is only possible through the action of a group of virulence genes in the ToxR regulon controlled by a complex and incompletely understood regulatory cascade. The ToxR regulon colonization and toxin genes are coordinately expressed in response to specific host signals that have yet to be completely defined.
Hide infoVibrio - Google News
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We can make cholera history, and why not? IPPmedia, United Republic of Tanzania - A highly quotable health expert says: Cholera is an infection caused by Vibrio cholerae. Its incubation period ranges from a few hours to five days. ... |
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| Strain annotated in NMPDR | Genome size, bp | Protein Encoding Genes (PEGs) | Named genes in subsystems | Named genes not in subsystems | Hypothetical genes in subsystems | Hypothetical genes not in subsystems | Subsystems | RNAs |
|---|---|---|---|---|---|---|---|---|
| Vibrio alginolyticus 12G01 | 5,160,431 | 4,488 | 1608(36.0%) | 1776(39.8%) | 52(1.2%) | 1028(23.0%) | 267 | 120 |
| Vibrio cholerae 1587 | 4,137,501 | 3,243 | 1451(43.4%) | 1203(36.0%) | 44(1.3%) | 648(19.4%) | 297 | 134 |
| Vibrio cholerae 2740-80 | 3,945,478 | 3,150 | 1403(43.4%) | 1173(36.2%) | 45(1.4%) | 615(19.0%) | 292 | 117 |
| Vibrio cholerae AM-19226 | 4,056,157 | 3,202 | 1450(43.8%) | 1200(36.3%) | 49(1.5%) | 610(18.4%) | 297 | 136 |
| Vibrio cholerae MAK 757 | 3,917,446 | 3,154 | 1470(45.1%) | 1181(36.2%) | 46(1.4%) | 561(17.2%) | 298 | 139 |
| Vibrio cholerae MO10 | 4,024,286 | 3,439 | 1668(48.5%) | 1088(31.6%) | 70(2.0%) | 613(17.8%) | 330 | 29 |
| Vibrio cholerae MZO-3 | 4,146,039 | 3,162 | 1405(43.3%) | 1201(37.0%) | 47(1.4%) | 595(18.3%) | 297 | 116 |
| Vibrio cholerae NRT36s | 4,204,651 | 4,435 | 1812(42.8%) | 1475(34.8%) | 73(1.7%) | 873(20.6%) | 329 | 56 |
| Vibrio cholerae O1 biovar eltor str. N16961 | 4,033,464 | 3,908 | 1831(43.8%) | 1204(28.8%) | 73(1.7%) | 1069(25.6%) | 358 | 150 |
| Vibrio cholerae O395 | 4,132,319 | 3,317 | 1618(47.1%) | 1124(32.7%) | 61(1.8%) | 635(18.5%) | 333 | 152 |
| Vibrio fischeri ES114 | 4,284,050 | 3,805 | 1869(47.0%) | 1230(30.9%) | 52(1.3%) | 829(20.8%) | 341 | 175 |
| Vibrio harveyi ATCC BAA-1116 | 6,058,377 | 4,218 | 1619(38.4%) | 1769(41.9%) | 40(0.9%) | 790(18.7%) | 303 | 41 |
| Vibrio parahaemolyticus RIMD 2210633 | 5,165,770 | 4,866 | 2083(41.4%) | 1555(30.9%) | 81(1.6%) | 1311(26.1%) | 363 | 188 |
| Vibrio sp. Ex25 | 4,839,877 | 4,238 | 1819(42.9%) | 1410(33.3%) | 78(1.8%) | 931(22.0%) | 337 | 28 |
| Vibrio sp. MED222 | 4,891,901 | 4,301 | 1902(43.1%) | 1349(30.5%) | 61(1.4%) | 1105(25.0%) | 340 | 143 |
| Vibrio splendidus 12B01 | 5,596,386 | 4,933 | 1894(37.7%) | 1694(33.7%) | 64(1.3%) | 1376(27.4%) | 341 | 123 |
| Vibrio vulnificus CMCP6 | 5,126,798 | 4,514 | 1956(42.4%) | 1563(33.9%) | 74(1.6%) | 1024(22.2%) | 356 | 137 |
| Vibrio vulnificus YJ016 | 5,260,086 | 4,925 | 2026(39.8%) | 1491(29.3%) | 67(1.3%) | 1504(29.6%) | 364 | 164 |